Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Kees L M C, Franken"'
Autor:
Linda Voogd, Marjolein van Wolfswinkel, Iman Satti, Andrew D. White, Karin Dijkman, Anele Gela, Krista E. van Meijgaarden, Kees L. M. C. Franken, Julia L. Marshall, Tom H. M. Ottenhoff, Thomas J. Scriba, Helen McShane, Sally A. Sharpe, Frank A. W. Verreck, Simone A. Joosten
Publikováno v:
Vaccines, Vol 12, Iss 10, p 1129 (2024)
Background: Novel vaccines targeting the world’s deadliest pathogen Mycobacterium tuberculosis (Mtb) are urgently needed as the efficacy of the Bacillus Calmette–Guérin (BCG) vaccine in its current use is limited. HLA-E is a virtually monomorphi
Externí odkaz:
https://doaj.org/article/8b29e2c0143946339b940b075e6a6486
Autor:
Nadege Nziza, Deniz Cizmeci, Leela Davies, Edward B. Irvine, Wonyeong Jung, Brooke A. Fenderson, Marwou de Kock, Willem A. Hanekom, Kees L. M. C. Franken, Cheryl L. Day, Tom H. M. Ottenhoff, Galit Alter
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/01712ffb53764dccb83c5798019f95b2
Autor:
Sam Afkhami, Michael R. D’Agostino, Maryam Vaseghi-Shanjani, Madeleine Lepard, Jack X. Yang, Rocky Lai, Margaret Wa Yan Choi, Alexis Chacon, Anna Zganiacz, Kees L. M. C. Franken, Hildegund C. Ertl, Tom H. M. Ottenhoff, Mangalakumari Jeyanathan, Amy Gillgrass, Zhou Xing
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-17 (2023)
Abstract Viral-vectored vaccines are highly amenable for respiratory mucosal delivery as a means of inducing much-needed mucosal immunity at the point of pathogen entry. Unfortunately, current monovalent viral-vectored tuberculosis (TB) vaccine candi
Externí odkaz:
https://doaj.org/article/d2dc7116602d419c9248036c6fe44964
Autor:
Iris N. Pardieck, Tetje C. van der Sluis, Esmé T. I. van der Gracht, Dominique M. B. Veerkamp, Felix M. Behr, Suzanne van Duikeren, Guillaume Beyrend, Jasper Rip, Reza Nadafi, Elham Beyranvand Nejad, Nils Mülling, Dena J. Brasem, Marcel G. M. Camps, Sebenzile K. Myeni, Peter J. Bredenbeek, Marjolein Kikkert, Yeonsu Kim, Luka Cicin-Sain, Tamim Abdelaal, Klaas P. J. M. van Gisbergen, Kees L. M. C. Franken, Jan Wouter Drijfhout, Cornelis J. M. Melief, Gerben C. M. Zondag, Ferry Ossendorp, Ramon Arens
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Vaccination regimens and the number of doses required for optimal immunity and protection are critical factors in the translation of vaccines. Here the authors show administration of a three dose protocol of a single T cell epitope to the SARS-CoV-2
Externí odkaz:
https://doaj.org/article/cd51eadba8a3427fbfa02b68f915520a
Autor:
Nadege Nziza, Wonyeong Jung, Maanasa Mendu, Tina Chen, Ryan P. McNamara, Sarah M. Fortune, Kees L. M. C. Franken, Tom H. M. Ottenhoff, Bryan Bryson, Joseph Ngonzi, Lisa M. Bebell, Galit Alter
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
IntroductionPlacental transfer of maternal antibodies is essential for neonatal immunity over the first months of life. In the setting of maternal HIV infection, HIV-exposed uninfected (HEU) infants are at higher risk of developing severe infections,
Externí odkaz:
https://doaj.org/article/1aefa836d3c6451790963fe3a513e28d
Autor:
Mariateresa Coppola, Fabienne Jurion, Susan J. F. van den Eeden, Hermann Giresse Tima, Kees L. M. C. Franken, Annemieke Geluk, Marta Romano, Tom H. M. Ottenhoff
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-9 (2021)
Abstract Novel tuberculosis (TB)-vaccines preferably should (i) boost host immune responses induced by previous BCG vaccination and (ii) be directed against Mycobacterium tuberculosis (Mtb) proteins expressed throughout the Mtb infection-cycle. Human
Externí odkaz:
https://doaj.org/article/61b3fb75b0394d3298244d9977413a15
Autor:
Gül Kilinç, Kimberley V. Walburg, Kees L. M. C. Franken, Merel L. Valkenburg, Alexandra Aubry, Mariëlle C. Haks, Anno Saris, Tom H. M. Ottenhoff
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
The Mycobacterium avium (Mav) complex accounts for more than 80% of all pulmonary diseases caused by non-tuberculous mycobacteria (NTM) infections, which have an alarming increase in prevalence and vary in different regions, currently reaching 0.3–
Externí odkaz:
https://doaj.org/article/da295c0ae99748708f62ed7e974666b5
Autor:
Nadege Nziza, Deniz Cizmeci, Leela Davies, Edward B. Irvine, Wonyeong Jung, Brooke A. Fenderson, Marwou de Kock, Willem A. Hanekom, Kees L. M. C. Franken, Cheryl L. Day, Tom H. M. Ottenhoff, Galit Alter
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Tuberculosis (TB) is among the leading causes of death worldwide from a single infectious agent, second only to COVID-19 in 2020. TB is caused by infection with Mycobacterium tuberculosis (Mtb), that results either in a latent or active form of disea
Externí odkaz:
https://doaj.org/article/c05fb02d0ae946bc9944946fb009224b
Autor:
Sjoerd H van der Burg, Ramon Arens, Thorbald van Hall, Elham Beyranvand Nejad, Jan Willem Kleinovink, Camilla Labrie, Marit J van Elsas, Hans-Willi Mittrücker, Kees L M C Franken, Sylvia Heink, Thomas Korn
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 4 (2021)
Background High serum interleukin (IL-6) levels may cause resistance to immunotherapy by modulation of myeloid cells in the tumor microenvironment. IL-6 signaling blockade is tested in cancer, but as this inflammatory cytokine has pleiotropic effects
Externí odkaz:
https://doaj.org/article/053008211eae4f6cb776e9ef21bcbc81
Autor:
Mariateresa Coppola, Raquel Villar-Hernández, Krista E. van Meijgaarden, Irene Latorre, Beatriz Muriel Moreno, Esther Garcia-Garcia, Kees L. M. C. Franken, Cristina Prat, Zoran Stojanovic, Maria Luiza De Souza Galvão, Joan-Pau Millet, Josefina Sabriá, Adrián Sánchez-Montalva, Antoni Noguera-Julian, Annemieke Geluk, Jose Domínguez, Tom H. M. Ottenhoff
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
A quarter of the global human population is estimated to be latently infected by Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB). TB remains the global leading cause of death by a single pathogen and ranks among the top-10
Externí odkaz:
https://doaj.org/article/f4efdfe9c8f5406b96af3012dd62beb3