Decoding the centromeric nucleosome through CENP-N

Autor: Satyakrishna Pentakota, Keda Zhou, Charlotte Smith, Stefano Maffini, Arsen Petrovic, Garry P Morgan, John R Weir, Ingrid R Vetter, Andrea Musacchio, Karolin Luger

Publikováno v: eLife, Vol 6 (2017)

Centromere protein (CENP) A, a histone H3 variant, is a key epigenetic determinant of chromosome domains known as centromeres. Centromeres nucleate kinetochores, multi-subunit complexes that capture spindle microtubules to promote chromosome segregat

Externí odkaz: https://doaj.org/article/c10118af6b92425bb5254d424be03270

The m

Autor: Hengyou, Weng, Feng, Huang, Zhaojin, Yu, Zhenhua, Chen, Emily, Prince, Yalin, Kang, Keren, Zhou, Wei, Li, Jiacheng, Hu, Chen, Fu, Tursunjan, Aziz, Hongzhi, Li, Jingwen, Li, Ying, Yang, Li, Han, Subo, Zhang, Yuelong, Ma, Mingli, Sun, Huizhe, Wu, Zheng, Zhang, Mark, Wunderlich, Sean, Robinson, Daniel, Braas, Johanna Ten, Hoeve, Bin, Zhang, Guido, Marcucci, James C, Mulloy, Keda, Zhou, Hong-Fang, Tao, Xiaolan, Deng, David, Horne, Minjie, Wei, Huilin, Huang, Jianjun, Chen

Publikováno v: Cancer cell. 40(12)

N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a47b001c9922586b27780559c51dd9e1
https://pubmed.ncbi.nlm.nih.gov/36306790

The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia

Autor: Hengyou Weng, Feng Huang, Zhaojin Yu, Zhenhua Chen, Emily Prince, Yalin Kang, Keren Zhou, Wei Li, Jiacheng Hu, Chen Fu, Tursunjan Aziz, Hongzhi Li, Jingwen Li, Ying Yang, Li Han, Subo Zhang, Yuelong Ma, Mingli Sun, Huizhe Wu, Zheng Zhang, Mark Wunderlich, Sean Robinson, Daniel Braas, Johanna ten Hoeve, Bin Zhang, Guido Marcucci, James C. Mulloy, Keda Zhou, Hong-Fang Tao, Xiaolan Deng, David Horne, Minjie Wei, Huilin Huang, Jianjun Chen

Publikováno v: Cancer Cell. 40:1566-1582.e10

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a43da9b2f84dfd4014b3b6cf991ae236
https://doi.org/10.1016/j.ccell.2022.10.004

Virus-encoded histone doublets are essential and form nucleosome-like structures

Autor: Chelsea Marie Toner, Karolin Luger, Yang Liu, Keda Zhou, Hugo Bisio, Chantal Abergel, Sandra Jeudy, Nadège Philippe, Samuel Bowerman, Garrett B. Edwards, Alison E. White

Publikováno v: Cell
Cell, Elsevier, 2021, 184, pp.4237-4250.e19. ⟨10.1016/j.cell.2021.06.032⟩
Cell, 2021, 184, pp.4237-4250.e19. ⟨10.1016/j.cell.2021.06.032⟩
CellPress

International audience; The organization of genomic DNA into defined nucleosomes has long been viewed as a hallmark of eukaryotes. This paradigm has been challenged by the identification of “minimalist” histones in archaea and more recently by th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa2a625fbd3641d57a44078fe90bbbb
https://hal-amu.archives-ouvertes.fr/hal-03329028/file/1-s2.0-S0092867421008230-main.pdf

FACT caught in the act of manipulating the nucleosome

Autor: Yong Zi Tan, Sheena D'Arcy, Hui Wei, Karolin Luger, Naifu Zhang, Clinton S. Potter, Zhening Zhang, Keda Zhou, Bridget Carragher, Yang Liu

Publikováno v: Nature

The organization of genomic DNA into nucleosomes profoundly affects all DNA-related processes in eukaryotes. The histone chaperone known as ‘facilitates chromatin transcription’ (FACT1) (consisting of subunits SPT16 and SSRP1) promotes both disas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed7620ec7a79c0316f121a62c39ec538
https://doi.org/10.1038/s41586-019-1820-0