Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ke-Nan Zhang"'
Autor:
Shuai Zhu, Zihao Ye, Ming-Jie Chen, Lei Wang, Yu-Zhuo Wang, Ke-Nan Zhang, Wen-Bo Li, Han-Ming Ding, Zhiming Li, Junliang Zhang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Recently, the asymmetric bifunctionalization of alkenes has received much attention. However, the development of enantioselective alkoxyalkenylation has posed a considerable challenge and has lagged largely behind. Herein, we report a new pa
Externí odkaz:
https://doaj.org/article/09a12e3c0c3a4055875455d53849de6f
Autor:
Si Sun, Changlin Yang, Kuanyu Wang, Ruoyu Huang, Ke-nan Zhang, Yanwei Liu, Zhi Cao, Zheng Zhao, Tao Jiang
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Polymerase I and transcript release factor (PTRF) plays a role in the regulation of gene expression and the release of RNA transcripts during transcription, which have been associated with various human diseases. However, the role of PTRF in
Externí odkaz:
https://doaj.org/article/dc42fc63beea4760a4a0286ebd21bf45
Autor:
Zheng Zhao, Ke-Nan Zhang, Zhiyan Sun, Changlin Yang, Qiangwei Wang, Guanzhang Li, Zhiliang Wang, Fan Zeng, Ruichao Chai, Zenghui Qian, Zheng Wang, Yanwei Liu, Wenping Ma, Fan Wu, Tao Jiang
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-8 (2022)
Measurement(s) glioma Technology Type(s) Whole Exome Sequencing Sample Characteristic - Organism Homo sapiens
Externí odkaz:
https://doaj.org/article/8a64322bea98490594ae1f6ca30d8eb0
Autor:
Rui-Chao Chai, Yu-Zhou Chang, Xin Chang, Bo Pang, Song Yuan An, Ke-Nan Zhang, Yuan-Hao Chang, Tao Jiang, Yong-Zhi Wang
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-16 (2021)
Abstract Background The prognosis for diffuse gliomas is very poor and the mechanism underlying their malignant progression remains unclear. Here, we aimed to elucidate the role and mechanism of the RNA N6,2′-O-dimethyladenosine (m6A) reader, YTH N
Externí odkaz:
https://doaj.org/article/2e2649ec68d14cc88e5420d0becd1d92
Autor:
Rui-Chao Chai, Ning Wang, Yu-Zhou Chang, Ke-Nan Zhang, Jing-Jun Li, Jun-Jie Niu, Fan Wu, Yu-Qing Liu, Yong-Zhi Wang
Publikováno v:
Cancer Cell International, Vol 19, Iss 1, Pp 1-13 (2019)
Abstract Background Abnormal expression of the eukaryotic initiation factor 3 (eIF3) subunits plays critical roles in tumorigenesis and progression, and also has potential prognostic value in cancers. However, the expression and clinical implications
Externí odkaz:
https://doaj.org/article/505ba8246d494af8bab8f35b6ccbbb50
Autor:
Yu-Zhou Chang, Guan-Zhang Li, Bo Pang, Ke-Nan Zhang, Xiao-Hui Zhang, Yong-Zhi Wang, Zhong-li Jiang, Rui-Chao Chai
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Isocitric dehydrogenase (IDH)-wild type diffuse gliomas, which have a poorer prognosis than their IDH-mutant counterparts, are also accompanied with high heterogeneity. Here, we aimed to identify the key biological processes associated with the three
Externí odkaz:
https://doaj.org/article/11a7d0a737364356bc0bffadb523be1e
Autor:
Rui-Chao Chai, Yu-Zhou Chang, Qiang-Wei Wang, Ke-Nan Zhang, Jing-Jun Li, Hua Huang, Fan Wu, Yu-Qing Liu, Yong-Zhi Wang
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Glioblastoma (GBM) is the most malignant glioma, with a median overall survival (OS) of 14–16 months. Temozolomide (TMZ) is the first-line chemotherapy drug for glioma, but whether TMZ should be withheld from patients with GBMs that lack O6-methylg
Externí odkaz:
https://doaj.org/article/7ef1f90bf01145e0948a4a86fd4b4b0e
Publikováno v:
Open Life Sciences, Vol 11, Iss 1, Pp 105-109 (2016)
It is already known that long non-coding RNA growth arrest-specific 5 (GAS5) is downregulated in human colorectal cancer (CRC) cells inhibiting cell proliferation. We further analyzed its involvement in cell cycle distribution and apoptosis induction
Externí odkaz:
https://doaj.org/article/8b8d5bb05db7447ebd61f83cc264a197
Autor:
Junliang Zhang, Shuai Zhu, Zihao Ye, Ming-Jie Chen, Lei Wang, Yu-Zhuo Wang, Ke-Nan Zhang, Wenbo Li, Han-Ming Ding, Zhiming Li
Recently, the asymmetric bifunctionalization of alkenes has received much attention. However, the development of enantioselective alkoxyalkenylation has posed a considerable challenge and has lagged largely behind. Herein, we report a novel palladium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f062020836ebdbd9e8e654ae28602b2e
https://doi.org/10.21203/rs.3.rs-2857175/v1
https://doi.org/10.21203/rs.3.rs-2857175/v1
Autor:
Ke-Nan Zhang, Zheng Zhao, Jing Chen, Zhaoshi Bao, Rui-Chao Chai, Zhiyan Sun, Lingxiang Wu, Zhiliang Wang, Hanjie Liu, Quanhua Mu, Huimin Hu, Fan Zeng, Zheng Wang, Guanzhang Li, Yuanhao Chang, Qiangwei Wang, Fan Wu, Ying Zhang, Yuqing Liu, Chunjie Jiang, Ulf Dietrich Kahlert, Do-Hyun Nam, Wei Zhang, Chunsheng Kang, Jiguang Wang, Rongjie Tao, Qianghu Wang, Tao Jiang
Publikováno v:
Holistic Integrative Oncology. 1
Purpose Our previous study has shown that PTPRZ1-MET (ZM) fusion is a viable target for MET inhibitors in gliomas. However, the diversity and prevalence of somatic MET alterations in diffuse gliomas are still elusive and need to be extensively charac