Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Ke-Jie Du"'
Autor:
Johannes Karges, Fangmian Wei, Hui Chao, Ying Zhou, Mingwei Lin, Liang-Nian Ji, Jinchao Shen, Kai Xiong, Yu Chen, Jun-Feng Kou, Ke-Jie Du
Publikováno v:
ACS Applied Materials & Interfaces. 13:38959-38968
Chemotherapy continues to be the most commonly applied strategy for cancer. Despite the impressive clinical success obtained with several drugs, increasing numbers of (multi)drug-resistant tumors are reported. To overcome this shortcoming, novel drug
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1871:140897
Autor:
Ke-Jie Du, Yonghua Wang, Ge-Bo Wen, Chuan-Wan Wei, Ying-Wu Lin, Hong Yuan, Jia-Jia Lang, Jie Luo
Publikováno v:
ACS Catalysis. 10:14359-14365
Design of artificial nucleases is essential in biotechnology and biomedicine, whereas few artificial nucleases can both cleave and degrade DNA molecules. Heme proteins are potential enzymes for DNA...
Publikováno v:
SSRN Electronic Journal.
Heme proteins have recently emerged as promising artificial metalloenzymes for catalyzing diverse reactions. In this report, L29E Mb, a single mutant of myoglobin (Mb), was reconstituted by replacing the heme with a sodium copper cholorophyllin (CuCP
Autor:
Can Liu, Hong Yuan, Fei Liao, Chuan-Wan Wei, Ke-Jie Du, Shu-Qin Gao, Xiangshi Tan, Ying-Wu Lin
Publikováno v:
Chemical Communications. 55:6610-6613
The X-ray crystal structure of F43Y/T67R myoglobin revealed unique Tyr-heme double cross-links between Tyr43 and the heme 4-vinyl group, which represents a novel post-translational modification of heme proteins. Moreover, with the feature of a distal
Publikováno v:
Journal of Molecular Structure. 1138:155-160
A new polynuclear Cu(II) compound, [Cu4(bpy)4(OH)4(H2O)(BTC)]NO3·8H2O (1), was prepared by self-assembly from the solution of copper(II) nitrate and two kinds of ligands, 2,2′-bipyridine (bpy) and benzene-tricarboxylic acid (H3BTC). Single crystal
Publikováno v:
ChemistryOpen. 6:325-330
The design of artificial metalloenzymes has achieved tremendous progress, although few designs can achieve catalytic performances comparable to that of native enzymes. Moreover, the structure and function of artificial metalloenzymes in non-native st
Autor:
Bo He, sup> 南华大学化学化工学院, 湖南 衡阳 ,, Ying-Wu Lin, Ke-Jie Du, Ge-Bo Wen, Shu-Qin Gao, Chang-Ming Nie, sup> 南华大学蛋白质结构与功能实验室, 湖南 衡阳 ,
Publikováno v:
University Chemistry. 32:42-46
Publikováno v:
Inorganic Chemistry Frontiers. 4:2033-2036
Myoglobin with a redesigned active center was constructed and reconstituted with zinc protoporphyrin (ZnPP), which was shown to exhibit novel photo-induced DNA cleavage activities, involving a hydroxyl radical (˙OH) with a minor contribution from si