Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kei, Motonaga"'
Autor:
Linda Gijzen, Kouichi Yoshinari, Niels Ouwerkerk, Kei Motonaga, Marleen Bokkers, Yuki Hagiwara, Remko van Vught, Harumi Kumagai, Tomokazu Tajiri, Rumaisha Annida, Yoshifumi Katakawa
Publikováno v:
Journal of Pharmaceutical Sciences. 111:214-224
The aim of this study was to develop an in vitro drug permeability methodology which mimics the gastrointestinal environment more accurately than conventional 2D methodologies through a three-dimensional (3D) Caco-2 tubules using a microphysiological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536eaebc2e2e2421c39c2c797264f2bf
https://doi.org/10.1016/j.xphs.2021.11.016
https://doi.org/10.1016/j.xphs.2021.11.016
Autor:
Shin-ichiro Kimura, Masanori Kaihara, Yasunori Iwao, Yoshifumi Katakawa, Kei Motonaga, Kazuhiro Hojo, Hiromu Kondo, Takatsune Yoshida, Tomokazu Tajiri, Atsushi Kambayashi
Publikováno v:
Chemical and Pharmaceutical Bulletin. 67:467-475
The aim of this study was to establish a novel approach to in vitro dissolution evaluation using a combination of the paddle method and a dialysis membrane, both to predict the overall in vivo performance of tacrolimus microspheres and also to identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::716df3c02f70a77a984fb69fe39b75e1
https://doi.org/10.1248/cpb.c18-01018
https://doi.org/10.1248/cpb.c18-01018
Autor:
Masanori, Kaihara, Kazuhiro, Hojo, Tomokazu, Tajiri, Atsushi, Kambayashi, Takatsune, Yoshida, Yoshifumi, Katakawa, Kei, Motonaga, Shin-Ichiro, Kimura, Yasunori, Iwao, Hiromu, Kondo
Publikováno v:
Chemicalpharmaceutical bulletin. 67(5)
The aim of this study was to establish a novel approach to in vitro dissolution evaluation using a combination of the paddle method and a dialysis membrane, both to predict the overall in vivo performance of tacrolimus microspheres and also to identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3ab524a32c8728397b03077d673cc0d0
https://pubmed.ncbi.nlm.nih.gov/31061372
https://pubmed.ncbi.nlm.nih.gov/31061372
Autor:
Maria Vertzoni, Kei Motonaga, Niels Ouwerkerk, Christos Reppas, Yoshifumi Katakawa, Daisuke Murayama, Yosuke Yamamoto, Moe Haneda, Tomokazu Tajiri, Harumi Kumagai
Publikováno v:
European Journal of Pharmaceutical Sciences. 142:105107
The main objective of this study was to investigate the mechanism of solifenacin release from a pH-responsive ion-complex oral resinate suspension under conditions simulating the environment in the upper gastrointestinal lumen. A secondary objective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e96b1c0f5519696a6c0d79607e43ed5
https://doi.org/10.1016/j.ejps.2019.105107
https://doi.org/10.1016/j.ejps.2019.105107
Publikováno v:
Environmental Toxicology and Chemistry. 17:1469-1472
Mechanisms of degradation suppression of chlorothalonil after repeated application were investigated. Under laboratory conditions, soil was treated sequentially with 40 mg/kg dry weight of chlorothalonil. This resulted in the degradation suppression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e723a889795dca8ad3201075430266f
https://doi.org/10.1002/etc.5620170806
https://doi.org/10.1002/etc.5620170806