Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Keefe Chng"'
Autor:
Peining Tao, Stacey Conarello, Thomas P. Wyche, Nanyan Rena Zhang, Keefe Chng, John Kang, Theodore R. Sana
Publikováno v:
Metabolites, Vol 14, Iss 3, p 159 (2024)
Type 2 diabetes (T2D) is a global public health issue characterized by excess weight, abdominal obesity, dyslipidemia, hyperglycemia, and a progressive increase in insulin resistance. Human population studies of T2D development and its effects on sys
Externí odkaz:
https://doaj.org/article/50ab0f0e80484fc1978aed52a6d43461
Autor:
Guodong Zhang, Xiaoli Wang, Tzu-Yang Chung, Weiwei Ye, Lauren Hodge, Likun Zhang, Keefe Chng, Yong-Fu Xiao, Yixin Jim Wang
Publikováno v:
BMC Gastroenterology, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Multiple murine models of nonalcoholic fatty liver disease/steatohepatitis (NAFLD/NASH) have been established by using obesogenic diets and/or chemical induction. MS-NASH mouse (formally FATZO) is a spontaneously developed dysmeta
Externí odkaz:
https://doaj.org/article/9dc6cd1899d248689a66509ec002d3f7
Autor:
Camilo Libedinsky, Rosa So, Zhiming Xu, Toe K Kyar, Duncun Ho, Clement Lim, Louiza Chan, Yuanwei Chua, Lei Yao, Jia Hao Cheong, Jung Hyup Lee, Kulkarni Vinayak Vishal, Yongxin Guo, Zhi Ning Chen, Lay K Lim, Peng Li, Lei Liu, Xiaodan Zou, Kai K Ang, Yuan Gao, Wai Hoe Ng, Boon Siew Han, Keefe Chng, Cuntai Guan, Minkyu Je, Shih-Cheng Yen
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165773 (2016)
Individuals with tetraplegia lack independent mobility, making them highly dependent on others to move from one place to another. Here, we describe how two macaques were able to use a wireless integrated system to control a robotic platform, over whi
Externí odkaz:
https://doaj.org/article/2db6d9ccaaad49aea7ca6359da005a5e
Autor:
Xiaoli Wang, Guodong Zhang, Tzu-Yang Chung, Yong-Fu Xiao, Yixin Jim Wang, Li-Kun Zhang, Lauren Hodge, Weiwei Ye, Keefe Chng
Publikováno v:
BMC Gastroenterology
BMC Gastroenterology, Vol 20, Iss 1, Pp 1-13 (2020)
BMC Gastroenterology, Vol 20, Iss 1, Pp 1-13 (2020)
Background Multiple murine models of nonalcoholic fatty liver disease/steatohepatitis (NAFLD/NASH) have been established by using obesogenic diets and/or chemical induction. MS-NASH mouse (formally FATZO) is a spontaneously developed dysmetabolic str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2ae3e3a73efecd668c661b1fd088ac7
http://europepmc.org/articles/PMC7560288
http://europepmc.org/articles/PMC7560288
Autor:
Yong-Fu Xiao, Haishan Jiang, Jiaping Zhang, Yanqin Ji, Qian Jin, Davey Wang, Weihua Song, Mengnan Jiang, Chen Yang, Jiajun Gao, Dunwei Zhang, Yixin Wang, Weiwei Ye, Keefe Chng, Feng Shi, Xiaoyu Zhang, Xiaoli Wang
Publikováno v:
Diabetes. 69
Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome as an arising health issue globally. Obesity and diabetes seem coherent with high NAFLD occurrence. Currently, its underlying mechanism of cause and progressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::009262b2656b0f1e23cecdb11f084894
https://doi.org/10.2337/db20-1826-p
https://doi.org/10.2337/db20-1826-p
Publikováno v:
Diabetes. 69
MS-NASH mouse is a leptin pathway intact model of spontaneous metabolic diseases. Our previous work developed a nonalcoholic steatohepatitis (NASH) model in MS-NASH mice fed with western diet and fructose drinking water (WDF). This study showed aggra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f0158bf928911774003f25fe700b81d
https://doi.org/10.2337/db20-1829-p
https://doi.org/10.2337/db20-1829-p
Autor:
Victoria Plamadeala Johnson, Emanuel Zycband, Stacey Conarello, Yonghua Zhu, David E. Kelley, Michael Staup, Jin Shang, Mark D. Erion, Dan Xie, Keefe Chng, Gladys Arreaza, Stephen F. Previs, Liangsu Wang, Margaret van Heek, Diane Levitan, Yixin Wang, Karni Schlessinger, Sandra C. Souza, Ying Chen, Franklin Liu
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 312:E235-E243
Insulin resistance and diabetes can develop spontaneously with obesity and aging in rhesus monkeys, highly similar to the natural history of obesity, insulin resistance, and progression to type 2 diabetes in humans. The current studies in obese rhesu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea6be096903d99992ef951ec8277fde
https://doi.org/10.1152/ajpendo.00398.2016
https://doi.org/10.1152/ajpendo.00398.2016
Autor:
Gary W. Cline, Leigh Goedeke, Gerald I. Shulman, Kitt Falk Petersen, Mario Kahn, Valle Montalvo Romeral, Sylvie Dufour, Keefe Chng, Xian-Man Zhang, Gina M. Butrico
Publikováno v:
Diabetes. 68
NAFLD is estimated to affect up to one third of the general population and is a major predisposing factor in the pathogenesis of hepatic insulin resistance, NASH, and T2D. While weight loss is highly effective at reversing NAFLD, insulin resistance a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31335b43ad4a6f77dda4553ee0d93654
https://doi.org/10.2337/db19-19-or
https://doi.org/10.2337/db19-19-or
Publikováno v:
Diabetes. 68
Carbon Tetrachloride (CCl4) is a common hepatotoxin used in liver injury and fibrosis animal models, but it is rare to observe obesity and liver fat accumulation in CCl4-induced liver fibrosis models since weight loss is also provoked. Nonalcoholic S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7830a68297565f23665e9dd1742b857c
https://doi.org/10.2337/db19-303-lb
https://doi.org/10.2337/db19-303-lb
Autor:
Liang Peng, Xian-Man Zhang, Sylvie Dufour, Valle Montalvo-Romeral, Paul Kievit, Keefe Chng, Rachel J. Perry, Gina M. Butrico, Gary W. Cline, Kitt Falk Petersen, Leigh Goedeke, Gerald I. Shulman
Publikováno v:
Sci Transl Med
NAFLD is estimated to affect up to one third of the general population and is a major predisposing factor in the pathogenesis of hepatic insulin resistance, NASH, and T2D. While weight loss is highly effective at reversing NAFLD, insulin resistance a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a915afff71c5a951abd67ec1b5eaf1cd
https://pubmed.ncbi.nlm.nih.gov/31578240
https://pubmed.ncbi.nlm.nih.gov/31578240