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Akademický článek

Rapid detection of sacbrood virus (SBV) by one-step reverse transcription loop-mediated isothermal amplification assay

Autor: Jin-Long Yang, Rui Yang, Ke-Fei Shen, Xiang-Wei Peng, Tao Xiong, Zuo-Hua Liu

Publikováno v: Virology Journal, Vol 9, Iss 1, p 47 (2012)

Abstract Background Sacbrood virus (SBV) primarily infects honeybee broods, and in order to deal with the problem cost effective detection methods are required. Findings A one-step reverse transcription loop-mediated isothermal amplification (RT-LAMP

Externí odkaz: https://doaj.org/article/353fd4a842784a3581b83b2d61bf3f28

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Low doses of cyclic AMP-phosphodiesterase inhibitors rapidly evoke opioid receptor-mediated thermal hyperalgesia in naïve mice which is converted to prominent analgesia by cotreatment with ultra-low-dose naltrexone

Autor: Stanley M. Crain, Ke-Fei Shen

Publikováno v: Brain Research. 1231:16-24

Systemic (s.c.) injection in naive mice of cyclic AMP-phosphodiesterase (cAMP-PDE) inhibitors, e.g. 3-isobutyl-1-methylxanthine [(IBMX) or caffeine, 10 mg/kg] or the more specific cAMP-PDE inhibitor, rolipram (1 μg/kg), rapidly evokes thermal hypera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::928c7ee93db23824e7b2c9541ca9f449
https://doi.org/10.1016/j.brainres.2008.07.015

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Naloxone rapidly evokes endogenous kappa opioid receptor-mediated hyperalgesia in naïve mice pretreated briefly with GM1 ganglioside or in chronic morphine-dependent mice

Autor: Ke-Fei Shen, Stanley M. Crain

Publikováno v: Brain Research. 1167:31-41

Low-dose naloxone-precipitated withdrawal hyperalgesia is a reliable indicator of physical dependence after chronic morphine treatment. A remarkably similar long-lasting (>3-4 h) hyperalgesia is evoked by injection of a low dose of naloxone (10 micro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::790dfa1e1ae06763d37679d7411d62dd
https://doi.org/10.1016/j.brainres.2007.06.058

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Cholera toxin-B subunit blocks excitatory opioid receptor-mediated hyperalgesic effects in mice, thereby unmasking potent opioid analgesia and attenuating opioid tolerance/dependence

Autor: Stanley M. Crain, Ke-Fei Shen

Publikováno v: Brain Research. 919:20-30

In a previous study we demonstrated that injection (i.p.) of low doses of GM1 ganglioside in mice rapidly attenuates morphine's analgesic effects. This result is consonant with our electrophysiologic studies in nociceptive types of dorsal root gangli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a6f7ec96fc074610ee74253b84ab75
https://doi.org/10.1016/s0006-8993(01)02990-0

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Ultra-low doses of naltrexone or etorphine increase morphine's antinociceptive potency and attenuate tolerance/dependence in mice

Autor: Stanley M. Crain, Ke-Fei Shen

Publikováno v: Brain Research. 757:176-190

In previous studies we showed that low (pM) concentrations of naloxone (NLX), naltrexone (NTX) or etorphine selectively antagonize excitatory, but not inhibitory, opioid receptor-mediated functions in nociceptive types of sensory neurons in culture.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77dcda2ca00daa678e87c2f72a6fd9a
https://doi.org/10.1016/s0006-8993(97)00197-2

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Biphalin, an enkephalin analog with unexpectedly high antinociceptive potency and low dependence liability in vivo, selectively antagonizes excitatory opioid receptor functions of sensory neurons in culture

Autor: Stanley M. Crain, Ke-Fei Shen

Publikováno v: Brain Research. 701:158-166

The mechanism of action of the dimeric enkephalin peptide, biphalin (Tyr-D-Ala-Gly-Phe-NH2)2, which was previously shown to have remarkable high antinociceptive potency and low dependence liability in vivo, has now been studied by electrophysiologic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4725a26ae31ca018adb82454a51bfa97
https://doi.org/10.1016/0006-8993(95)00999-1

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Chronic morphine-treated sensory ganglion neurons remain supersensitive to the excitatory effects of naloxone for months after return to normal culture medium: an in vitro model of ‘protracted opioid dependence’

Autor: Stanley M. Crain, Ke-Fei Shen

Publikováno v: Brain Research. 694:103-110

Chronic morphine-treated dorsal-root ganglion (DRG) neurons in DRG/spinal cord explant cultures were previously shown to become supersensitive to the excitatory effects of remarkably low concentrations of the opioid agonists, morphine and dynorphin,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a53a2d507c8a6ce3f5a1dd4c8587dc
https://doi.org/10.1016/0006-8993(95)00773-j

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Nerve growth factor rapidly prolongs the action potential of mature sensory ganglion neurons in culture, and this effect requires activation of Gs-coupled excitatory kappa-opioid receptors on these cells

Autor: S. M. Crain, Ke-Fei Shen

Publikováno v: The Journal of Neuroscience. 14:5570-5579

Application of low concentrations (pM-nM) of NGF to mouse dorsal root ganglion (DRG)-spinal cord explants in long-term organotypic cultures rapidly prolongs the duration of the Ca(2+)-dependent component of the action potential (APD) in a major subse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d326e7648b64b19889b3adfa936e7fab
https://doi.org/10.1523/jneurosci.14-09-05570.1994

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Opioids at low concentration decrease openings of K+ channels in sensory ganglion neurons

Autor: Stanley M. Crain, Ke-Fei Shen, S.-F. Fan

Publikováno v: Brain Research. 558:166-170

Previous studies showed that low concentrations of opioids prolong the calcium-dependent component of the action potential duration (APD) of dorsal root ganglion (DRG) neurons, whereas higher concentrations shorten the APD. In the present study whole

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a28e4131e3fbb91ec465a4044b5e2ee9
https://doi.org/10.1016/0006-8993(91)90737-g

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