Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Ke-wei Zheng"'
Autor:
Xinyu Yue, Cailing Zhong, Rui Cao, Sizhe Liu, Zhiran Qin, Lin Liu, Yanmei Zhai, Wanyu Luo, Yikai Lian, Mengjie Zhang, Hongjie Lu, Yuanyuan Wang, Mengxin Xu, Shuning Liu, Kexin Lv, Yuzhu Sun, Xingchen Zhu, Haoting Mai, Jing Liao, Jingyi Yang, Lei Deng, Yang Liu, Caijun Sun, Ke-Wei Zheng, Yuelong Shu, Yao-Qing Chen
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-13 (2024)
Abstract Developing broad-spectrum influenza vaccines is crucial for influenza control and potential pandemic preparedness. Here, we reported a novel vaccine design utilizing circular RNA (circRNA) as a delivery platform for multi-subtype neuraminida
Externí odkaz:
https://doaj.org/article/3b33c6f066214697a0b41828305ef925
Autor:
Jingxian Li, Bingjie Zhou, Shiting Wang, Jiayi Ouyang, Xinyi Jiang, Chenglin Wang, Teng Zhou, Ke-wei Zheng, Junqing Wang, Jiaqi Wang
Publikováno v:
Bioengineering, Vol 11, Iss 4, p 381 (2024)
Nanobodies have emerged as promising tools in biomedicine due to their single-chain structure and inherent stability. They generally have convex paratopes, which potentially prefer different epitope sites in an antigen compared to traditional antibod
Externí odkaz:
https://doaj.org/article/28f0a6c09f2d4e03898f87a7d052b3b7
Publikováno v:
ACS Omega, Vol 5, Iss 38, Pp 24666-24673 (2020)
Externí odkaz:
https://doaj.org/article/d474265a85494bb78b907c15e5b314c2
Publikováno v:
Nucleic Acids Research
G-quadruplex is an essential element in gene transcription that serves as a promising drug target. Guanine-vacancy-bearing G-quadruplex (GVBQ) is a newly identified G-quadruplex that has distinct structural features from the canonical G-quadruplex. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5608f6e16b0b47b8e5785945ec591f
https://doi.org/10.1093/nar/gkab1154
https://doi.org/10.1093/nar/gkab1154
Publikováno v:
Nucleic Acids Research
A significant number of sequences in the human genome form noncanonical G-quadruplexes (G4s) with bulges or a guanine vacancy. Here, we systematically characterized the mechanical stability of parallel-stranded G4s with a one to seven nucleotides bul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::125d8efe48d4f066191f4bec807ebeab
https://doi.org/10.1093/nar/gkab531
https://doi.org/10.1093/nar/gkab531
Autor:
Ke-wei Zheng, Jia-Yuan Gong, Juan-Nan Chen, Yong Zhao, Yu-hua Hao, Cui-Jiao Wen, Zheng Tan, Yi-de He, Jia-yu Zhang
Publikováno v:
Nucleic Acids Research
G-quadruplex (G4) structures formed by guanine-rich nucleic acids are implicated in essential physiological and pathological processes and serve as important drug targets. The genome-wide detection of G4s in living cells is important for exploring th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eabf6f1b382a45f28a80c24a12f3eb84
http://europepmc.org/articles/PMC7672459
http://europepmc.org/articles/PMC7672459
Publikováno v:
Chemical Communications. 56:6567-6570
A dual-functional peptide-PNA (peptide nucleic acid) conjugate consisting of a PNA G3-tract and an RHAU23 peptide is devised to target nucleic acids bearing three tandem guanine tracts (G-tracts). The PNA G3-tract joins the three G-tracts to form a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34aa99fd6c2a300af43a6b0140202dda
https://doi.org/10.1039/d0cc02102d
https://doi.org/10.1039/d0cc02102d
Autor:
Ting-ting Cai, Hui-ting Liang, Yi-de He, Jiaqi Wang, Qingyang Zhao, Cheng-lin Wang, Ke-wei Zheng
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ff5a11e0a8d257ea4449761d0132d07
https://doi.org/10.2139/ssrn.4124043
https://doi.org/10.2139/ssrn.4124043
Autor:
Juan-Nan Chen, Cui-Jiao Wen, Ming-Liang Tang, Jia-Yuan Gong, Zheng Tan, Rui-Fang Duan, Yu-hua Hao, Yi-de He, Jia-yu Zhang, Ke-wei Zheng, Su-Ping Ren, Qun Yu
Publikováno v:
Proc Natl Acad Sci U S A
G-quadruplexes (G4s) formed by guanine-rich nucleic acids play a role in essential biological processes such as transcription and replication. Besides the >1.5 million putative G-4–forming sequences (PQSs), the human genome features >640 million si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e13956de9ba46cccb9e638a4a9f3e61f
https://doi.org/10.1073/pnas.2013230118
https://doi.org/10.1073/pnas.2013230118
Emerging evidence suggests that PIWI-interacting RNAs (piRNAs) are one of the most influential small non-coding RNAs (ncRNAs) that regulate RNA silencing. piRNA and PIWI proteins have been confirmed for disease diagnosis and treatment as novel biomar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2e932d3e454713ee818edda376f4fe5
https://doi.org/10.1101/2020.07.02.185611
https://doi.org/10.1101/2020.07.02.185611
