Curdlan, zymosan and a yeast-derived β-glucan reshape tumor-associated macrophages into producers of inflammatory chemo-attractants

Autor: Christiane Rӧsch, Coen Govers, Henk A. Schols, Cor A. Berrevoets, Kees Verhoef, Harry J. Wichers, Reno Debets, Priscilla de Graaff

Publikováno v: Cancer Immunology, Immunotherapy, 70(2), 547-561. Springer Science+Business Media
Cancer Immunology, Immunotherapy, 70(2), 547-561
Cancer Immunology, Immunotherapy
Cancer Immunology, Immunotherapy 70 (2021) 2

Anti-cancer T-cell responses are often halted due to the immune-suppressive micro-environment, in part related to tumor-associated macrophages. In the current study, we assessed indigestible β-glucans (oatβG, curdlan, grifolan, schizophyllan, lenti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c644764a96dd13214028471e55eb3b
https://doi.org/10.1007/s00262-020-02707-4

Update on a Model to Minimize Population Health Loss in Times of Scarce Surgical Capacity During the COVID-19 Crisis and Beyond

Autor: Benjamin Gravesteijn, Eline Krijkamp, Anouk van Alphen, Jan Busschbach, Geert Geleijnse, Isabel Retel Helmrich, Sophie Bruinsma, Céline van Lint, Ernest van Veen, Ewout Steyerberg, Kees Verhoef, Jan van Saase, Hester Lingsma, Rob Baatenburg de Jong

Publikováno v: Value in Health, 25(5), 785-786. Elsevier Ltd.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48504e251e88fda437ffc4ad2230bd8c
https://hdl.handle.net/1887/3564558

Implementation of robotic rectal cancer surgery; a cross-sectional nationwide study

Autor: Louis Giesen, Jan Willem Dekker, Kees Verhoef, Pim Olthof

Publikováno v: European Journal of Surgical Oncology. 49:e51

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::edf256a5e4f6110cbdb213b272bff9d0
https://doi.org/10.1016/j.ejso.2022.11.181

Injection of radiopaque hydrogel at time of lumpectomy improves the target definition for adjuvant radiotherapy

Autor: Margriet A. Sattler, Gerson M. Struik, Gerda M. Verduijn, Kim C. de Vries, Erwin Birnie, Jean-Philippe Pignol, T.M.A.L. Klem, Nienke Hoekstra, Annemarie T. Swaak-Kragten, Kees Verhoef, Alja Schoonbeek, Ali Ghandi

Publikováno v: Radiotherapy & Oncology, 131, 8-13. ELSEVIER IRELAND LTD
Radiotherapy and Oncology, 131, 8-13. Elsevier Ireland Ltd

Background and purpose: During oncoplastic breast-conserving surgery (BCS), the surgical cavity is closed to reduce seroma formation. This makes the radiotherapy target definition using clips challenging, leading to poor inter-observer agreement and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec868d2a228f3e1115e9445580600411
https://hdl.handle.net/1765/113333

FcγRIIB engagement drives agonistic activity of Fc-engineered αOX40 antibody to stimulate human tumor-infiltrating T cells

Autor: Timothy Scott Fisher, Lucia Campos Carrascosa, Valeska de Ruiter, Yannick S. Rakké, Yik Andy Yeung, Pascal Doornebosch, Jie Wei, Jan N. M. IJzermans, Kees Verhoef, Michail Doukas, Karlijn van Loon, Shahram Salek-Ardakani, Wenjing Yang, Keith A. Ching, Lisanne Noordam, Wojciech G. Polak, Patrick P.C. Boor, Dave Sprengers, Irene Ni, Jaap Kwekkeboom, Dirk J. Grünhagen, Adriaan A. van Beek

Publikováno v: Journal for ImmunoTherapy of Cancer, 8(2):000816. BioMed Central Ltd.
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)

BackgroundOX40 (CD134) is a costimulatory molecule of the tumor necrosis factor receptor superfamily that is currently being investigated as a target for cancer immunotherapy. However, despite promising results in murine tumor models, the clinical ef

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d3767bcd457655fb8a2181aa857e8ae
https://pure.eur.nl/en/publications/e71ad835-6f0e-4dad-86a9-c7b601739007