Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Kecheng Lei"'
Autor:
Marybeth G. Yonk, Megan A. Lim, Charee M. Thompson, Muhibullah S. Tora, Yuliya Lakhina, Yuhong Du, Kimberly B. Hoang, Annette M. Molinaro, Nicholas M. Boulis, Wael Hassaneen, Kecheng Lei
Publikováno v:
Pharmacological Research, Vol 208, Iss , Pp 107390- (2024)
Glioma is one of the most common central nervous system (CNS) cancers that can be found within the brain and the spinal cord. One of the pressing issues plaguing the development of therapeutics for glioma originates from the selective and semipermeab
Externí odkaz:
https://doaj.org/article/6359ac68565e4003b6945b3c56b390fe
Autor:
Muhibullah S. Tora, Stewart G. Neill, Yuliya Lakhina, Hemza Assed, Michelle Zhang, Purva P. Nagarajan, Thais Federici, Juanmarco Gutierrez, Kimberly B. Hoang, Yuhong Du, Kecheng Lei, Nicholas M. Boulis
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background Spinal cord glioma (SCG) is considered an orphan disease that lacks effective treatment options with margins that are surgically inaccessible and an overall paucity of literature on the topic. The tumor microenvironment is a criti
Externí odkaz:
https://doaj.org/article/32602bf37c574cc6a654e0f3b3fc2421
Autor:
Kecheng Lei, Xiaoxia Gu, Alvaro G. Alvarado, Yuhong Du, Shilin Luo, Eun Hee Ahn, Seong Su Kang, Bing Ji, Xia Liu, Hui Mao, Haian Fu, Harley I. Kornblum, Lingjing Jin, Hua Li, Keqiang Ye
Publikováno v:
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-21 (2020)
Abstract Background Glioblastoma (GBM) is a universally lethal tumor with frequently overexpressed or mutated epidermal growth factor receptor (EGFR). NADPH quinone oxidoreductase 1 (NQO1) and glutathione-S-transferase Pi 1 (GSTP1) are commonly upreg
Externí odkaz:
https://doaj.org/article/25ab2eba2ce34f0bb9e12d46df9f8c43
Publikováno v:
Redox Biology, Vol 34, Iss , Pp 101578- (2020)
Glioblastoma (GBM) is the most common and most aggressive brain tumor, associated with high levels of reactive oxidative species (ROS) due to metabolic and signaling aberrations. High ROS levels are detrimental to cells, but it remains incompletely u
Externí odkaz:
https://doaj.org/article/5cc1073712d24582b57657d92fee8b3e
Autor:
Keqiang Ye, Lingjing Jin, Laura E. Edgington-Mitchell, Hua Li, Xia Liu, Jianming Liao, Chun Chen, Eun Hee Ahn, Seong Su Kang, Kecheng Lei
Supplementary figs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3afb1827660b59eb4ec7271a3c07c25f
https://doi.org/10.1158/1535-7163.22522434
https://doi.org/10.1158/1535-7163.22522434
Autor:
Keqiang Ye, Lingjing Jin, Laura E. Edgington-Mitchell, Hua Li, Xia Liu, Jianming Liao, Chun Chen, Eun Hee Ahn, Seong Su Kang, Kecheng Lei
Solid tumors start as a local disease, but some are capable of metastasizing to the lymph nodes and distant organs. The hypoxic microenvironment, which is critical during cancer development, plays a key role in regulating cancer progression and metas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb07f39af998807989c5a1b00d3bc49
https://doi.org/10.1158/1535-7163.c.6543378.v1
https://doi.org/10.1158/1535-7163.c.6543378.v1
203 Novel Adeno-Associated Viral (AAV) Vectors for Preferential Targeting of Peripheral Nerve Tumors
Autor:
Alexander Craig McConnell Greven, Kecheng Lei, Purva Nagarajan, Ana Carneiro, David Schafer, Nicholas M. Boulis
Publikováno v:
Neurosurgery. 69:34-35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ce753550f82974ea761d7930844b995
https://doi.org/10.1227/neu.0000000000002375_203
https://doi.org/10.1227/neu.0000000000002375_203
Autor:
Hui Mao, Lingjing Jin, Yuhong Du, Eun Hee Ahn, Xia Liu, Seong Su Kang, Keqiang Ye, Kecheng Lei, Hua Li, Alvaro G. Alvarado, Shilin Luo, Harley I. Kornblum, Xiaoxia Gu, Haian Fu, Bing Ji
Publikováno v:
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-21 (2020)
Journal of Hematology & Oncology
Journal of Hematology & Oncology
Background Glioblastoma (GBM) is a universally lethal tumor with frequently overexpressed or mutated epidermal growth factor receptor (EGFR). NADPH quinone oxidoreductase 1 (NQO1) and glutathione-S-transferase Pi 1 (GSTP1) are commonly upregulated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07832eec88fac04a61a75213b705e218
http://link.springer.com/article/10.1186/s13045-020-00979-y
http://link.springer.com/article/10.1186/s13045-020-00979-y
Autor:
Yijue Shen, Yichun Xu, Weifang Tong, Liwen Zhang, Kecheng Lei, Jingxing Zhang, Yijing He, Lingjing Jin
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)
Parkinson’s disease (PD) is a neurodegenerative disease characterized by the gradual loss of dopaminergic (DA) neurons in the substantia nigra (SN) and the formation of intracellular Lewy bodies (LB) in the brain, which aggregates α-synuclein (α-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39600ddf1c19ac314c5743997a2316a0
https://doi.org/10.1155/2020/8951907
https://doi.org/10.1155/2020/8951907
Autor:
Muhibullah S Tora, Kecheng Lei, Purva P Nagarajan, David P Bray, Rima S Rindler, Stewart G Neill, Michelle Zhang, Pavlos Texakalidis, Andrey Krasnopeyev, Crystal Gergye, Raphael James, John N Oshinski, Thais Federici, Jeffrey N Bruce, Peter Canoll, Nicholas M Boulis
Publikováno v:
Neuro-Oncology. 24:vii297-vii297
BACKGROUND The current literature does not describe a reproducible large animal model of intracranial high-grade glioma (HGG). Prior work has demonstrated the feasibility of inducing HGG de-novo in rodents by targeting specific oncogenic pathways. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a680c9689e9f1f1fd981fa6372817f2a
https://doi.org/10.1093/neuonc/noac209.1155
https://doi.org/10.1093/neuonc/noac209.1155