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of 38
pro vyhledávání: '"Kee Hun Do"'
Publikováno v:
Toxins, Vol 7, Iss 10, Pp 4111-4130 (2015)
Medicinal herbs have been increasingly used for therapeutic purposes against a diverse range of human diseases worldwide. Moreover, the health benefits of spices have been extensively recognized in recent studies. However, inevitable contaminants, in
Externí odkaz:
https://doaj.org/article/8e15465bf1a3475c8e90622b487892d8
Publikováno v:
Oncotarget
Epithelial ovarian cancer (EOC) remains the most lethal gynecologic malignancy in developed countries. Chronic endogenous sterile pro-inflammatory responses are strongly linked to EOC progression and chemoresistance to anti-cancer therapeutics. In th
Publikováno v:
The Journal of Immunology. 197:1415-1424
In response to ulcerative mucosal injuries, intestinal epithelial restitution is a critical event in the early defense against harmful attacks by luminal Ags. Based on the assumption that epithelial NAG-1 is an endogenous regulator of ulcerative stre
Publikováno v:
Oncotarget
Foodborne aflatoxin B1 (AFB1) and ochratoxin A (OTA) cause genotoxic injury and subsequent tumor formation. As a biomarker of oncogenic stimulation by genotoxic mycotoxins, p53-triggered Mdm2 was assessed in intestinal cancer cells. AFB1 increased Md
Publikováno v:
Toxins
Toxins, Vol 7, Iss 10, Pp 4111-4130 (2015)
Toxins, Vol 7, Iss 10, Pp 4111-4130 (2015)
Medicinal herbs have been increasingly used for therapeutic purposes against a diverse range of human diseases worldwide. Moreover, the health benefits of spices have been extensively recognized in recent studies. However, inevitable contaminants, in
Autor:
Hye Jin Choi, Juil Kim, Jiyeon Park, Seong-Hwan Park, Chang Gyu Oh, Bo Gyoung Song, Jae-Hong Park, Kee Hun Do, Seungjoon Lee, Yuseok Moon
Publikováno v:
Journal of Life Science. 24:1339-1344
Inflammatory bowel disease is an immune disorder associated with chronic mucosal inflammation and severe ulceration in the gastrointestinal tract. Antibodies against proinflammatory cytokines, including TNFα, are currently used as promising therapeu
Autor:
Hwi-Gon Kim, Yong Sik Kim, Seong-Hwan Park, Kee Hun Do, Seungjoon Lee, Chang Gyu Oh, Yuseok Moon, Soon Cheol Ahn, Jiyeon Park, Juil Kim, Hye Jin Choi, Young Chul Park
Publikováno v:
Toxicology Letters. 231:1-8
Carrageenan (CGN), a widely used food additive, has been shown to injure the epithelial barrier in animal models. This type of damage is a clinical feature of inflammatory bowel disease (IBD) in humans. In the present study, the effects of CGN on pro
Publikováno v:
The Journal of Immunology. 190:6501-6510
Although the activation of B cells in the gastrointestinal tract is of great importance in the context of immunity to pathogens and mucosal inflammatory diseases, little is known about the mechanisms responsible for the local activation of B cells in
Publikováno v:
Infection and Immunity. 81:1860-1869
Intestinal epithelial activation of nuclear factor kappa B (NF-κB) exerts both detrimental and beneficial functions in response to various luminal insults, including ones associated with mucosa-associated pathogens. Gastrointestinal infection with e
Autor:
Chang Gyu Oh, Yuseok Moon, Juil Kim, Hyun-Hong Kim, Kee Hun Do, Hye Jin Choi, Seong-Hwan Park
Publikováno v:
Biochemical Pharmacology. 84:513-521
NF-κB expression and activity are strictly regulated in gut epithelia to prevent overstimulation of pro-inflammatory responses following exposure to commensal bacteria. The effects of epithelial EGR-1 on responses to bacterial NF-κB-activating lipo