Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Kee K, Kim"'
Publikováno v:
Animal Cells and Systems, Vol 28, Iss 1, Pp 315-325 (2024)
Exposure to toxic molecules from food or oral medications induces toxicity in colon cells that cause various human diseases; however, in vitro monitoring systems for colon cell toxicity are not well established. Stress granules are nonmembranous foci
Externí odkaz:
https://doaj.org/article/173dd90d3064496daa11681ff051a318
Autor:
Namjoon Cho, Yong-Eun Kim, Yunkyeong Lee, Dong Wook Choi, Chungoo Park, Jung-Hwan Kim, Keun Il Kim, Kee K. Kim
Publikováno v:
Animal Cells and Systems, Vol 28, Iss 1, Pp 261-271 (2024)
ABSTRACTThe ring finger protein 113A (RNF113A) serves as an E3 ubiquitin ligase and a subunit of the spliceosome. Mutations in the RNF113A gene are associated with X-linked trichothiodystrophy (TTD). However, the cellular roles of RNF113A remain larg
Externí odkaz:
https://doaj.org/article/0536be66c84a4b299ace99c6d764f7a5
Publikováno v:
PLoS Pathogens, Vol 20, Iss 7, p e1012295 (2024)
The emergence of drug-resistant Mycobacterium tuberculosis (M.tb) has led to the development of novel anti-tuberculosis (anti-TB) drugs. Common methods for testing the efficacy of new drugs, including two-dimensional cell culture models or animal mod
Externí odkaz:
https://doaj.org/article/49fe3968931f4ed397e748a636b88227
Publikováno v:
Animal Cells and Systems, Vol 27, Iss 1, Pp 171-179 (2023)
ABSTRACTChloromethylisothiazolinone (CMIT), a humidifier disinfectant, is known to be toxic to the respiratory system. While the toxic effect of CMIT on the lungs has been widely investigated, its effect on the skin is well unknown. In this study, we
Externí odkaz:
https://doaj.org/article/a886badd3bf84f77b579b5c7b9824f3f
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-18 (2023)
Abstract Alternative pre-mRNA splicing is a critical mechanism that generates multiple mRNA from a single gene, thereby increasing the diversity of the proteome. Recent research has highlighted the significance of specific splicing isoforms in cellul
Externí odkaz:
https://doaj.org/article/ebea55f7fa264153b61100dcb361e76f
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 269, Iss , Pp 115755- (2024)
Under various cellular stress conditions, including exposure to toxic chemicals, RNA-binding proteins (RBPs), including Ras GTPase-activating protein-binding protein 1 (G3BP1), aggregate and form stress granule complexes, which serve as hallmarks of
Externí odkaz:
https://doaj.org/article/0913fca989c948a693165e5c23325a95
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 4, Pp 755-766 (2023)
Abstract Cells produce multiple mRNAs through alternative splicing, which ensures proteome diversity. Because most human genes undergo alternative splicing, key components of signal transduction pathways are no exception. Cells regulate various signa
Externí odkaz:
https://doaj.org/article/b408315b36ad4dc69cd7574e4aab8129
Autor:
Haesoo Jung, Damin Jung, Jaehoon Lee, Woojin Ki, Jung-Min Lee, Eun-Mi Kim, Myoung Soo Nam, Kee K. Kim
Publikováno v:
Animal Cells and Systems, Vol 26, Iss 5, Pp 232-242 (2022)
Whey protein (WP) in milk shows physiologically active functions such as cholesterol control and immune system strengthening. In this study, we performed hydrolysis and peptide polarity fractionation to enhance the efficacy and diversity of its physi
Externí odkaz:
https://doaj.org/article/c8e1997661324728b2601fc1eced8e4d
Publikováno v:
Animal Cells and Systems, Vol 26, Iss 4, Pp 158-165 (2022)
Melittin is a major component of bee venom; it is widely used in traditional medicine because of its therapeutic effects, such as anti-inflammatory effects. However, melittin has limited medical applications owing to its adverse effects, such as high
Externí odkaz:
https://doaj.org/article/ca89e649d427464e9869c409dbb2e8c2
Autor:
Namjoon Cho, Jaegeon Joo, Sunkyung Choi, Bu-Gyeong Kang, Andrew J. Lee, So-Yeon Youn, Su-Hyung Park, Eun-Mi Kim, Eliezer Masliah, Yuji Ko, Sun-Shin Cha, Inkyung Jung, Kee K. Kim
Publikováno v:
Heliyon, Vol 9, Iss 3, Pp e14039- (2023)
Several studies have identified mutations in neuroprotective genes in a few cases of Parkinson's disease (PD); however, the role of alternative splicing changes in PD remains unelucidated. Based on the transcriptome analysis of substantia nigra (SN)
Externí odkaz:
https://doaj.org/article/4b9006d5a8814af790553007ee3c8493