Zobrazeno 1 - 10
of 674
pro vyhledávání: '"Kei, Ohkubo"'
Autor:
Ryota Mori, Masami Abe, Yuma Saimoto, Saki Shinto, Sara Jodai, Manami Tomomatsu, Kaho Tazoe, Minato Ishida, Masataka Enoki, Nao Kato, Tomohiro Yamashita, Yuki Itabashi, Ikuo Nakanishi, Kei Ohkubo, Sachiko Kaidzu, Masaki Tanito, Yuta Matsuoka, Kazushi Morimoto, Ken-ichi Yamada
Publikováno v:
Redox Biology, Vol 73, Iss , Pp 103186- (2024)
Recent studies have highlighted the indispensable role of oxidized lipids in inflammatory responses, cell death, and disease pathogenesis. Consequently, inhibitors targeting oxidized lipids, particularly lipid-derived radicals critical in lipid perox
Externí odkaz:
https://doaj.org/article/7d182cc53e094558b215ae9e0f93a292
Publikováno v:
Antioxidants, Vol 13, Iss 10, p 1165 (2024)
Planar catechin (PCat), a natural antioxidant with a fixed 3D catechin structure on a plane, exhibits radical-scavenging activity approximately five times stronger than the conventional catechin. We synthesized a compound, PCat-TrOH, by binding Trolo
Externí odkaz:
https://doaj.org/article/a4acb9e80e524b6483f72df6bd3ea9f2
Autor:
Daisuke Masuda, Ikuo Nakanishi, Kei Ohkubo, Hiromu Ito, Ken-ichiro Matsumoto, Hiroshi Ichikawa, Moragot Chatatikun, Wiyada Kwanhian Klangbud, Manas Kotepui, Motoki Imai, Fumitaka Kawakami, Makoto Kubo, Hirofumi Matsui, Jitbanjong Tangpong, Takafumi Ichikawa, Toshihiko Ozawa, Hsiu-Chuan Yen, Daret K. St Clair, Hiroko P. Indo, Hideyuki J. Majima
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 128 (2024)
Questions about which reactive oxygen species (ROS) or reactive nitrogen species (RNS) can escape from the mitochondria and activate signals must be addressed. In this study, two parameters, the calculated dipole moment (debye, D) and permeability co
Externí odkaz:
https://doaj.org/article/2f9fcb72f1c247bc85463ff752e569d2
Publikováno v:
Journal of Photochemistry and Photobiology, Vol 15, Iss , Pp 100184- (2023)
2-Aza-9-fluorenone derivatives were synthesized and their optical properties were investigated. The UV–visible absrption spectra revealed λmax values in the range of 350–380 nm, with a shift to the longer wavelength when an electron-donating gro
Externí odkaz:
https://doaj.org/article/21424728810c47a2861197925ffaf21d
Publikováno v:
Molecules, Vol 28, Iss 13, p 5002 (2023)
A neutral, stable radical, 2,2-diphenyl-1-picrylhydrazyl radical (DPPH•), has been frequently used to estimate the activity of antioxidants for more than 60 years. However, the number of reports about the effect of metal ions on the reactivity of D
Externí odkaz:
https://doaj.org/article/bbaa4f59a72e448f8de1f089d0b53a0f
Autor:
Ikuo Nakanishi, Yoshimi Shoji, Kei Ohkubo, Megumi Ueno, Kei Shimoda, Ken-ichiro Matsumoto, Kiyoshi Fukuhara, Hiroki Hamada
Publikováno v:
Antioxidants, Vol 11, Iss 2, p 340 (2022)
Pterostilbene (PTS), a methylated analog of resveratrol (RSV), has recently attracted much attention due to its enhanced bioavailability compared to RSV. However, little is known about the radical-scavenging mechanism of PTS. In this study, we invest
Externí odkaz:
https://doaj.org/article/5739f46030c74169b3ae230cad6448a6
Autor:
Hajime Shigemitsu, Kazuhide Sato, Satomi Hagio, Youhei Tani, Tadashi Mori, Kei Ohkubo, Yasuko Osakada, Mamoru Fujitsuka, Toshiyuki Kida
Publikováno v:
ACS Applied Nano Materials. 5:14954-14960
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3675670f73498da23cd9f418ca69953
https://doi.org/10.1021/acsanm.2c03192
https://doi.org/10.1021/acsanm.2c03192
Publikováno v:
Antioxidants, Vol 10, Iss 12, p 1966 (2021)
Recently, increasing attention has been paid to quantum mechanical behavior in biology. In this study, we investigated the involvement of quantum mechanical tunneling in the hydrogen-transfer reaction from Trolox, a water-soluble analog of vitamin E
Externí odkaz:
https://doaj.org/article/c9940033bea14c039a9c0f138bd2780a
Autor:
Yudai Kaneko, Kenzo Yamatsugu, Takefumi Yamashita, Kazuki Takahashi, Toshiya Tanaka, Sho Aki, Toshifumi Tatsumi, Takeshi Kawamura, Mai Miura, Masazumi Ishii, Kei Ohkubo, Tsuyoshi Osawa, Tatsuhiko Kodama, Shumpei Ishikawa, Masanobu Tsukagoshi, Michael Chansler, Akira Sugiyama, Motomu Kanai, Hiroto Katoh
Publikováno v:
Cancer Science. 113:4350-4362
Antibody-mimetic drug conjugate is a novel noncovalent conjugate consisting of an antibody-mimetic recognizing a target molecule on the cancer cell surface and low-molecular-weight payloads that kill the cancer cells. In this study, the efficacy of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c514ca8d795582a53ba11a4ebf1b1e
https://doi.org/10.1111/cas.15565
https://doi.org/10.1111/cas.15565
Autor:
Yuka Tajimi, Yasuhiro Nachi, Ryoko Inada, Ryoga Hashimoto, Mugen Yamawaki, Kei Ohkubo, Toshio Morita, Yasuharu Yoshimi
Publikováno v:
The Journal of Organic Chemistry. 87:7405-7413
Visible-light-induced decarboxylative and deboronative reactions using two-molecule organic photoredox catalysts, namely, phenanthrene (Phen) and biphenyl (BP), as electron donors and 9-cyano-10-methoxycarbonylanthracene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::572b9bfb912c294053704f3e1d54f3ed
https://doi.org/10.1021/acs.joc.2c00643
https://doi.org/10.1021/acs.joc.2c00643