Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Keerthana Balamurugan"'
Autor:
Keerthana Balamurugan, Raghavender Medishetti, Pallavi Rao, Rahul Varma K, Kiranam Chatti, Kishore V.L. Parsa
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101819- (2022)
Summary: In this report, we describe an approach to generate a zebrafish larval model of lipid accumulation that can be used as an in vivo system to study hyperlipidemic conditions such as atherosclerosis. Furthermore, we detail steps on staining tec
Externí odkaz:
https://doaj.org/article/b5a51f5e18544b4a9546639a20023c5f
Autor:
Raghavender Medishetti, Keerthana Balamurugan, Krishnaveni Yadavalli, Rita Rani, Aarti Sevilimedu, Anil Kumar Challa, Kishore Parsa, Kiranam Chatti
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101779- (2022)
Summary: The application of CRISPR has greatly facilitated genotype-phenotype studies of human disease models. In this protocol, we describe CRISPR-Cas9-induced gene knockout in zebrafish, utilizing purified Cas9 protein and in vitro-transcribed sgRN
Externí odkaz:
https://doaj.org/article/324fb06899d64991bbddeedcf320850e
Autor:
Keerthana Balamurugan, Raghavender Medishetti, Jyothi Kotha, Parameshwar Behera, Kanika Chandra, Vijay Aditya Mavuduru, Manjunath B. Joshi, Ramesh Samineni, Madhumohan R. Katika, Writoban Basu Ball, Manjunatha Thondamal, Anil Challa, Kiranam Chatti, Kishore V.L. Parsa
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103766- (2022)
Summary: Infiltration of arterial intima by foamy macrophages is a hallmark of early atherosclerotic lesions. Here, we investigated the potential role of Ser/Thr phosphatase PHLPP1 in foam cell development. PHLPP1 levels were elevated in OxLDL-expose
Externí odkaz:
https://doaj.org/article/fe4f6b2971f64ef89092d79c791f559d
Publikováno v:
Journal of Medical Engineering & Technology. 46:318-334
A wound is a trauma caused by some adverse external or blunt forces that can damage the body tissues. Wound healing is a complex process that occurs post-injury which involves the revamping of the structure and function of damaged tissues. Scaffolds
Autor:
Keerthana Balamurugan, Kanika Chandra, S. Sai Latha, M. Swathi, Manjunath B. Joshi, Parimal Misra, Kishore V.L. Parsa
Publikováno v:
Drug discovery today. 27(10)
That reversible protein phosphorylation by kinases and phosphatases occurs in metabolic disorders is well known. Various studies have revealed that a multi-faceted and tightly regulated phosphatase, pleckstrin homology domain leucine-rich repeat prot