Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Keat H. Teoh"'
Autor:
Kirsten R. Benjamin, D. Dengrove, T. Treynor, Hanxiao Jiang, Darwin W. Reed, Karl Fisher, Douglas J. Pitera, S. Secrest, Kenneth W. Ellens, Patrick J. Westfall, M. Yu, Rika Regentin, T. Iqbal, A. Main, H. Tsuruta, Derek McPhee, Tizita Horning, R. Vazquez, S. Bajad, Ronald Henry, G. Dang, Keat H. Teoh, Jefferson C. Lievense, J. Galazzo, Scott Fickes, L. Kizer, Don Diola, Anna Tai, K. K. Reiling, B. Lieu, Patrick S. Covello, Lars F. Westblade, G. Dorin, Sara P. Gaucher, M. Fleck, Jacob R. Lenihan, M. Hepp, Michael D. Leavell, N. S. Renninger, Lishan Zhao, D. Melis, Diana Eng, Lan Xu, Jay D. Keasling, Christopher J. Paddon, Nathan A. Moss, T. Geistlinger, Jack D. Newman, Devin R Polichuk, Yansheng Zhang
Publikováno v:
Nature. 496:528-532
Saccharomyces cerevisiae is engineered to produce high concentrations of artemisinic acid, a precursor of the artemisinin used in combination therapies for malaria treatment; an efficient and practical chemical process to convert artemisinic acid to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b3b963d2eb566628f4ca5c84b8ca8a
https://doi.org/10.1038/nature12051
https://doi.org/10.1038/nature12051
Publikováno v:
Phytochemistry. 68:1864-1871
Artemisinin, a sesquiterpene lactone endoperoxide derived from the glandular secretory trichomes (GSTs) of Artemisia annua, provides the basis for the most effective treatments of malaria. The biology and biochemistry of GSTs of the Asteraceae and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4ffba0eead3ef67050585d7718be368
https://doi.org/10.1016/j.phytochem.2007.02.016
https://doi.org/10.1016/j.phytochem.2007.02.016
Autor:
Ganapathy Sivakumar, Keat H. Teoh
Microalgae can be used as renewable biofactories for valuable fatty acids and triacylglycerols. The new alga Stichococcus bacillaris strain siva2011 produces significant level of lipids that can be used in pharmaceutical or fuel industries. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42a16c3013fb953a71197ad0f6f385c5
https://doi.org/10.1016/b978-0-12-800776-1.00028-5
https://doi.org/10.1016/b978-0-12-800776-1.00028-5
Autor:
Cynthia Alcántara, Sarmidi Amin, Cristiano V.M. Araújo, Ali Bahadar, Lieselot Balduyck, Bernardo Bañuelos-Hernández, Luísa Barreira, Josué I. Beltrán-López, Michael J. Betenbaugh, Arghya Bhattacharya, Eleftherios Bonos, Charlotte Bruneel, Laura Bulgariu, Faizal Bux, Poonam Choudhary, Efterpi Christaki, Samuel Cirés, Luísa Custódio, Cecilia Faraloni, Panagiota Florou-Paneri, Imogen Foubert, Katkam N. Gangadhar, Maria Gavrilescu, Koen Goiris, A. Catarina Guedes, Benoit Guieysse, Abhishek Guldhe, Sanjay Kumar Gupta, Bernardo J. Guzman, Kirsten Heimann, S.W.A. Himaya, Seong-Joo Hong, Roger Huerlimann, Pavan P. Jutur, Kyong-Hwa Kang, Prachi Kaushik, M. Bilal Khan, M.A. Asim K. Jalwana, Se-Kwon Kim, Ayse Kose, Man Kee Lam, Choul-Gyun Lee, Keat Teong Lee, Yuan Kun Lee, Baboucarr Lowe, F. Xavier Malcata, Anushree Malik, Panchanathan Manivasagan, Ignacio Moreno-Garrido, Raúl Muñoz, Koenraad Muylaert, Asha A. Nesamma, Daphne H.P. Ng, Yi Kai Ng, Dai-Hung Ngo, Victor H. Oh, Jorge Olmos Soto, Suphi S. Oncel, George A. Oyler, J. Paniagua-Michel, Hugo Pereira, José C.M. Pires, Esther Posadas, Kurniadhi Prabandono, Sanjeev K. Prajapati, P.T. Pratheesh, Zhong-Ji Qian, Ismail Rawat, Sergio Rosales-Mendoza, Julian N. Rosenberg, BoMi Ryu, Rakesh Chandra Saxena, Kashif M. Shaikh, Hui Shen, Jasvinder Singh, Poonam Singh, Ganapathy Sivakumar, Isabel Sousa-Pinto, Leanne Sparrow, Keat H. Teoh, Giuseppe Torzillo, Fazilet Vardar, João Varela, Jayachandran Venkatesan, M. Vineetha, Thanh-Sang Vo, Geng Yu, Luc De Cooman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6b201a3f8f46a6be7c49dbf29548c11
https://doi.org/10.1016/b978-0-12-800776-1.01002-5
https://doi.org/10.1016/b978-0-12-800776-1.01002-5
Publikováno v:
FEBS Letters. 580:1411-1416
Artemisinin, a sesquiterpene lactone endoperoxide derived from the plant Artemisia annua, forms the basis of the most important treatments of malaria in use today. In an effort to elucidate the biosynthesis of artemisinin, an expressed sequence tag a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d75d816b4459134a4a1816b1aef532
https://doi.org/10.1016/j.febslet.2006.01.065
https://doi.org/10.1016/j.febslet.2006.01.065
Autor:
Darwin W. Reed, Patrick S. Covello, Keat H. Teoh, Patrick R. Arsenault, Anthony McMickle, Pamela J. Weathers
Artemisia annua L. produces the sesquiterpene lactone, artemisinin, a potent antimalarial drug that is also effective in treating other parasitic diseases, some viral infections and various neoplasms. Artemisinin is also an allelopathic herbicide tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2361264cad5545ada765d8a97f2d2db5
https://europepmc.org/articles/PMC3106422/
https://europepmc.org/articles/PMC3106422/
Autor:
Keat H. Teoh, Douglas J. H. Olson, Andrew R. S. Ross, Yansheng Zhang, Alain Goossens, Patrick S. Covello, Lies Maes, Darwin W. Reed
Publikováno v:
The Journal of biological chemistry. 283(31)
At some point during biosynthesis of the antimalarial artemisinin in glandular trichomes of Artemisia annua, the Delta11(13) double bond originating in amorpha-4,11-diene is reduced. This is thought to occur in artemisinic aldehyde, but other interme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f357c3c445b2005882a5ab1b43c883
https://pubmed.ncbi.nlm.nih.gov/18495659
https://pubmed.ncbi.nlm.nih.gov/18495659