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pro vyhledávání: '"Kearsley M. Dillon"'
Autor:
Manuela Pose, Kearsley M. Dillon, Ana Denicola, Beatriz Alvarez, John B. Matson, Matías N. Möller, Ernesto Cuevasanta
Hydrogen sulfide (H2S) is produced endogenously by several enzymatic pathways and modulates physiological functions in mammals. Quantification of H2S in biochemical systems re-mains challenging because of the presence of interferents with similar rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d04312daad9790a75de5aad831d9eed7
https://hdl.handle.net/10919/114931
https://hdl.handle.net/10919/114931
Autor:
Kearsley M. Dillon, John B. Matson
Publikováno v:
ACS Chem Biol
Hydrogen sulfide (H(2)S) has gained significant attention as a potent bioregulator in the redox metabolome, but it is just one of many reactive sulfur species (RSS). Recently, small molecule persulfides (structure RSSH) have emerged as an RSS of part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::529a34702e02f05f2f79583e30ee3cb3
https://europepmc.org/articles/PMC9494198/
https://europepmc.org/articles/PMC9494198/
Publikováno v:
Synlett. 30:525-531
H2S, persulfides (R–SSH), and related sulfur species have recently received attention due to the pronounced physiological effects they elicit. Delivering sulfur signaling molecules in a controlled manner presents many challenges, as many available
Publikováno v:
Angew Chem Int Ed Engl
Overproduction of superoxide anion (O(2)∙(−)), the primary cellular reactive oxygen species (ROS), is implicated in various human diseases. To reduce cellular oxidative stress caused by overproduction of superoxide, we developed a compound that r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8ccbdc6ca2548259ada0974326677fd
https://europepmc.org/articles/PMC7719095/
https://europepmc.org/articles/PMC7719095/
Publikováno v:
ACS Macro Lett
Related biologically to the known gasotransmitter hydrogen sulfide (H(2)S), persulfides (R–SSH) have recently been recognized as native signaling compounds and redox regulators in their own right. Reported here is the synthesis, characterization, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32993353e82e9191eece27d2c5a04396
https://europepmc.org/articles/PMC7665160/
https://europepmc.org/articles/PMC7665160/
Publikováno v:
Angewandte Chemie International Edition. 57:6324-6328
Persulfides (R–SSH) have been hypothesized as critical components in sulfur-mediated redox cycles and as potential signaling compounds, similar to hydrogen sulfide (H(2)S). Hindering the study of persulfides is a lack of persulfide donor compounds
Publikováno v:
Biochemical Pharmacology. 149:110-123
Hydrogen sulfide (H2S) is a ubiquitous small gaseous signaling molecule, playing an important role in many physiological processes and joining nitric oxide and carbon monoxide in the group of signaling agents termed gasotransmitters. Endogenous conce
Autor:
Chadwick R. Powell, John B. Matson, Mingjun Zhou, Kuljeet Kaur, Kearsley M. Dillon, Mohammed Alaboalirat
Publikováno v:
ACS Chem Biol
We report a synthetic route toward a family of functional COS/H(2)S-releasing N-substituted N-thiocarboxyanhydrides (NTAs) with functionalities to accommodate popular conjugation reactions, including olefin cross metathesis, thiol-ene, and copper-cat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171e1ba86264bedc1acff6f56ef39445
https://europepmc.org/articles/PMC6911359/
https://europepmc.org/articles/PMC6911359/
Publikováno v:
Biochem Pharmacol
Nitric oxide (NO) and hydrogen sulfide (H(2)S) are industrial toxins or pollutants; however, both are produced endogenously and have important biological roles in most mammalian tissues. The recognition that these gasotransmitters have a role in phys
Publikováno v:
Biochemical pharmacology. 149
Hydrogen sulfide (H(2)S) is a ubiquitous small gaseous signaling molecule, playing an important role in many physiological processes and joining nitric oxide and carbon monoxide in the group of signaling agents termed gasotransmitters. Endogenous con