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of 8
pro vyhledávání: '"Keeley Murphy"'
Autor:
Christina J. Vanhinsbergh, Angela Criscuolo, Jennifer N. Sutton, Keeley Murphy, Andrew J. K. Williamson, Ken Cook, Mark J. Dickman
Publikováno v:
Analytical Chemistry. 94:7339-7349
Large RNA including mRNA (mRNA) has emerged as an important new class of therapeutics. Recently, this has been demonstrated by two highly efficacious vaccines based on mRNA sequences encoding for a modified version of the SARS-CoV-2 spike protein. Th
Autor:
Surendra Bansal, Jun Qu, Ming Zhang, Xue Wang, Keeley Murphy, Luca Ferrari, Shaolian Zhou, Yang Qu, Shichen Shen, Bo An, John M. Canty, Rebeccah F. Young, Debadeep Bhattacharyya, Jonathan L. Josephs, Yuan-Ju Chen, Wei Fu, Faye Vazvaei, Joseph P. Balthasar
Publikováno v:
Analytical Chemistry. 90:1870-1880
For LC-MS-based targeted quantification of biotherapeutics and biomarkers in clinical and pharmaceutical environments, high sensitivity, high throughput, and excellent robustness are all essential but remain challenging. For example, though nano-LC-M
Autor:
Keeley Murphy, Wilson Z. Shou, Harold N. Weller, Tatyana Zvyaga, Jun Zhang, Ying Li, Cheryl Ferraro, Marianne Vath
Publikováno v:
Rapid Communications in Mass Spectrometry. 27:731-737
RATIONALE Multiplexed liquid chromatography (LC) coupled with multiple-injection-chromatogram acquisition has emerged as the method of choice for high-speed discovery bioanalysis, because it significantly reduces injection-to-injection cycle time whi
Publikováno v:
Bioanalysis. 4:1013-1024
Background: High-throughput screening with LC–MS has been routinely implemented to various degrees throughout the entire drug-discovery process. One of the major advantages of utilizing LC–MS earlier at the lead discovery stage is reducing the co
Autor:
Hendrik W. Brinks, Craig M. Jensen, Sesha S. Srinivasan, Didier Blanchard, Bjørn C. Hauback, Keeley Murphy
Publikováno v:
Journal of Alloys and Compounds. 376:215-221
NaAlH4, Na3AlH6 and NaH samples with Ti additives have been investigated by synchrotron X-ray diffraction and neutron diffraction. Directly after ball milling there are no signs of any Ti-containing phases, and the unit-cell dimensions of NaAlH4, Na3
Autor:
Jun, Zhang, Marianne, Vath, Cheryl, Ferraro, Ying, Li, Keeley, Murphy, Tatyana, Zvyaga, Harold, Weller, Wilson, Shou
Publikováno v:
Rapid communications in mass spectrometry : RCM. 27(7)
Multiplexed liquid chromatography (LC) coupled with multiple-injection-chromatogram acquisition has emerged as the method of choice for high-speed discovery bioanalysis, because it significantly reduces injection-to-injection cycle time while maintai
Publikováno v:
Bioanalysis. 4(11)
Background: Laser diode thermal desorption (LDTD) is a relatively new sample introduction interface for MS. Analysis times are short as the technique does not require time-consuming separation steps, such as conventional HPLC, thus saving on the use
Autor:
Zhaohui Wang, Craig M. Jensen, Keeley Murphy, Xue-Qin Gu, Walter P. Niemczura, Michael R. Eberhard, Kristin K. Kumashiro, Dalin Sun, Sesha Sai Raman
Values for the ∆H ‡ of dehydrogenation NaAlH4 to Na3AlH6/Al and Na3AlH6 to NaH/Al and the reverse hydrogenation reactions have been determined through kinetic studies of 2 mol % Ti and Zr doped hydride. We find that the experimentally determined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c6f1197204d284212c721b3f8ca82f8
https://doi.org/10.2172/890543
https://doi.org/10.2172/890543