Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Keaton M Crosse"'
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190597 (2018)
The cellular localisation of many innate signalling events following viral infection has yet to be elucidated, however there has been a few cases in which membranes of certain cellular organelles have acted as platforms to these events. Of these, lip
Externí odkaz:
https://doaj.org/article/160909c0edf6405f8ff9e9b5ce345a73
Autor:
Rachel A. Prescott, Alec P. Pankow, Maren de Vries, Keaton M. Crosse, Roosheel S. Patel, Mark Alu, Cynthia Loomis, Victor Torres, Sergei Koralov, Ellie Ivanova, Meike Dittmann, Brad R. Rosenberg
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-17 (2023)
Abstract Background The airway epithelium is composed of diverse cell types with specialized functions that mediate homeostasis and protect against respiratory pathogens. Human airway epithelial (HAE) cultures at air–liquid interface are a physiolo
Externí odkaz:
https://doaj.org/article/373f7a744e00421f9130874a55811427
Autor:
Bruno A. Rodriguez-Rodriguez, Grace O. Ciabattoni, Ralf Duerr, Ana M. Valero-Jimenez, Stephen T. Yeung, Keaton M. Crosse, Austin R. Schinlever, Lucie Bernard-Raichon, Joaquin Rodriguez Galvan, Marisa E. McGrath, Sanjay Vashee, Yong Xue, Cynthia A. Loomis, Kamal M. Khanna, Ken Cadwell, Ludovic Desvignes, Matthew B. Frieman, Mila B. Ortigoza, Meike Dittmann
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Small animal models have been a challenge for the study of SARS-CoV-2 transmission, with most investigators using golden hamsters or ferrets. Mice have the advantages of low cost, wide availability, less regulatory and husbandry challenges,
Externí odkaz:
https://doaj.org/article/4f82157bf5264550bc33dcd07d963594
Publikováno v:
Microorganisms, Vol 9, Iss 7, p 1389 (2021)
SARS-CoV-2 and HIV are zoonotic viruses that rapidly reached pandemic scale, causing global losses and fear. The COVID-19 and AIDS pandemics ignited massive efforts worldwide to develop antiviral strategies and characterize viral architectures, biolo
Externí odkaz:
https://doaj.org/article/550044eb0ece4cb4b8abb68372aa6f7c
Autor:
Joaquin Rodriguez Galvan, Maren de Vries, Ashley Fisher, Rachel A Prescott, Keaton M Crosse, Ralf Duerr, Meike Dittmann
Publikováno v:
bioRxiv
Proteases play key roles in viral replication cycles. They can provide cleavage maturation of viral glycoproteins, processing of viral polyproteins, or disassembly of viral capsids. Thus, proteases constitute ideal targets for antiviral intervention
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0dd79178f5f68afc0c6673c26748b07
https://europepmc.org/articles/PMC9681043/
https://europepmc.org/articles/PMC9681043/
Autor:
Bruno A. Rodriguez-Rodriguez, Grace O. Ciabattoni, Ralf Duerr, Ana M Valero-Jimenez, Stephen T. Yeung, Keaton M. Crosse, Austin R. Schinlever, Lucie Bernard-Raichon, Joaquin J. Rodriguez-Galvan, Marisa E. McGrath, Sanjay Vashee, Yong Xue, Cynthia Loomis, Kamal M. Khanna, Kenneth Cadwell, Ludovic Desvignes, Matthew F. Frieman, Mila B Ortigoza, Meike Dittmann
Publikováno v:
bioRxiv
Small animal models have been a challenge for the study of SARS-CoV-2 transmission, with most investigators using golden hamsters or ferrets1, 2. Mice have the advantages of low cost, wide availability, less regulatory and husbandry challenges, and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9447e8bb6eafe0996229b35e9df89702
https://europepmc.org/articles/PMC9558433/
https://europepmc.org/articles/PMC9558433/
Autor:
Karla J. Helbig, Donna R. Whelan, Jillian M. Carr, Ross D O'Shea, Linda M. Wakim, Keaton M. Crosse, Weisan Chen, Mubing Duan, Ebony A. Monson
Publikováno v:
Nature Communications
Cell Stress
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Cell Stress
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Lipid droplets (LDs) are increasingly recognized as critical organelles in signalling events, transient protein sequestration and inter-organelle interactions. However, the role LDs play in antiviral innate immune pathways remains unknown. Here we de
Autor:
Ebony A. Monson, Keaton M. Crosse, Elizabeth Ngoc Hoa Tran, Renato Morona, Monique Smith, Michael R. Beard, Min Yan Teh, Alistair J. Standish, Karla J. Helbig
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
The role of interferon and interferon stimulated genes (ISG) in limiting bacterial infection is controversial, and the role of individual ISGs in the control of the bacterial life-cycle is limited. Viperin, is a broad acting anti-viral ISGs, which re
Publikováno v:
Microorganisms
Microorganisms, Vol 9, Iss 1389, p 1389 (2021)
Microorganisms, Vol 9, Iss 1389, p 1389 (2021)
SARS-CoV-2 and HIV are zoonotic viruses that rapidly reached pandemic scale causing global losses and fear. The COVID-19 and AIDS pandemics ignited massive efforts worldwide to develop antiviral strategies and characterize viral architectures, biolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0867a9d0a92cd328be2c18ada68590eb
Autor:
Subir Saker, Yeu-Yang Tseng, Keaton M. Crosse, Ebony A. Monson, E. Neil G. Marsh, Michael R. Beard, Monique Smith, Kylie H. Van der Hoek, David C. Tscharke, Peter Revill, Karla J. Helbig, Arti B. Dumbrepatil
Publikováno v:
Immunology and cell biologyReferences. 99(4)
Viperin is an interferon-inducible protein that is pivotal for eliciting an effective immune response against an array of diverse viral pathogens. Here we describe a mechanism of viperin's broad antiviral activity by demonstrating the protein's abili