Zobrazeno 1 - 10
of 583
pro vyhledávání: '"Keddy, P."'
Autor:
Kristen Jones, Clare Keddy, Chelsea Jenkins, Katelyn Nicholson, Ujwal Shinde, Monika A. Davare
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The ROS1 receptor tyrosine kinase (RTK) possesses the largest extracellular amino-terminal domain (ECD) among the human RTK family, yet the mechanisms regulating its activation are not fully understood. While chimeric ROS1 fusion proteins, r
Externí odkaz:
https://doaj.org/article/66839e6de01149af9218b507876cdf74
Autor:
Rajat Thawani, Matteo Repetto, Clare Keddy, Katelyn Nicholson, Kristen Jones, Kevin Nusser, Catherine Z. Beach, Guilherme Harada, Alexander Drilon, Monika A. Davare
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-11 (2024)
Abstract ROS1 tyrosine kinase inhibitors (TKIs) are highly effective in ROS1-positive non-small cell lung cancer, but resistance remains a challenge. We investigated the activity of various TKIs against wildtype and mutant ROS1, focusing on the emerg
Externí odkaz:
https://doaj.org/article/a2f0d426aed049d5ae3fab63257a9869
Autor:
Jennifer Mattock, Marie Anne Chattaway, Hassan Hartman, Timothy J. Dallman, Anthony M. Smith, Karen Keddy, Liljana Petrovska, Emma J. Manners, Sanelisiwe T. Duze, Shannon Smouse, Nomsa Tau, Ruth Timme, Dave J. Baker, Alison E. Mather, John Wain, Gemma C. Langridge
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 4, Pp 701-710 (2024)
Salmonella enterica serovar Infantis presents an ever-increasing threat to public health because of its spread throughout many countries and association with high levels of antimicrobial resistance (AMR). We analyzed whole-genome sequences of 5,284 S
Externí odkaz:
https://doaj.org/article/b0623b760f334df19d7933247425200a
Autor:
Zoe Harbottle, Amanda Nötzel, Michael A. Golding, Manvir Bhamra, Isac Kopsch, Erik Wilking, Marina Jonsson, Elissa M. Abrams, Michelle A. Halbrich, Elinor Simons, Leslie E. Roos, Jill A. Keddy-Grant, Thomas V. Gerstner, Jo-Anne St-Vincent, Sandra Ekström, Jennifer L. P. Protudjer
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 20, Iss 1, Pp 1-9 (2024)
Abstract Background While the impacts of atopic dermatitis (AD) on maternal and child sleep outcomes have been previously explored, less is known about the associations between infantile AD and sleep quality and quantity. Objective To describe the pe
Externí odkaz:
https://doaj.org/article/6348845267184d108df7631a74791d66
Autor:
Anthony Irungu Ndung'u, Joseph Mungai Keriko, Patrick Gachoki Kareru, Sammy Indire Wanakai, George Kiprono Kisoi, Grace Gakii Keddy
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e29012- (2024)
Rodents have remained a menace to humans, hence there is need to evaluate for anti-rodent activity of cheap and environment friendly control methods. This study aimed at evaluating the anti-rodenticidal activity of Thevetia (T.) peruviana fruit metha
Externí odkaz:
https://doaj.org/article/181cfa95162240b38bf4edacd08ded7a
Autor:
Ayel Luis R. Batac, Kaitlyn A. Merrill, Michael A. Golding, Manvir Bhamra, Zoe Harbottle, Isac Kopsch, Erik Wilking, Marina Jonsson, Sandra Ekström, Elissa M. Abrams, Michelle A. Halbrich, Elinor Simons, Leslie E. Roos, Jill A. Keddy-Grant, Thomas V. Gerstner, Jo-Anne St-Vincent, Jennifer L. P. Protudjer
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 19, Iss 1, Pp 1-9 (2023)
Abstract Background Childhood atopic dermatitis can have a negative effect on caregivers’ quality of life and stress levels due to the burdensome nature of its treatment. Given that the condition often emerges in infancy, atopic dermatitis-related
Externí odkaz:
https://doaj.org/article/0a8109b10eb5420da085abdbff19c821
Autor:
George E. Stenhouse, Karen H. Keddy, Rebecca J. Bengtsson, Neil Hall, Anthony M. Smith, Juno Thomas, Miren Iturriza-Gómara, Kate S. Baker
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Shigellosis, a leading cause of diarrhoeal mortality and morbidity globally, predominantly affects children under five years of age living in low- and middle-income countries. While whole genome sequence analysis (WGSA) has been effectively
Externí odkaz:
https://doaj.org/article/8a1c9927a4c8493ba55330c04e7144f1
Autor:
Libby Obumneke Onyeka, Abiodun A. Adesiyun, Arshad Ismail, Mushal Allam, Karen H. Keddy, Peter N. Thompson
Publikováno v:
Pathogens, Vol 13, Iss 9, p 732 (2024)
We used whole genome sequencing (WGS) as an epidemiologic surveillance tool to elucidate the transmission dynamics of Shiga toxin-producing Escherichia coli (STEC) strains along the beef production chain in South Africa. Isolates were obtained from a
Externí odkaz:
https://doaj.org/article/13764de1cd81405c942391b60fc7ddae
Autor:
Rajat Thawani, Matteo Repetto, Clare Keddy, Katelyn Nicholson, Kristen Jones, Kevin Nusser, Catherine Z. Beach, Guilherme Harada, Alexander Drilon, Monika A. Davare
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/31196ad66dfb436eb7493219d57ee85d
The importance of estimating the burden of disease from foodborne transmission of Trypanosoma cruzi.
Autor:
Lucy J Robertson, Arie H Havelaar, Karen H Keddy, Brecht Devleesschauwer, Banchob Sripa, Paul R Torgerson
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 2, p e0011898 (2024)
Chagas disease (ChD), caused by infection with the flagellated protozoan, Trypanosoma cruzi, has a complicated transmission cycle with many infection routes. These include vector-borne (via the triatomine (reduviid bug) vector defecating into a skin
Externí odkaz:
https://doaj.org/article/d9320ab28bdf4d4f942461e0173029c5