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pro vyhledávání: '"Keerthivasan Jayakumar"'
Autor:
Bhaskar Jayaraman, Siji Jacob Thenumgal, Arvind Ramanathan, Arunmozhi Palaniyandi, Keerthivasan Jayakumar, Gopalakrishnan Mohan Valiathan
Publikováno v:
Asian Pacific Journal of Cancer Prevention. 13:5535-5538
Background: There have been case reports of oral squamous cell carcinoma arising from gingival overgrowth induced by phenytoin - an antiepileptic drug. However, a detailed analysis for the presence of mutations in p53 and ras genes, which are the two
Common docking domain mutation E322K of the ERK2 gene is infrequent in oral squamous cell carcinomas
Autor:
Keerthivasan Jayakumar, Gopalakrishnan Mohan Valiathan, Bhaskar Jayaraman, Arunmozhi Palaniyandi, Hemalatha Ramkumar, Sajeev Bhaskaran, Arvind Ramanathan, Siji Jacob Thenumgal
Publikováno v:
Asian Pacific journal of cancer prevention : APJCP. 13(12)
Background: Mutations in the MAPK (Mitogen Activated Protein Kinase) signaling pathway - EGFR/Ras/ RAF/MEK have been associated with the development of several carcinomas. ERK2, a downstream target of the MAPK pathway and a founding member of the MAP