Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Kee Woong Kwon"'
Autor:
Eunsol Choi, Hong-Hee Choi, Kee Woong Kwon, Hagyu Kim, Ji-Hwan Ryu, Jung Joo Hong, Sung Jae Shin
Publikováno v:
PLoS Pathogens, Vol 20, Iss 8, p e1012500 (2024)
NADPH oxidase 2 (NOX2) is an enzyme responsible for generating reactive oxygen species, primarily found in phagocytes. Chronic Granulomatous Disease (CGD), along with bacterial infections such as Mycobacterium tuberculosis (Mtb), is a representative
Externí odkaz:
https://doaj.org/article/df04cb2610b94d89b1390e6187907ece
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-12 (2024)
Abstract The quest for effective and enhanced multiantigenic tuberculosis (TB) subunit vaccine necessitates the induction of a protective pathogen-specific immune response while circumventing detrimental inflammation within the lung milieu. In line w
Externí odkaz:
https://doaj.org/article/2e3c0bfa162e444890aabef153c4e7a5
Publikováno v:
Vaccine: X, Vol 15, Iss , Pp 100400- (2023)
The global emergency of unexpected pathogens, exemplified by SARS-CoV-2, has emphasized the importance of vaccines in thwarting infection and curtailing the progression of severe disease. The scourge of tuberculosis (TB), emanating from the Mycobacte
Externí odkaz:
https://doaj.org/article/c38b59be13f94071bc6212bddc4c687e
Autor:
Ju Mi Lee, Jiyun Park, Steven G Reed, Rhea N Coler, Jung Joo Hong, Lee-Han Kim, Wonsik Lee, Kee Woong Kwon, Sung Jae Shin
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 808-832 (2022)
Mycobacterium avium complex (MAC) causing pulmonary disease in humanshas emerged worldwide. Thus, effective strategies simultaneously aiming to prevent MAC infection and accelerate therapeutic efficacy are required. To this end, subunit vaccine-induc
Externí odkaz:
https://doaj.org/article/8e3834bd4ef94d8ba1c038d19f6dfc4c
Autor:
Kee Woong Kwon, Michel de Jesús Aceves-Sánchez, Cristian Alfredo Segura-Cerda, Eunsol Choi, Helle Bielefeldt-Ohmann, Sung Jae Shin, Mario Alberto Flores-Valdez
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Previously, we reported that a hygromycin resistant version of the BCGΔBCG1419c vaccine candidate reduced tuberculosis (TB) disease in BALB/c, C57BL/6, and B6D2F1 mice infected with Mycobacterium tuberculosis (Mtb) H37Rv. Here, the second-g
Externí odkaz:
https://doaj.org/article/7166e761db4248398a4fcf3737c84427
Autor:
Tae Gun Kang, Kee Woong Kwon, Kyungsoo Kim, Insuk Lee, Myeong Joon Kim, Sang-Jun Ha, Sung Jae Shin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Viral coinfection alongside mycobacterium tuberculosis (Mtb) infection may lead to immune complications or interference with immune responses. Here the authors show that in mice infected with Mtb and LCMV virus the specific TH1 response to MTb is red
Externí odkaz:
https://doaj.org/article/e9f3bc112bd94dec938789f5b164586c
Autor:
Yeeun Bak, Sang Chul Park, Dahee Shim, Yura Ha, Jumi Lee, Hongmin Kim, Kee Woong Kwon, Joo-Heon Yoon, Sung Jae Shin
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 2546-2561 (2021)
Accumulating evidence suggests that two chronic respiratory diseases, nontuberculous mycobacterium (NTM)-pulmonary disease (PD) and allergic asthma, are frequently present together and that they likely influence the disease development and progressio
Externí odkaz:
https://doaj.org/article/c343d14bce414a6bae191a55b8284efc
Autor:
Jaehun Park, Hongmin Kim, Kee Woong Kwon, Hong-Hee Choi, Soon Myung Kang, Jung Joo Hong, Sung Jae Shin
Publikováno v:
Virulence, Vol 11, Iss 1, Pp 430-445 (2020)
Toll-like receptors (TLRs) play critical roles in the innate recognition of Mycobacterium tuberculosis (Mtb) by host immune cells. However, controversy has arisen regarding the role of TLR4 in determining the outcomes of Mtb infection. To address thi
Externí odkaz:
https://doaj.org/article/c6d1f9554ee64768ba17f5642f5efff8
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Our group recently identified InsB, an ESAT-6-like antigen belonging to the Mtb9.9 subfamily within the Esx family, in the Mycobacterium tuberculosis Korean Beijing strain (Mtb K) via a comparative genomic analysis with that of the reference Mtb H37R
Externí odkaz:
https://doaj.org/article/73ace92842994968bafdd1fcb620e124
Autor:
Han-Gyu Choi, Kee Woong Kwon, Seunga Choi, Yong Woo Back, Hye-Soo Park, Soon Myung Kang, Eunsol Choi, Sung Jae Shin, Hwa-Jung Kim
Publikováno v:
Vaccines, Vol 8, Iss 2, p 300 (2020)
The antigen-specific Th17 responses in the lungs for improved immunity against Mycobacterium tuberculosis (Mtb) infection are incompletely understood. Tuberculosis (TB) vaccine candidate HSP90-ESAT-6 (E6), given as a Bacillus Calmette-Guérin (BCG)-p
Externí odkaz:
https://doaj.org/article/9c5433a28cfd44249160e3304ca02d4b