Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kehao Wu"'
Publikováno v:
Visual Informatics, Vol 7, Iss 4, Pp 41-56 (2023)
How to explore fine-grained but meaningful information from the massive amount of social media data is critical but challenging. To address this challenge, we propose the TopicBubbler, a visual analytics system that supports the cross-level fine-grai
Externí odkaz:
https://doaj.org/article/69d8798fe32445a68a55f97b2e02e988
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Abstract It has been reported that geographical variation influences bone mineral density (BMD), obesity, and sarcopenia related traits in other countries. However, there is lack of similar studies in the US population. In this study, we compared dat
Externí odkaz:
https://doaj.org/article/43f8f79e0fea411a87e98d28ced3210d
Autor:
Lin-Ping Peng, Jun-Min Lu, Chun-Ping Zeng, Jie Shen, Xu Lin, Zeng-Xin Ao, Ding-You Li, Yan-Fang Guo, Jonathan Greenbaum, Hong-Wen Deng, Xia-Fang Wang, Rou Zhou, Yuan-Cheng Chen, Kehao Wu
Publikováno v:
Journal of the Neurological Sciences. 380:262-272
BACKGROUND: Both type 2 diabetes (T2D) and Alzheimer’s disease (AD) occur commonly in the aging populations and T2D has been considered as an important risk factor for AD. The heritability of both diseases is estimated to be over 50%. However, comm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a125867069877df1dcafb50f5eb110fa
https://doi.org/10.1016/j.jns.2017.07.044
https://doi.org/10.1016/j.jns.2017.07.044
Publikováno v:
JCSM clinical reports
Background Sarcopenia and sarcopenic obesity are emerging public health issues. True prevalence rates are unknown and estimates differ substantially between studies. No large-scale single study has compared prevalence rates between whites, blacks, As
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12b98aff713a8c31e9082de52e1e60af
https://pubmed.ncbi.nlm.nih.gov/31463425
https://pubmed.ncbi.nlm.nih.gov/31463425
Autor:
Hong-Wen Deng, Yong Zeng, Zhao Yc, Ji-Gang Zhang, Huang Hl, Lan-Juan Zhao, Lei Zhang, Hui Shen, Wei Zhu, Qing Tian, Kehao Wu, Hao He, Fei-Yan Deng, Yu Zhou
Publikováno v:
Osteoporosis International. 28:1035-1046
In male Caucasians with discordant hip bone mineral density (BMD), we applied the subcellular separation and proteome profiling to investigate the monocytic cytosol. Three BMD-associated proteins (ALDOA, MYH14, and Rap1B) were identified based on mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32a697bdb53d26856443f2be4abb0072
https://doi.org/10.1007/s00198-016-3825-y
https://doi.org/10.1007/s00198-016-3825-y
Publikováno v:
Genetic Epidemiology. 41:187-197
Next-generation sequencing-based genetic association study (GAS) is a powerful tool to identify candidate disease variants and genomic regions. Although low-coverage sequencing offers low cost but inadequacy in calling rare variants, high coverage is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c2635bb06b1ec3c9d14863237114b9c
https://doi.org/10.1002/gepi.22015
https://doi.org/10.1002/gepi.22015
Autor:
Hong-Wen Deng, Chao Xu, Yong Zeng, Ji-Gang Zhang, Lei Zhang, Yu Zhou, K.-J. Su, Kehao Wu, Hao He, Wei Zhu
Publikováno v:
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 29(12)
By integrating the multilevel biological evidence and bioinformatics analyses, the present study represents a systemic endeavor to identify BMD-associated genes and their roles in skeletal metabolism. Single-nucleotide polymorphism (SNP)-based genome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d62beb0e0cffae2e8304084653d30c
https://pubmed.ncbi.nlm.nih.gov/30306226
https://pubmed.ncbi.nlm.nih.gov/30306226
Autor:
Kehao Wu, Zeng-Xin Ao, Hong-Wen Deng, Zhang-Fang Li, Xu Lin, Tong Zhang, Cheng Peng, Jonathan Greenbaum, Jie Shen
OBJECTIVE: Dyslipidemia (DL) is closely related to osteoporosis (OP) while the exact common genetic mechanisms are still largely unknown. We proposed to use novel genetic analysis methods with pleiotropic information to identify potentially novel and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6602141c530f59c763fd10a40770eff3
https://europepmc.org/articles/PMC5949092/
https://europepmc.org/articles/PMC5949092/
Autor:
Jonathan Greenbaum, Xu Lin, Xuezhong Shi, Kehao Wu, Qiang Zhang, Yuan-Lin Xi, Yong Zeng, Wan-Qiang Lv, Jing-Yang He, Hong-Wen Deng, Weidong Zhang, Xin Xia, Hui-Min Liu, Changqing Sun
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Genome-wide association studies (GWASs) have been performed extensively in diverse populations to identify single nucleotide polymorphisms (SNPs) associated with complex diseases or traits. However, to date, the SNPs identified fail to explain a larg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90657b7b40d5248ad581a0c9951d16dd
https://pubmed.ncbi.nlm.nih.gov/29180724
https://pubmed.ncbi.nlm.nih.gov/29180724
Publikováno v:
Bone. 99
Although GWAS have been successful in identifying some osteoporosis associated loci, the findings explain only a small fraction of the total genetic variance. In this study we use a recently developed novel pleiotropic conditional false discovery rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f3dd7cface41f6bfaf2de00f77f499
https://pubmed.ncbi.nlm.nih.gov/28373146
https://pubmed.ncbi.nlm.nih.gov/28373146