Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kege Yang"'
Autor:
Hanming Yao, Chengzhi Huang, Jinmao Zou, Weiling Liang, Yue Zhao, Kege Yang, Ziyi Zhong, Shurui Zhou, Jiajia Li, Yaqing Li, Lishu Xu, Kaihong Huang, Guoda Lian
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 7, Pp n/a-n/a (2024)
Abstract Pancreatic ductal adenocarcinoma (PDAC) is characterised by immune evasion that contribute to poor prognosis. Cancer‐associated fibroblasts (CAFs) play a pivotal role in orchestrating the PDAC tumour microenvironment. We investigated the r
Externí odkaz:
https://doaj.org/article/e1bf69a7b1594b22a954c40d4f801f09
Autor:
Shurui Zhou, Kege Yang, Shaojie Chen, Guoda Lian, Yuzhou Huang, Hanming Yao, Yue Zhao, Kaihong Huang, Dong Yin, Haoming Lin, Yaqing Li
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background Intrahepatic cholangiocarcinoma (ICC) is a malignant disease characterized by onset occult, rapid progression, high relapse rate, and high mortality. However, data on how the tumor microenvironment (TME) regulates ICC metastasis a
Externí odkaz:
https://doaj.org/article/960007e200cd47a8bceafd6a29f41ada
Autor:
Yue Zhao, Hanming Yao, Kege Yang, Shiji Han, Shangxiang Chen, Yaqing Li, Shaojie Chen, Kaihong Huang, Guoda Lian, Jiajia Li
Publikováno v:
Biomaterials Science. 10:5989-6002
ScAb-ATO-NPs targets PSCs to increase the delivery efficiency of ATO to PSCs. ATO inhibits the activation of PSCs via PI3K/AKT/AP4/galectin-1 pathway and decreases the synthesis of ECM in PDAC, which enhances the chemotherapy in PDAC.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f98879d96986d95b8e8b289447d0d86e
https://doi.org/10.1039/d2bm01039a
https://doi.org/10.1039/d2bm01039a
Autor:
Shurui Zhou, Ziyi Zhong, Yanzong Lu, Yunlong Li, Hanming Yao, Yue Zhao, Tairan Guo, Kege Yang, Yaqing Li, Shaojie Chen, Kaihong Huang, Guoda Lian
Publikováno v:
Cancers; Volume 14; Issue 19; Pages: 4722
Pancreatic ductal adenocarcinoma (PDAC) is one of the highest mortalities malignant tumors, which is characterized by difficult diagnosis, rapid progression and high recurrence rate. Nevertheless, PDAC responds poorly to conventional therapies, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::426fa2d90ea12f671f9b2e9cc87ced0d
https://pubmed.ncbi.nlm.nih.gov/36230646
https://pubmed.ncbi.nlm.nih.gov/36230646
Autor:
Guoda Lian, Linjuan Zeng, Chumei Huang, Yinting Chen, Jiajia Li, Kege Yang, Shaojie Chen, Yaqing Li, Kaihong Huang, Qiubo Zhang
Publikováno v:
Cancer Medicine
Tumor‐associated macrophages (TAMs) are abundant population of inflammatory cells which play an essential role in remodeling tumor microenvironment and tumor progression. Previously, we found the high density of TAMs was correlated with lymph node
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c3f2517ffcb0ceb6600a4646574a02e
https://doi.org/10.1002/cam4.1824
https://doi.org/10.1002/cam4.1824
Autor:
Kege Yang, Jiajia Li, Linjuan Zeng, Yaqing Li, Chumei Huang, Kaihong Huang, Hong Su, Zuoquan Zhang, Yubo Guo, Jian Li, Yonghui Su, Guoda Lian, Shaojie Chen, Yinting Chen
Publikováno v:
Theranostics
The molecular mechanism of perineural invasion (PNI) is unclear, and insufficient detection during early-stage PNI in vivo hampers its investigation. We aimed to identify a cytokine paracrine loop between pancreatic ductal adenocarcinoma (PDAC) cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afbad92ac368d6fa398e55e2adbef2df
http://europepmc.org/articles/PMC5996366
http://europepmc.org/articles/PMC5996366
Autor:
Yaqing Li, Lingyun Wang, Linjuan Zeng, Chumei Huang, Zuoquan Zhang, Guoda Lian, Yinting Chen, Jiajia Li, Kaihong Huang, Ying Lin, Kege Yang, Shaojie Chen
Publikováno v:
Cancer Science
Tumor metastasis occurs naturally in pancreatic cancer, and the efficacy of chemotherapy is usually poor. Precision medicine, combining downregulation of target genes with chemotherapy drugs, is expected to improve therapeutic effects. Therefore, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc650a7746cfa494950638b33de0fee0
https://doi.org/10.1111/cas.13267
https://doi.org/10.1111/cas.13267
Autor:
Kege Yang, Linjuan Zeng, Yaqing Li, Kaihong Huang, Chen Yinting, Guoda Lian, Jiajia Li, Shaojie Chen
Publikováno v:
Journal of Biomedical Nanotechnology. 12:1654-1666
BACKGROUND: The concept of precision medicine to treat cancer shows promise and a co-delivery carrier for chemotherapy drugs and target genes is the key tool for both basic research and clinical application. To address this, we developed a cancer-tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7a1b2dd69746564efe6d6bbb668bd8b
https://doi.org/10.1166/jbn.2016.2269
https://doi.org/10.1166/jbn.2016.2269
Autor:
Kaihong Huang, Jiajia Li, Chumei Huang, Guoda Lian, Yaqing Li, Linjuan Zeng, Zhong-hua Chu, Shaojie Chen, Yinting Chen, Qiubo Zhang, Kege Yang
Publikováno v:
Tumor Biology. 37:11299-11309
It is critical to understand the pathogenesis of preinvasive stages of pancreatic duct adenocarcinoma (PDAC) for developing novel potential diagnostic and therapeutic targets. The polycomb group family member B-lymphoma Moloney murine leukemia virus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d624b7be56488963ce10239d211b13c
https://doi.org/10.1007/s13277-016-4840-5
https://doi.org/10.1007/s13277-016-4840-5
Autor:
Kege Yang, Kaihong Huang, Shaojie Chen, Hai-gang Li, Linjuan Zeng, Jiajia Li, Yinting Chen, Guangsheng Ou, Jian-ning Chen, Guoda Lian
Publikováno v:
Gastric Cancer. 19:392-402
B-cell-specific Moloney murine leukemia virus integration site 1 (Bmi-1) and Raf kinase inhibitory protein (RKIP) are involved in cancer metastasis and chemotherapeutic resistance, respectively. In this study, we evaluated the association between Bmi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1f912bd172fe5e6927ceefda221e7d5
https://doi.org/10.1007/s10120-015-0485-0
https://doi.org/10.1007/s10120-015-0485-0