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Autor:
Rafaela Scandolara, Charles Bruker, Keenan Hogan, Molly Mercedes Ryan, Ariel Joy Lipat, Jacques Galipeau, Mihir Patel, Rahul Das, Raghavan Chinnadurai
Publikováno v:
Transplant Cell Ther
BACKGROUND: Ruxolitinib is a JAK2/JAK1 inhibitor which blocks inflammatory JAK-STAT signaling pathway. Ruxolitinib has been demonstrated to be effective in the treatment of steroid-resistant acute Graft vs Host Disease (GvHD). Ruxolitinib’s effect