Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Keary Engle"'
Autor:
Hui-Qi Ni, Jing-Cheng Dai, Shouliang Yang, Richard Loach, Matthew Chuba, Indrawan McAlpine, Keary Engle
We describe a catalytic cascade sequence involving directed C(sp3)–H activation followed by β-heteroatom elimination to generate a PdII(π-alkene) intermediate that then undergoes redox-neutral annulation with an ambiphilic aryl halide to access 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b95d9b5d6198510f77071ff0c794251b
https://doi.org/10.26434/chemrxiv-2023-qv5bh
https://doi.org/10.26434/chemrxiv-2023-qv5bh
Autor:
Camille Rubel, Yilin Cao, Tamara El-Hayek Ewing, Gabriele Laudadio, Gregory Beutner, Steven Wisniewski, Xiangyu Wu, Phil Baran, Julien Vantourout, Keary Engle
Over the last fifty years, the use of nickel catalysts for facilitating organic transformations has skyrocketed. Ni(0) sources act as useful precatalysts because they can enter a catalytic cycle through ligand exchange, without needing to undergo add
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4d5c82ac6948dfc97be5fcd0b8667da
https://doi.org/10.26434/chemrxiv-2023-sgnl1
https://doi.org/10.26434/chemrxiv-2023-sgnl1
Autor:
Hui-Qi Ni, Warabhorn Rodphon, Nicholas Scherschel, Shouliang Yang, Fen Wang, Indrawan McAlpine, Davin Piercey, Keary Engle
A facile approach to densely functionalized cyclopropanes is described. The reaction proceeds under mild conditions via the directed nucleopalladation of non-conjugated alkenes with readily available pronucleophiles and gives excellent yields and goo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::632453f7c6182866ff5dbaa92c271ad5
https://doi.org/10.26434/chemrxiv-2023-b1bdb
https://doi.org/10.26434/chemrxiv-2023-b1bdb
A positionally selective alkene isomerization in which modulation of the ligand environment of the homogeneous tungsten catalyst grants access to either the (E)- or (Z)-stereoisomer is described. Compared to previously reported alkene isomerization m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4afcf310e0fe0496f22ccf612734693c
https://doi.org/10.26434/chemrxiv-2023-hdj6t
https://doi.org/10.26434/chemrxiv-2023-hdj6t
Because internal alkenes are more challenging synthetic targets than terminal alkenes, metal-catalyzed olefin trans-position (i.e., positional isomerization) approaches have emerged to afford valuable E- or Z- internal alkenes from their complementar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::478f7688a7b26e21c76481f7f8130abd
https://doi.org/10.26434/chemrxiv-2022-x8ssk
https://doi.org/10.26434/chemrxiv-2022-x8ssk
Autor:
Omar Apolinar, Taeho Kang, Turki Alturaifi, Pranali Bedekar, Camille Rubel, Joseph Derosa, Brittany Sanchez, Quynh Wong, Emily Sturgell, Jason Chen, Steven Wisniewski, Peng Liu, Keary Engle
An asymmetric 1,2-dicarbofunctionalization of unactivated alkenes with aryl iodides and aryl/alkenylboronic esters under nickel/bioxazoline catalysis is disclosed. A wide array of aryl and alkenyl nucleophiles are tolerated, furnishing the products i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8573342fefaa0d2daf2d14c93aeb1b96
https://doi.org/10.26434/chemrxiv-2022-lvtjq
https://doi.org/10.26434/chemrxiv-2022-lvtjq
The catalytic enantioselective synthesis of α-chiral alkenes and alkynes represents a powerful strategy for rapid generation of molecular complexity. Herein, we report a transient directing group facilitated site-selective palladium-catalyzed reduct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::619234ffcbcd9586e8f4380b8198860b
https://doi.org/10.26434/chemrxiv-2022-h8w0k
https://doi.org/10.26434/chemrxiv-2022-h8w0k
The site-selective palladium-catalyzed three-component coupling of unactivated alkenyl carbonyl compounds, aryl- or alkenylboronic acids, and N-fluorobenzenesulfonimide is described herein. Tuning of the steric environment on the bidentate directing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbb59d7303088b4fffbd7faa8eb3c14b
https://doi.org/10.26434/chemrxiv-2022-t2zb4
https://doi.org/10.26434/chemrxiv-2022-t2zb4
Palladium(II)-catalyzed C(alkenyl)–H alkenylation enabled by a transient directing group (TDG) strategy is described. The dual catalytic process takes advantage of reversible condensation between an alkenyl aldehyde substrate and an amino acid TDG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a200dd4e55bbb8066089ad62aba0a629
https://doi.org/10.26434/chemrxiv-2022-d0zfn
https://doi.org/10.26434/chemrxiv-2022-d0zfn
Autor:
Van Tran, Nana Kim, Camille Rubel, Xiangyu Wu, Taeho Kang, Tanner Jankins, Zi-Qi Li, Matthew Joannou, Sloan Ayers, Milan Gembicky, Jake Bailey, Emily Sturgell, Brittany Sanchez, Jason Chen, Song Lin, Martin Eastgate, Steven Wisniewski, Keary Engle
A flurry of recent research has centered on harnessing the power of nickel catalysis in organic synthesis. These efforts have been bolstered by contemporaneous synthesis, characterization, and optimization of well-defined nickel (pre)catalysts with d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f4f8da20fe598dac98650fc88fd83fc
https://doi.org/10.26434/chemrxiv-2022-7zjvh
https://doi.org/10.26434/chemrxiv-2022-7zjvh