Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Keerthi Kurma"'
Publikováno v:
Cell Adhesion & Migration, Vol 18, Iss 1, Pp 1-26 (2024)
The current constraints associated with cancer diagnosis and molecular profiling, which rely on invasive tissue biopsies or clinical imaging, have spurred the emergence of the liquid biopsy field. Liquid biopsy involves the extraction of circulating
Externí odkaz:
https://doaj.org/article/b7118325b17245c287999434d5a09777
Early detection of pancreatic cancer by liquid biopsy 'PANLIPSY': a french nation-wide study project
Autor:
Thomas Bardol, Antoine M. Dujon, Valerie Taly, Catherine Dunyach-Remy, Jean-Philippe Lavigne, Bruno Costa-Silva, Keerthi Kurma, Zahra Eslami-S, Laure Cayrefourcq, Cindy Canivet, Fabrice Muscari, Barbara Bournet, Catherine Alix-Panabières
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Pancreatic cancer, predominantly characterized by ductal adenocarcinoma (PDAC) accounts for 90% of cases and is the fourth leading cause of cancer-related deaths globally. Its incidence is notably increasing. This poor prognosis i
Externí odkaz:
https://doaj.org/article/44c5029baad6433f9786b21635522367
Autor:
Thomas Bardol, Zahra Eslami‐S, Doryan Masmoudi, Marie Alexandre, Marie Duboys de Labarre, Angélique Bobrie, Véronique D'Hondt, Séverine Guiu, Keerthi Kurma, Laure Cayrefourcq, William Jacot, Catherine Alix‐Panabières
Publikováno v:
Cancer Medicine, Vol 13, Iss 1, Pp n/a-n/a (2024)
Abstract Background For several years, the AXL tyrosine kinase receptor, a member of the Tyro3‐Axl‐Mer (TAM) family, has been considered a new strategic target in oncology. AXL overexpression is common in solid tumors and is associated with poor
Externí odkaz:
https://doaj.org/article/ccb520c1af084716bac58d6380522524
MMP7 cleavage of amino-terminal CD95 death receptor switches signaling toward non-apoptotic pathways
Autor:
Shoji F. Kenji, Keerthi Kurma, Brigitte Collet, Christelle Oblet, Laure Debure, Carmelo Di Primo, Laëtitia Minder, Franck Vérité, Yannic Danger, Mickael Jean, Aubin Penna, Nicolas Levoin, Patrick Legembre
Publikováno v:
Cell Death and Disease, Vol 13, Iss 10, Pp 1-11 (2022)
Abstract CD95 is a death receptor that can promote oncogenesis through molecular mechanisms that are not fully elucidated. Although the mature CD95 membrane receptor is considered to start with the arginine at position 17 after elimination of the sig
Externí odkaz:
https://doaj.org/article/48a077bb6c494189aee69ecb73c0915b
Autor:
Zahra Eslami-S, Luis Enrique Cortés-Hernández, Ilias Glogovitis, Mafalda Antunes-Ferreira, Silvia D’Ambrosi, Keerthi Kurma, Françoise Garima, Laure Cayrefourcq, Myron G. Best, Danijela Koppers-Lalic, Thomas Wurdinger, Catherine Alix-Panabières
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Background: Platelets are active players in hemostasis, coagulation and also tumorigenesis. The cross-talk between platelets and circulating tumor cells (CTCs) may have various pro-cancer effects, including promoting tumor growth, epithelial-mesenchy
Externí odkaz:
https://doaj.org/article/ce14cb73445c48479eb61a85c74fbe12
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Metastatic progression is the deadliest feature of cancer. Cancer cell growth, invasion, intravasation, circulation, arrest/adhesion and extravasation require specific mechanical properties to allow cell survival and the completion of the metastatic
Externí odkaz:
https://doaj.org/article/a730ac038c2e4f1fadcc4fe9a2047995
Autor:
Lydie Carreres, Marion Mercey-Ressejac, Keerthi Kurma, Julien Ghelfi, Carole Fournier, Olivier Manches, Florent Chuffart, Sophie Rousseaux, Mélanie Minoves, Thomas Decaens, Herve Lerat, Zuzana Macek Jilkova
Publikováno v:
Cells, Vol 11, Iss 13, p 2051 (2022)
Obstructive sleep apnea (OSA) syndrome is characterized by chronic intermittent hypoxia and is associated with an increased risk of all-cause mortality, including cancer mortality. Hepatocellular carcinoma (HCC) is the most common type of liver cance
Externí odkaz:
https://doaj.org/article/b0794a50143741a6b8b24d22a0dd107d
Autor:
Eloïne Bestion, Zuzana Macek Jilkova, Jean-Louis Mège, Marie Novello, Keerthi Kurma, Seyedeh Tayebeh Ahmad Pour, Gilles Lalmanach, Lise Vanderlynden, Lionel Fizanne, Firas Bassissi, Madani Rachid, Jennifer Tracz, Jérôme Boursier, Jérôme Courcambeck, Cindy Serdjebi, Christelle Ansaldi, Thomas Decaens, Philippe Halfon, Sonia Brun
Publikováno v:
Therapeutic Advances in Chronic Disease, Vol 11 (2020)
Background: Hepatic fibrosis is the result of chronic liver injury that can progress to cirrhosis and lead to liver failure. Nevertheless, there are no anti-fibrotic drugs licensed for human use. Here, we investigated the anti-fibrotic activity of GN
Externí odkaz:
https://doaj.org/article/1f2c4f5fc156452bb5c3b4df23efc116
Autor:
Thomas Decaens, Vincent Leroy, Patrice N. Marche, Benoit Busser, Yi Yu, Giovanni Abbadessa, Séyédéh Tayébéh Ahmad Pour, Keerthi Kurma, Ayca Zeybek Kuyucu, Zuzana Macek Jilkova, Gaël S. Roth
Migration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b60ec39d20dbf741a9b6d25f3d0f21
https://doi.org/10.1158/1535-7163.22508710.v1
https://doi.org/10.1158/1535-7163.22508710.v1
Autor:
Thomas Decaens, Vincent Leroy, Patrice N. Marche, Benoit Busser, Yi Yu, Giovanni Abbadessa, Séyédéh Tayébéh Ahmad Pour, Keerthi Kurma, Ayca Zeybek Kuyucu, Zuzana Macek Jilkova, Gaël S. Roth
Supplementary Table 1: IC20 and IC50 values of ARQ 092 and sorafenib in Hep3B, Huh-7, HepG2, PLC/PRF/5 and HR4 cell lines after 48h of exposure; Supplementary Table 2: List of significantly different phospho-kinases from ARQ 092 treated rats compared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f738d7653a11ae714cd8c69b6c74392
https://doi.org/10.1158/1535-7163.22508692
https://doi.org/10.1158/1535-7163.22508692