Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kei Asaji"'
Autor:
Koichi Kikuchi, Daisuke Saigusa, Yoshitomi Kanemitsu, Yotaro Matsumoto, Paxton Thanai, Naoto Suzuki, Koki Mise, Hiroaki Yamaguchi, Tomohiro Nakamura, Kei Asaji, Chikahisa Mukawa, Hiroki Tsukamoto, Toshihiro Sato, Yoshitsugu Oikawa, Tomoyuki Iwasaki, Yuji Oe, Tomoya Tsukimi, Noriko N. Fukuda, Hsin-Jung HO, Fumika Nanto-Hara, Jiro Ogura, Ritsumi Saito, Shizuko Nagao, Yusuke Ohsaki, Satoshi Shimada, Takehiro Suzuki, Takafumi Toyohara, Eikan Mishima, Hisato Shima, Yasutoshi Akiyama, Yukako Akiyama, Mariko Ichijo, Tetsuro Matsuhashi, Akihiro Matsuo, Yoshiaki Ogata, Ching-Chin Yang, Chitose Suzuki, Matthew C. Breeggemann, Jurgen Heymann, Miho Shimizu, Susumu Ogawa, Nobuyuki Takahashi, Takashi Suzuki, Yuji Owada, Shigeo Kure, Nariyasu Mano, Tomoyoshi Soga, Takashi Wada, Jeffrey B. Kopp, Shinji Fukuda, Atsushi Hozawa, Masayuki Yamamoto, Sadayoshi Ito, Jun Wada, Yoshihisa Tomioka, Takaaki Abe
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Diabetes is a major cause of kidney disease. Here Kikuchi et al. show that phenol sulfate, a gut microbiota-derived metabolite, is increased in diabetic kidney disease and contributes to the pathology by promoting kidney injury, suggesting phenyl sul
Externí odkaz:
https://doaj.org/article/4b7ee8aaa8cd44e3ba881e3d9e920e28
Autor:
Tomoyoshi Soga, Sadayoshi Ito, Eikan Mishima, Chitose Suzuki, Noriko N. Fukuda, Yotaro Matsumoto, Daisuke Saigusa, Takehiro Suzuki, Tatsuki Tachikawa, Chikahisa Mukawa, Yoshitomi Kanemitsu, Hiroki Tsukamoto, Yoshihisa Tomioka, Koichi Kikuchi, Kei Asaji, Fumika Nanto, Hsin Jung Ho, Shinji Fukuda, Takaaki Abe, Tomoya Tsukimi
Publikováno v:
American Journal of Physiology-Renal Physiology. 315:F824-F833
Accumulation of uremic toxins, which exert deleterious effects in chronic kidney disease, is influenced by the intestinal environment; the microbiota contributes to the production of representative uremic toxins, including p-cresyl sulfate and indoxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::586ce5cdb17de8cd4555fe6301ff790e
https://doi.org/10.1152/ajprenal.00314.2017
https://doi.org/10.1152/ajprenal.00314.2017
Autor:
Kei Asaji, Yoshihisa Tomioka, Takehiro Suzuki, Noriko N. Fukuda, Yasutoshi Akiyama, Yoshitomi Kanemitsu, Takaaki Abe, Hiroki Tsukamoto, Yotaro Matsumoto, Koichi Kikuchi, Shinji Fukuda, Tomoyoshi Soga, Eikan Mishima, Akinori Yuri, Chitose Suzuki, Sadayoshi Ito, Chikahisa Mukawa, Hisato Shima
Publikováno v:
Kidney International. 92:634-645
Gut microbiota is involved in the metabolism of uremic solutes. However, the precise influence of microbiota to the retention of uremic solutes in CKD is obscure. To clarify this, we compared adenine-induced renal failure and control mice under germ-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b1890fdf52026c83d3359b7dd87b6a2
https://doi.org/10.1016/j.kint.2017.02.011
https://doi.org/10.1016/j.kint.2017.02.011
Autor:
Takehiro Suzuki, Yotaro Matsumoto, Chikahisa Mukawa, Tomoya Tsukimi, Jun Wada, Hiroki Tsukamoto, Yuji Oe, Takaaki Abe, Naoto Suzuki, Nobuyuki Takahashi, Tetsuro Matsuhashi, Yuji Owada, Jurgen Heymann, Hiroaki Yamaguchi, Yukako Akiyama, Chitose Suzuki, Paxton Thanai, Ritsumi Saito, Satoshi Shimada, Ching Chin Yang, Tomohiro Nakamura, Fumika Nanto-Hara, Susumu Ogawa, Daisuke Saigusa, Matthew C. Breeggemann, Koichi Kikuchi, Masayuki Yamamoto, Akihiro Matsuo, Yoshitomi Kanemitsu, Jeffrey B. Kopp, Shinji Fukuda, Sadayoshi Ito, Tomoyuki Iwasaki, Yasutoshi Akiyama, Mariko Ichijo, Atsushi Hozawa, Miho Shimizu, Toshihiro Sato, Takafumi Toyohara, Yoshihisa Tomioka, Tomoyoshi Soga, Yoshiaki Ogata, Nariyasu Mano, Koki Mise, Jiro Ogura, Eikan Mishima, Noriko N. Fukuda, Takashi Suzuki, Shizuko Nagao, Kei Asaji, Takashi Wada, Yusuke Ohsaki, Hisato Shima, Hsin Jung Ho, Yoshitsugu Oikawa, Shigeo Kure
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Diabetic kidney disease is a major cause of renal failure that urgently necessitates a breakthrough in disease management. Here we show using untargeted metabolomics that levels of phenyl sulfate, a gut microbiota-derived metabolite, increase with th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53539ee350baef3ab3064425f4e6578
http://europepmc.org/articles/PMC6478834
http://europepmc.org/articles/PMC6478834
Autor:
Tomoyoshi Soga, Eikan Mishima, Sadayoshi Ito, Kei Asaji, Daisuke Saigusa, Yukako Akiyama, Hsin Jung Ho, Fumika Nanto-Hara, Tomoyuki Iwasaki, Yoshitomi Kanemitsu, Koichi Kikuchi, Takehiro Suzuki, Shinji Fukuda, Tetsuro Matsuhashi, Yuji Owada, Tomoya Tsukimi, Yoshitsugu Oikawa, Takaaki Abe, Chitose Suzuki, Yoshihisa Tomioka, Shigeo Kure
Publikováno v:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 35(2)
Background Cardiorenal syndrome is a major cause of mortality in patients with chronic kidney disease (CKD). However, the involvement of detrimental humoral mediators in the pathogenesis of cardiorenal syndrome is still controversial. Trimethylamine-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8721225c609a6ca5ab9f4f13426bb4c5
https://pubmed.ncbi.nlm.nih.gov/31411705
https://pubmed.ncbi.nlm.nih.gov/31411705
Autor:
Tatsuki Tachikawa, Yoshitomi Kanemitsu, Daisuke Saigusa, Chikahisa Mukawa, Kei Asaji, Takaaki Abe, Yotaro Matsumoto, Yoshihisa Tomioka, Hiroki Tsukamoto
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
Column choice is crucial to the development of liquid chromatography/tandem mass spectrometry (LC-MS/MS) methods because analyte selectivity is dependent on the nature of the stationary phase. Recently, mixed-mode chromatography, which employs a comb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aea340d0307f7cf2cb83bfe76afc57e
https://pubmed.ncbi.nlm.nih.gov/29024911
https://pubmed.ncbi.nlm.nih.gov/29024911
Autor:
Eikan Mishima, Shinji Fukuda, Yoshitomi Kanemitsu, Daisuke Saigusa, Chikahisa Mukawa, Kei Asaji, Yotaro Matsumoto, Hiroki Tsukamoto, Tatsuki Tachikawa, Tomoya Tsukimi, Fukuda, Noriko N., Hsin-Jung Ho, Koichi Kikuchi, Chitose Suzuki, Fumika Nanto, Takehiro Suzuki, Sadayoshi Ito, Tomoyoshi Soga, Yoshihisa Tomioka, Takaaki Abe
Publikováno v:
American Journal of Physiology: Renal Physiology; Oct2018, Vol. 315 Issue 4, pF824-F833, 10p