Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Keerthi Krishnan"'
Autor:
Nandu Babu, Kumar Velappan Nair, Keerthi Krishnan Kallorath, Selvakumar Arulprakasam, Sudeep Ullattil
Publikováno v:
Materials Research, Vol 27 (2024)
Cryogenic treatment enhances the properties of cutting tools. This study investigates the effects of shallow and deep cryogenic treatments to TiAlSiN coated tungsten carbide tool used in end milling of maraging steel C300. Experiments are conducted i
Externí odkaz:
https://doaj.org/article/7358cfeaf83f4becb175e70f2b683500
Autor:
Kevin Luxem, Jennifer J Sun, Sean P Bradley, Keerthi Krishnan, Eric Yttri, Jan Zimmermann, Talmo D Pereira, Mark Laubach
Publikováno v:
eLife, Vol 12 (2023)
Recently developed methods for video analysis, especially models for pose estimation and behavior classification, are transforming behavioral quantification to be more precise, scalable, and reproducible in fields such as neuroscience and ethology. T
Externí odkaz:
https://doaj.org/article/aaa610c8aa954e8b9ecab0298ba34acc
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11262 (2022)
In the current study, we introduce an integrative machine learning strategy for the autonomous molecular design of protein kinase inhibitors using variational autoencoders and a novel cluster-based perturbation approach for exploration of the chemica
Externí odkaz:
https://doaj.org/article/308651b4301141b19fbcaf9259dd1e40
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11542 (2022)
In this study, we performed all-atom MD simulations of RBD–ACE2 complexes for BA.1, BA.1.1, BA.2, and BA.3 Omicron subvariants, conducted a systematic mutational scanning of the RBD–ACE2 binding interfaces and analysis of electrostatic effects. T
Externí odkaz:
https://doaj.org/article/e9442ccb88c3476fa5c1faef1e53087e
Publikováno v:
Biomolecules, Vol 12, Iss 7, p 964 (2022)
In this study, we combined all-atom MD simulations, the ensemble-based mutational scanning of protein stability and binding, and perturbation-based network profiling of allosteric interactions in the SARS-CoV-2 spike complexes with a panel of cross-r
Externí odkaz:
https://doaj.org/article/052867bf489248abade91a85da2a1652
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 8, p 4376 (2022)
In this study, we combine all-atom MD simulations and comprehensive mutational scanning of S-RBD complexes with the angiotensin-converting enzyme 2 (ACE2) host receptor in the native form as well as the S-RBD Delta and Omicron variants to (a) examine
Externí odkaz:
https://doaj.org/article/d7aa3b4f23f042b8b033f20d2f4d9ba9
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Rett syndrome is associated with impaired synaptic connectivity beginning in early development. Here the authors show in female mice heterozygous forMecp2, a model of Rett syndrome, that during adulthood, auditory cortex plasticity associated with a
Externí odkaz:
https://doaj.org/article/2b5895d8e4a14e788bb12e1a4e851f72
Publikováno v:
In Materials Today Communications June 2024 39
Publikováno v:
PLoS ONE, Vol 3, Iss 11, p e3621 (2008)
Spt5 is a conserved essential protein that represses or stimulates transcription elongation in vitro. Immunolocalization studies on Drosophila polytene chromosomes suggest that Spt5 is associated with many loci throughout the genome. However, little
Externí odkaz:
https://doaj.org/article/1fa3cab4731641cc88ff5e7eb4c7e537
Publikováno v:
In Surface & Coatings Technology 15 December 2023 474