Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Kehui Xiang"'
Autor:
Kehui Xiang, David P Bartel
Publikováno v:
eLife, Vol 10 (2021)
In animal oocytes and early embryos, mRNA poly(A)-tail length strongly influences translational efficiency (TE), but later in development this coupling between tail length and TE disappears. Here, we elucidate how this coupling is first established a
Externí odkaz:
https://doaj.org/article/7737bd3ba53542a6a98b01b3461f498a
Autor:
Hao Huang, Miranda Trentle, Zexin Liu, Kehui Xiang, William Higgins, Yunbing Wang, Bing Xue, Shuguang Yang
Publikováno v:
ACS Applied Materials & Interfaces. 15:7639-7662
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71f1f883278366d87df551c1c838686f
https://doi.org/10.1021/acsami.2c19583
https://doi.org/10.1021/acsami.2c19583
Autor:
David P. Bartel, Kehui Xiang
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
In animal oocytes and early embryos, mRNA poly(A)-tail length strongly influences translational efficiency (TE), but later in development this coupling between tail length and TE disappears. Here, we elucidate how this coupling is first established a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d71367a546a5af0a1798ab178b350beb
http://europepmc.org/articles/PMC8253595
http://europepmc.org/articles/PMC8253595
Publikováno v:
Molecular and Cellular Biology. 34:2488-2498
The C-terminal domain of the RNA polymerase II largest subunit (the Rpb1 CTD) is composed of tandem heptad repeats of the consensus sequence Y(1)S(2)P(3)T(4)S(5)P(6)S(7). We reported previously that Thr 4 is phosphorylated and functions in histone mR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c38e40a34cc53ccb188f3ea0cbe02cb0
https://doi.org/10.1128/mcb.00181-14
https://doi.org/10.1128/mcb.00181-14
Autor:
Kehui Xiang1, Nagaike, Takashi1, Song Xiang1,2, Kilic, Turgay1, Beh, Maia M.1, Manley, James L.1, Liang Tong1 ltong@columbia.edu
Publikováno v:
Nature. 10/7/2010, Vol. 467 Issue 7316, p729-733. 5p. 1 Color Photograph, 2 Diagrams, 1 Graph.
Publikováno v:
Nature structural & molecular biology
The 5′→ 3′ exoribonucleases (XRNs) have important functions in transcription, RNA metabolism, and RNA interference. The recent structure of Rat1 (Xrn2) showed that the two highly conserved regions of XRNs form a single, large domain, defining t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7552d633d5a785eec0ccafe672242c8b
http://europepmc.org/articles/PMC3075561
http://europepmc.org/articles/PMC3075561
Autor:
Maia M. Beh, Takashi Nagaike, Liang Tong, Song Xiang, Turgay Kilic, Kehui Xiang, James L. Manley
Publikováno v:
Nature
Symplekin (Pta1 in yeast) is a scaffold in the large protein complex that is required for 3′-end cleavage and polyadenylation of eukaryotic messenger RNA precursors (pre-mRNAs) 1–4, and also participates in transcription initiation and terminatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd7cacdcd6dbc791e2960987e5f4c80e
https://doi.org/10.1038/nature09391
https://doi.org/10.1038/nature09391
Processing of mRNA precursors (pre-mRNAs) by polyadenylation is an essential step in gene expression. Polyadenylation consists of two steps, cleavage and poly(A) synthesis, and requires multiple cis elements in the pre-mRNA and a megadalton protein c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04577d32d8c2c1ad459b20c6b14c4477
https://europepmc.org/articles/PMC4019069/
https://europepmc.org/articles/PMC4019069/
Autor:
David P. Bartel, Kehui Xiang
Publikováno v:
Cancer Immunology Research. 4:B132-B132
Translational control is an essential regulatory mechanism in immune cells. Although it has been suggested that poly(A) tail length-mediated translational control plays important roles in regulating select cytokine production in memory T cells and ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a0f0741ed2d8dd7505ffbfe2183d16f
https://doi.org/10.1158/2326-6066.imm2016-b132
https://doi.org/10.1158/2326-6066.imm2016-b132