Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Kefeng Lu"'
Autor:
Xulong Ding, Shuqiang Cao, Qing Wang, Bin Du, Kefeng Lu, Shiqian Qi, Ying Cheng, Qing‐zhang Tuo, Weibo Liang, Peng Lei
Publikováno v:
Advanced Science, Vol 11, Iss 15, Pp n/a-n/a (2024)
Abstract Traumatic brain injury (TBI) leads to progressive neurodegeneration that may be caused by chronic traumatic encephalopathy (CTE). However, the precise mechanism remains unclear. Herein, the study identifies a crucial protein, axonemal dynein
Externí odkaz:
https://doaj.org/article/dad6cfb7be6046d38db561fec56cf9c2
Publikováno v:
PLoS Biology, Vol 22, Iss 3, p e3002537 (2024)
Defective autophagy is linked to proinflammatory diseases. However, the mechanisms by which autophagy limits inflammation remain elusive. Here, we found that the pan-FGFR inhibitor LY2874455 efficiently activated autophagy and suppressed expression o
Externí odkaz:
https://doaj.org/article/1d6e0c25ef9b4958bd6a68a3f329ce6f
Autor:
Xiaozhen Liu, Kewang Sun, Hongjian Yang, Dehomg Zou, Lingli Xia, Kefeng Lu, Xuli Meng, Yongfeng Li
Publikováno v:
Heliyon, Vol 10, Iss 4, Pp e25643- (2024)
Background: Lysosomes are known to have a significant impact on the development and recurrence of breast cancer. However, the association between lysosome-related genes (LRGs) and breast cancer remains unclear. This study aims to explore the potentia
Externí odkaz:
https://doaj.org/article/e2b4a7d6b0c944f29f3e20d8ec03c84c
Autor:
Shiyan Liu, Mutian Chen, Yichang Wang, Yuqing Lei, Ting Huang, Yabin Zhang, Sin Man Lam, Huihui Li, Shiqian Qi, Jia Geng, Kefeng Lu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Sphingolipids are ubiquitous components of membranes and function as bioactive lipid signaling molecules. Here, through genetic screening and lipidomics analyses, we find that the endoplasmic reticulum (ER) calcium channel Csg2 integrates sp
Externí odkaz:
https://doaj.org/article/6d98b328c1c44cfbb8e4e9fae519cea5
Autor:
Yan Wang, Xiaobin Ling, Chong Zhang, Jian Zou, Bingnan Luo, Yongbo Luo, Xinyu Jia, Guowen Jia, Minghua Zhang, Junchao Hu, Ting Liu, Yuanfeiyi Wang, Kefeng Lu, Dan Li, Jinbiao Ma, Cong Liu, Zhaoming Su
Publikováno v:
Molecular Biomedicine, Vol 4, Iss 1, Pp 1-14 (2023)
Abstract SARS-CoV-2 and its variants, with the Omicron subvariant XBB currently prevailing the global infections, continue to pose threats on public health worldwide. This non-segmented positive-stranded RNA virus encodes the multi-functional nucleoc
Externí odkaz:
https://doaj.org/article/0e7267bf39754639bc66cdc375359333
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background Severe lymphedema presents a challenge in terms of treatment due to the significant formation of scar tissue that accompanies it. The aim of this study was to identify intraoperative and preoperative risk factors of severe lymphed
Externí odkaz:
https://doaj.org/article/c44ecfb3b3e8493c8982ace6146d9ae6
Publikováno v:
Molecular Biomedicine, Vol 3, Iss 1, Pp 1-13 (2022)
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the coronavirus disease 2019 (COVID-19) global pandemic. Omicron, a new variant of SARS-CoV-2, has the characteristics of strong transmission and pathogenicity, short in
Externí odkaz:
https://doaj.org/article/d746ee78c7f94768891fb3341d565ddc
Publikováno v:
Petroleum Exploration and Development, Vol 48, Iss 5, Pp 1152-1161 (2021)
To describe the complex phase transformation in the process of depletion exploitation of volatile oil reservoir, four fluid phases are defined, and production and remaining volume of these phases are calculated based on the principle of surface volum
Externí odkaz:
https://doaj.org/article/c4a89e0e0e0a4e8fa5d2004407490a93
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundCarotid free-floating thrombus (CFFT) is a rare but sometimes emergent condition. There has been controversy over the optimal treatment strategy. Emerging evidence suggests that endovascular thrombectomy (EVT) may be an alternative to surge
Externí odkaz:
https://doaj.org/article/d4f65c390cd04ea7923ce6bfc17bb491
Publikováno v:
Cell Death and Disease, Vol 12, Iss 7, Pp 1-11 (2021)
Abstract Lysine crotonylation has been discovered in histone and non-histone proteins and found to be involved in diverse diseases and biological processes, such as neuropsychiatric disease, carcinogenesis, spermatogenesis, tissue injury, and inflamm
Externí odkaz:
https://doaj.org/article/ab2f188392b44109b53687d898bcdfc2