Zobrazeno 1 - 10
of 251
pro vyhledávání: '"Kefeng, Ding"'
Autor:
Chenqin Le, Chengcheng Liu, Bin Lu, Xinbin Zhou, Yeernaer Jiamaliding, Tian Jin, Siqi Dai, Jun Li, Kefeng Ding, Qian Xiao
Publikováno v:
MedComm, Vol 5, Iss 7, Pp n/a-n/a (2024)
Abstract The association between Hepatitis B virus (HBV) infection and colorectal liver metastases (CRLM) remains ambiguous in current population‐based evidence. To clarify this, we present a retrospective analysis of 5871 colorectal cancer (CRC) p
Externí odkaz:
https://doaj.org/article/73ea73bacf3643b6a025831b82710ab0
Autor:
Jiasheng Xu, Yeting Hu, Jie Zhao, Xiangxing Kong, Sijian Xia, Siqi Dai, Lei Ding, Tongtong Bu, Yue Cao, Manjiao Liu, Linlin Yan, Qian Xiao, Hao Guo, Ying Yuan, Dong Xu, Kefeng Ding
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 3, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/e139a5e1c3214a02960c939be5ffd6b7
Autor:
Jing Sun, Jianhui Zhao, Fangyuan Jiang, Lijuan Wang, Qian Xiao, Fengyan Han, Jie Chen, Shuai Yuan, Jingsun Wei, Susanna C. Larsson, Honghe Zhang, Malcolm G Dunlop, Susan M Farrington, Kefeng Ding, Evropi Theodoratou, Xue Li
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-13 (2023)
Abstract Background The proteome is a major source of therapeutic targets. We conducted a proteome-wide Mendelian randomization (MR) study to identify candidate protein markers and therapeutic targets for colorectal cancer (CRC). Methods Protein quan
Externí odkaz:
https://doaj.org/article/c3278b2d6c4c4125ad2171ac1ae5e07a
Autor:
Xuefeng Fang, Chenhan Zhong, Shanshan Weng, Hanguang Hu, Jian Wang, Qian Xiao, Jianwei Wang, Lifeng Sun, Dong Xu, Xiujun Liao, Caixia Dong, Suzhan Zhang, Jun Li, Kefeng Ding, Ying Yuan
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Rat sarcoma viral oncogene homolog (RAS) gene mutation is a common molecular event in colorectal cancer (CRC). The prognosis of mCRC (metastatic colorectal cancer) patients with RAS mutation is poor and capecitabine and oxaliplati
Externí odkaz:
https://doaj.org/article/647f7799d3cd440ab58ab7ab8867c19c
Autor:
Jingsun Wei, Xiaoxu Ge, Yucheng Qian, Kai Jiang, Xin Chen, Wei Lu, Hang Yang, Dongliang Fu, Yimin Fang, Xinyi Zhou, Qian Xiao, Yang Tang, Kefeng Ding
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionTo better understand the role of immune escape and cancer-associated fibroblasts (CAFs) in colon adenocarcinoma (COAD), an integrative analysis of the tumor microenvironment was performed using a set of 12 immune- and CAF-related genes (I
Externí odkaz:
https://doaj.org/article/e1d3281eba6d482288dd0d3ad2a6a9c5
Autor:
Malcolm Dunlop, Jing Sun, Lijuan Wang, Xue Li, Mingyang Song, Harry Campbell, Evropi Theodoratou, Shuai Yuan, Igor Rudan, Yingshuang Zhu, Kefeng Ding, Jianhui Zhao, Susanna Larsson, Liying Xu, Zhengwei Wan, Konstantinos Tsilidis, Peige Song
Publikováno v:
BMJ Oncology, Vol 2, Iss 1 (2023)
Objective This study aimed to explore the global burden of early-onset cancer based on the Global Burden of Disease (GBD) 2019 study for 29 cancers worldwid.Methods and analysis Incidence, deaths, disability-adjusted life years (DALYs) and risk facto
Externí odkaz:
https://doaj.org/article/3db25d475e1442ef8271c70d98d027b4
Autor:
Sihan Wang, Tian-hao Zhang, Menglong Hu, Kejun Tang, Li Sheng, Mengying Hong, Dongdong Chen, Liubo Chen, Yuan Shi, Jun Feng, Jing Qian, Lifeng Sun, Kefeng Ding, Ren Sun, Yushen Du
Publikováno v:
mSystems, Vol 8, Iss 5 (2023)
ABSTRACT Neuraminidase (NA) is a pivotal surface enzyme and a key therapeutic target in combating the influenza A virus. Its evolution can lead to potential zoonotic transmission, seasonal epidemics, and the emergence of drug-resistant mutants. To ga
Externí odkaz:
https://doaj.org/article/8cbdaca5807e47809dddc79e720604e2
Autor:
Junyi Xin, Mulong Du, Dongying Gu, Kewei Jiang, Mengyun Wang, Mingjuan Jin, Yeting Hu, Shuai Ben, Silu Chen, Wei Shao, Shuwei Li, Haiyan Chu, Linjun Zhu, Chen Li, Kun Chen, Kefeng Ding, Zhengdong Zhang, Hongbing Shen, Meilin Wang
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background The genetic architectures of colorectal cancer are distinct across different populations. To date, the majority of polygenic risk scores (PRSs) are derived from European (EUR) populations, which limits their accurate extrapolation
Externí odkaz:
https://doaj.org/article/7d08ab44d2ae4b52b6212ff1bad5e83b
Autor:
Hang Yang, Xinyi Zhou, Dongliang Fu, Chenqin Le, Jiafeng Wang, Quan Zhou, Xiangrui Liu, Ying Yuan, Kefeng Ding, Qian Xiao
Publikováno v:
Cancer Communications, Vol 43, Iss 1, Pp 42-74 (2023)
Abstract RAS genes are the most frequently mutated oncogenes and play critical roles in the development and progression of malignancies. The mutation, isoform (KRAS, HRAS, and NRAS), position, and type of substitution vary depending on the tissue typ
Externí odkaz:
https://doaj.org/article/e124b06564894234acd92cd10b1aeb29
Autor:
Xuefeng Fang, Ning Zhu, Chenhan Zhong, Liuhong Wang, Jun Li, Shanshan Weng, Hanguang Hu, Caixia Dong, Dan Li, Yongmao Song, Dong Xu, Jianwei Wang, Lifeng Sun, Jian Wang, Zhanhuai Wang, Hongfeng Cao, Xiujun Liao, Ningjuan Yu, Qian Xiao, Mi Mi, Suzhan Zhang, Kefeng Ding, Ying Yuan
Publikováno v:
EClinicalMedicine, Vol 62, Iss , Pp 102123- (2023)
Summary: Background: Microsatellite stable (MSS) and RAS-mutant metastatic colorectal cancer (mCRC) patients are characterized by an immunosuppressive microenvironment and a low response rate to immunotherapy. Chemotherapy and anti-angiogenesis thera
Externí odkaz:
https://doaj.org/article/1b1658cdf06448d39ce387a707d64b2e