Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Kee Ho Lee"'
Autor:
Yuna Shin, Wonhee Jung, Mi-Yeon Kim, Dongjo Shin, Geun Hee Kim, Chun Ho Kim, Sun-Hoo Park, Eung-Ho Cho, Dong Wook Choi, Chul Ju Han, Kee Ho Lee, Sang-Bum Kim, Hyun Jin Shin
Publikováno v:
Cancers, Vol 14, Iss 23, p 5850 (2022)
G protein–coupled receptors (GPCRs) are a diverse family of cell surface receptors implicated in various physiological functions, making them common targets for approved drugs. Many GPCRs are abnormally activated in cancers and have emerged as ther
Externí odkaz:
https://doaj.org/article/f45decb00a7546f5af33d05de72c1a75
Autor:
Susoma Jannat, Anand Balupuri, Md Yousof Ali, Seong Su Hong, Chun Whan Choi, Yun-Hyeok Choi, Jin-Mo Ku, Woo Jung Kim, Jae Yoon Leem, Ju Eun Kim, Abinash Chandra Shrestha, Ha Neul Ham, Kee-Ho Lee, Dong Min Kim, Nam Sook Kang, Gil Hong Park
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 2, Pp 1-18 (2019)
Alzheimer’s disease: Promising therapeutic compounds found in plants Compounds extracted from bracken fern block the activity of three enzymes associated with Alzheimer’s disease (AD). Because AD is a complex and multifactorial disease, a multita
Externí odkaz:
https://doaj.org/article/5ae3be2dc39f46c2984bc757d6b01c33
Autor:
Eun‐Ran Park, Sang‐Bum Kim, Jee‐San Lee, Yang‐Hyun Kim, Dong‐Hyoung Lee, Eung‐Ho Cho, Sun‐Hoo Park, Chul Ju Han, Bu‐Yeo Kim, Dong Wook Choi, Young Do Yoo, Ami Yu, Jae Won Lee, Ja June Jang, Young Nyun Park, Kyung‐Suk Suh, Kee‐Ho Lee
Publikováno v:
Cancer Medicine, Vol 6, Iss 4, Pp 749-760 (2017)
Abstract Alterations in mitochondrial respiration contribute to the development and progression of cancer via abnormal biogenesis, including generation of reactive oxygen species. Ubiquinol–cytochrome c reductase hinge protein (UQCRH) consists of t
Externí odkaz:
https://doaj.org/article/88af73ebc6d7459488be31942aa346fe
Autor:
Su-Jae Lee, Kee-Ho Lee, Haekwon Kim, Young-Hyun Choi, Changil Kim, Sang-Gu Hwang, In-Chul Park, Soon-Young Choi, Min-Jung Kim
Exposure of cells to ionizing radiation induces activation of multiple signaling pathways that play critical roles in determining cell fate. However, the molecular basis for cell death or survival signaling in response to radiation is unclear at pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31747c826fb1fdc05d908824a772a3f0
https://doi.org/10.1158/1541-7786.c.6541786.v1
https://doi.org/10.1158/1541-7786.c.6541786.v1
Supplementary Figures S1-S4 from c-Src-p38 Mitogen-Activated Protein Kinase Signaling Is Required for Akt Activation in Response to Ionizing Radiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1514378c8df2467ea46a44c23670a7af
https://doi.org/10.1158/1541-7786.22517040
https://doi.org/10.1158/1541-7786.22517040
Autor:
Su-Jae Lee, Kee-Ho Lee, Haekwon Kim, Young-Hyun Choi, Changil Kim, Sang-Gu Hwang, In-Chul Park, Soon-Young Choi, Min-Jung Kim
Supplementary Figures S1-S3 from Opposing Roles of c-Jun NH2-Terminal Kinase and p38 Mitogen-Activated Protein Kinase in the Cellular Response to Ionizing Radiation in Human Cervical Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c7dcd0d3e417527ddd7bbcae48bfbe
https://doi.org/10.1158/1541-7786.22517635.v1
https://doi.org/10.1158/1541-7786.22517635.v1
Autor:
Kee-Ho Lee, Sang Hoon Kim, Gil Hong Park, Gyesoon Yoon, Myung-Haing Cho, Su-Jae Lee, Hee-Yong Chung, Su Hwa Jang, Chang-Mo Kang, Yeun-Jin Ju, Bu-Yeo Kim, Hee Young Kim, Sun Hee Yoon, Young-Hoon Han, Miyong Yun
Supplementary Figures S1-S7 from p31comet Induces Cellular Senescence through p21 Accumulation and Mad2 Disruption
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf36381f2ec905b8925d8f56a5cfdbd4
https://doi.org/10.1158/1541-7786.22519495
https://doi.org/10.1158/1541-7786.22519495
Autor:
Jee San Lee, Jeong Eun Yoo, Haeryoung Kim, Hyungjin Rhee, Myoung Ju Koh, Ji Hae Nahm, Jin Sub Choi, Kee-Ho Lee, Young Nyun Park
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0171922 (2017)
Senescence secretome was recently reported to promote liver cancer in an obese mouse model. Steatohepatitic hepatocellular carcinoma (SH-HCC), a new variant of HCC, has been found in metabolic syndrome patients, and pericellular fibrosis, a character
Externí odkaz:
https://doaj.org/article/054c016e05cb41d5907cb426020c98fa
Autor:
Hyun-Jin Shin, Eun-Ran Park, Sun-Hee Yun, Su-Hyeon Kim, Won-Hee Jung, Seon Rang Woo, Hyun-Yoo Joo, Su Hwa Jang, Hee Yong Chung, Sung Hee Hong, Myung-Haing Cho, Joong-Jean Park, Miyong Yun, Kee-Ho Lee
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0141523 (2015)
Mad2, a key component of the spindle checkpoint, is closely associated with chromosomal instability and poor prognosis in cancer. p31comet is a Mad2-interacting protein that serves as a spindle checkpoint silencer at mitosis. In this study, we showed
Externí odkaz:
https://doaj.org/article/8fc165c4c7d14cbe818e3146e0ed25dc
Autor:
Da Woon Song, Triveni Pativada, Hong Kyu Kim, Eun Jung Lee, Woo Jung Kim, Y. H. Choi, Han Kyeom Kim, Kee Ho Lee, Myung Hwan Kim, Ku Jin Mo, Bo Yeon Seo, Seong Su Hong, Sung K. Ahn, Chun Whan Choi, Jung Hun Lee, Gil-Hong Park, Serk In Park
Publikováno v:
Journal of Medicinal Chemistry. 62:6063-6082
(E)-3,4-Dihydroxybenzylideneacetone (compound 1) inhibited receptor activator of NF-κB ligand-induced osteoclastogenesis of C57BL/6 bone marrow monocyte/macrophages with IC50 of 7.8 μM (IC50 of alendronate, 3.7 μM) while stimulating the differenti