Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kei Ichi Muraoka"'
Autor:
Akiko Ikeda, Katsuji Yoshioka, Xiangao Sun, Kei Ichi Muraoka, Shigeki Miyamoto, Yong Kang Zhang, Hiroko Shimizu, Ken Ichi Yamamoto
Publikováno v:
Journal of Biological Chemistry. 274:34657-34662
The immunosuppressant FK506 activates NF-κB through IκBα degradation in nonlymphoid cells. In the present study, we analyzed mechanisms by which FK506 induces IκBα degradation. We found that FK506 induces the degradation of both IκBα and IκB
Autor:
Tetsuo Hashimoto, Yong Kang Zhang, Ken Ichi Yamamoto, Kouichi Shimizu, Takashi Tani, Masao Yagi, Xiangao Sun, Itsuo Miyazaki, Kei Ichi Muraoka
Publikováno v:
Transplantation. 63:466-470
Interleukin (IL) 6 is one of major mediators of inflammation, and IL-6 gene activation during hypoxia/reoxygenation has been implicated in the pathogenesis of ischemia/reperfusion injury. However, molecular events involved in IL-6 gene expression dur
Autor:
Xiangao Sun, Kei Ichi Muraoka, Ken Ichi Yamamoto, Koutaro Fujimoto, Masao Yagi, Kou Ichi Shimizu, Henry R Bose, Itsuo Miyazaki, Katsuji Yoshioka
Publikováno v:
Journal of Clinical Investigation. 97(11):2433-2439
金沢大学がん研究所がん分子細胞制御
FK506 is a powerful immunosuppressive drug currently in use that inhibits the activation of several transcription factors (nuclear factor (NF)-AT and NF-κB) critical for T cell activation. We
FK506 is a powerful immunosuppressive drug currently in use that inhibits the activation of several transcription factors (nuclear factor (NF)-AT and NF-κB) critical for T cell activation. We