Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Kefeng Dou"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Nonalcoholic fatty liver disease (NAFLD) is the most common liver disorder worldwide. Recent studies show that innate immunity-related signaling pathways fuel NAFLD progression. This study aims to identify potent regulators of innate immunit
Externí odkaz:
https://doaj.org/article/df2852344b9a454aa7a797065172dbee
Autor:
Zhibin Lin, Xuan Zhang, Jianlin Wang, Wei Liu, Qi Liu, Yuchen Ye, Bin Dai, Dongnan Guo, Pengcheng Zhang, Peijun Yang, Ruohan Zhang, Lin Wang, Kefeng Dou
Publikováno v:
Cell Death and Disease, Vol 15, Iss 4, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/78315d1eb3bd426b998227a5428a331f
Autor:
Zhiqiang Fang, Hao Xu, Juanli Duan, Bai Ruan, Jingjing Liu, Ping Song, Jian Ding, Chen Xu, Zhiwen Li, Kefeng Dou, Lin Wang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-15 (2023)
Abstract Nonalcoholic fatty liver disease (NAFLD) which is a leading cause of chronic liver diseases lacks effective treatment. Tamoxifen has been proven to be the first-line chemotherapy for several solid tumors in clinics, however, its therapeutic
Externí odkaz:
https://doaj.org/article/e014e9fcf4224972b1187f95f6493ca3
Autor:
Wenlong Wu, Quancheng Wang, Dandan Han, Jianhui Li, Ye Nie, Dongnan Guo, Long Yang, Kaishan Tao, Xuan Zhang, Kefeng Dou
Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background The prognosis of hepatocellular carcinoma (HCC) is not optimistic. Our study focused on present inflammatory markers, including the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), gamma-glutamyl transpept
Externí odkaz:
https://doaj.org/article/c16a5adf32264faf95c0cc92c4ec4863
Autor:
Zelin Tian, Chen Xu, Peijun Yang, Zhibin Lin, Wenlong Wu, Wenjie Zhang, Jian Ding, Rui Ding, Xuan Zhang, Kefeng Dou
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Hepatocellular carcinoma(HCC) is the sixth most common cancer in the world and is usually caused by viral hepatitis (HBV and HCV), alcoholic, and non-alcoholic fatty liver disease(NAFLD). Viral hepatitis accounts for 80% of HCC cases worldwide. In ad
Externí odkaz:
https://doaj.org/article/00899212d60e4569a9a04386f4a701b7
Autor:
Meng Li, Zhijun Tan, Kuo Zhang, Zhaowei Wang, Lei He, Weina Li, Chuanyang Xu, Jieyu Zhang, Desheng Wang, Kefeng Dou, Ran Zhuang, Boquan Jin, Qiang Hao, Wangqian Zhang, Shuning Wang, Jintao Gu, Lei Shang, Haichuan Su, Yingqi Zhang, Cun Zhang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/d1b9165920ba4fccb35243b894017e8f
Blockade of ARHGAP11A reverses malignant progress via inactivating Rac1B in hepatocellular carcinoma
Autor:
Bin Dai, Xuan Zhang, Runze Shang, Jianlin Wang, Xisheng Yang, Hong Zhang, Qi Liu, Desheng Wang, Lin Wang, Kefeng Dou
Publikováno v:
Cell Communication and Signaling, Vol 16, Iss 1, Pp 1-15 (2018)
Abstract Background The molecular signaling events involving in high malignancy and poor prognosis of hepatocellular carcinoma (HCC) are extremely complicated. Blockade of currently known targets has not yet led to successful clinical outcome. More u
Externí odkaz:
https://doaj.org/article/84365524b81d423ab59a38cc0d181444
Autor:
Geng Zhang, Weijun Qin, Jianlin Yuan, Changsheng Ming, Shuqiang Yue, Zhengcai Liu, Lei Yu, Ming Yu, Xiaokang Gao, Yu Zhou, Longxin Wang, Xiaojian Yang, Kefeng Dou, He Wang
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Objective: To investigate the long-term effect of triple organ transplantation (liver, kidney, and pancreas) in a patient with end-stage liver disease, post chronic hepatitis B, cirrhosis, chronic renal failure, and insulin-dependent diabetes mellitu
Externí odkaz:
https://doaj.org/article/90ac9b5fa0b6422b8fd2df18564b14f0
Autor:
Sheng-Long Ye, Jiamei Yang, Ping Bie, Shuijun Zhang, Xiaoping Chen, Fengyong Liu, Luming Liu, Jie Zhou, Kefeng Dou, Chunyi Hao, Guoliang Shao, Qiang Xia, Yajin Chen, Jijin Yang, Xiaxing Deng, Yunpeng Liu, Yunfei Yuan, Zhiren Fu, Keiko Nakajima, Zhengguang Lv
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background This study aimed to investigate the safety of sorafenib for the treatment of unresectable hepatocellular carcinoma in Chinese patients. Methods A subgroup of 345 Chinese patients from the international database of the Global Inves
Externí odkaz:
https://doaj.org/article/de713bec64504cb39c204547b7a1a1f2
Autor:
Hongchen Ji, Xiao Li, Shuqiang Yue, Junjie Li, Hui Chen, Zhuochao Zhang, Ben Ma, Jing Wang, Meng Pu, Liang Zhou, Chong Feng, Desheng Wang, Juanli Duan, Dengke Pan, Kaishan Tao, Kefeng Dou
Publikováno v:
Cellular Physiology and Biochemistry, Vol 36, Iss 1, Pp 233-249 (2015)
Background: The activation of tissue factor (TF) is one of the major reasons for coagulation dysregulation after pig-to-primate xenotransplantation. Tissue factor pathway inhibitor (TFPI) is the most important inhibitor of TF. Studies have demonstrat
Externí odkaz:
https://doaj.org/article/0bef74c8845d4ec8b08152fb654b4d2d