Výsledky vyhledávání - "Kearney, Sinéad M."

Label-free multi parameter optical interrogation of endothelial activation in single cells using a lab on a disc platform

Autor: King, Damien, Glynn, Macdara, Cindrić, Sandra, O'Connell, Tríona M., Hakimjavadi, Roya, Kearney, Sinéad M., Ackermann, Tobias, Munoz-Berbel, Xavier, Llobera, Andreu, Simonsen, Ulf, Laursen, Britt E., Redmond, Eileen M., Cahill, Paul A., Ducrée, Jens

Publikováno v: King, Damien, Glynn, Macdara ORCID: 0000-0002-6347-4348 , Cindrić, Sandra ORCID: 0000-0002-8303-100X , O'Connell, Tríona M., Hakimjavadi, Roya, Kearney, Sinéad M., Ackermann, Tobias, Munoz-Berbel, Xavier ORCID: 0000-0002-6447-5756 , Llobera, Andreu ORCID: 0000-0002-2941-478X , Simonsen, Ulf ORCID: 0000-0002-2169-7666 , Laursen, Britt E. ORCID: 0000-0001-5059-962X , Redmond, Eileen M. ORCID: 0000-0001-8642-4418 , Cahill, Paul A. ORCID: 0000-0002-5385-6502 and Ducrée, Jens ORCID: 0000-0002-0366-1897 (2019) Label-free multi parameter optical interrogation of endothelial activation in single cells using a lab on a disc platform. Scientific Reports, 9 . ISSN 2045-2322

Cellular activation and inflammation leading to endothelial dysfunction is associated with cardiovascular disease (CVD). We investigated whether a single cell label-free multi parameter optical interrogation system can detect endothelial cell and end

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______119::2933c0d3594c4486a4f9759bb83b713f
http://doras.dcu.ie/27460/

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Akademický článek

Density-Gradient Mediated Band Extraction of Leukocytes from Whole Blood Using Centrifugo-Pneumatic Siphon Valving on Centrifugal Microfluidic Discs.

Autor: Kinahan, David J.^1,2 david.kinahan@dcu.ie, Kearney, Sinéad M.^1,2, Kilcawley, Niamh A.^1,2, Early, Philip L.^1,2, Glynn, Macdara T.^1,2, Ducrée, Jens^1,2 jens.ducree@dcu.ie

Publikováno v: PLoS ONE. 5/11/2016, Vol. 11 Issue 5, p1-13. 13p.

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Laboratory unit operations on centrifugal lab-on-a-disc cartridges using dissolvable-film enabled flow control

Autor: Kinahan, David J., Glynn, Macdara, Kilcawley, Niamh, Kearney, Sinéad M., Ducrée, Jens

Publikováno v: Kinahan, David J. ORCID: 0000-0003-1968-2016 , Glynn, Macdara ORCID: 0000-0002-6347-4348 , Kilcawley, Niamh, Kearney, Sinéad M. and Ducrée, Jens ORCID: 0000-0002-0366-1897 (2014) Laboratory unit operations on centrifugal lab-on-a-disc cartridges using dissolvable-film enabled flow control. In: 4th European Conference on Microfluidics, 10-12 Dec 2014, Limerick, Ireland.

The suitability of the centrifugal “lab-on-a-disc” (LoaD) platform for point-of-use / point-of-care deployment, where ruggedness, portability, rapid turn-around times and ease-of-use are key, has resulted in increased interest from the academic c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______119::c57d8c94a9c4d309fe714baeb42426e0
http://doras.dcu.ie/20340/

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Paper imbibition for timing of multi-step liquid handling protocols on event-triggered centrifugal microfluidic lab-on-a-disc platforms

Autor: Kinahan, David J., Kearney, Sinéad M., Faneuil, Oliver, Glynn, Macdara, Dimov, Nikolay, Ducrée, Jens

Publikováno v: Kinahan, David J. ORCID: 0000-0003-1968-2016 , Kearney, Sinéad M., Faneuil, Oliver, Glynn, Macdara ORCID: 0000-0002-6347-4348 , Dimov, Nikolay and Ducrée, Jens ORCID: 0000-0002-0366-1897 (2014) Paper imbibition for timing of multi-step liquid handling protocols on event-triggered centrifugal microfluidic lab-on-a-disc platforms. RSC Advances, 2015 (5). pp. 1818-1826. ISSN 2046-2069

Rotational microfluidic platforms have attracted swiftly growing interest over the last decade due to their suitability for integration and automation of sample preparation and detection. Valving is of pivotal importance on these compact “Lab-on-a-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______119::55fdfd046688111ad0c4751693c82829
http://doras.dcu.ie/20451/

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Auto-actuated sequential relelase valves for lab-on-a-disc systems

Autor: Kinahan, David J., Kearney, Sinéad M., Ducrée, Jens

Publikováno v: Kinahan, David J. ORCID: 0000-0003-1968-2016 , Kearney, Sinéad M. and Ducrée, Jens ORCID: 0000-0002-0366-1897 (2013) Auto-actuated sequential relelase valves for lab-on-a-disc systems. In: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, 16-20 June 2013, Barcelona, Spain.

In microfluidic biomedical systems valving is often of critical importance for process control. In centrifugal microfluidics valves are typically actuated through changing the centrifugal force seen by the working liquid. Here we present for the firs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______119::43fb23efb414669b31694dce9fed9803
http://doras.dcu.ie/18642/

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Concentration of white blood cells from whole blood by dual centrifugo-pneumatic siphoning with density gradient medium

Autor: Kinahan, David J., Glynn, Macdara, Kearney, Sinéad M., Ducrée, Jens

Publikováno v: Kinahan, David J. ORCID: 0000-0003-1968-2016 , Glynn, Macdara ORCID: 0000-0002-6347-4348 , Kearney, Sinéad M. and Ducrée, Jens ORCID: 0000-0002-0366-1897 (2012) Concentration of white blood cells from whole blood by dual centrifugo-pneumatic siphoning with density gradient medium. In: The 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2012 Conference, 28 Oct-1 Nov 2012, Okinawa, Japan.

Due to the pervasiveness of HIV infections in developing countries there exists a need for a low-cost, user-friendly point-of-care device which can be used to monitor the concentration of T-lymphocytes in the patient’s blood expressing the CD4+ epi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______119::1c3ec13e2fd21fbb4b6e001b4643fc2c
http://doras.dcu.ie/17751/

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