Zobrazeno 1 - 10
of 2 453
pro vyhledávání: '"Ke K. Zhang"'
Autor:
Dani Ran Castillo, Daniel Park, Won Jin Jeon, Bowon Joung, Jae Lee, Chieh Yang, Bryan Pham, Christopher Hino, Esther Chong, Andrea Shields, Anthony Nguyen, Joel Brothers, Yan Liu, Ke K. Zhang, Huynh Cao
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 10207 (2023)
Mantle cell lymphoma (MCL) is a type of non-Hodgkin lymphoma (NHL) characterized by a hallmark translocation of t (11; 14). CD10 negativity has been used to differentiate MCL from other NHL types; however, recently, there has been an increase in the
Externí odkaz:
https://doaj.org/article/9c27f4cec48146a095716368b2c9b9b7
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
NAFLD, regarded as the hepatic manifestation of metabolic syndrome, is the most common form of liver disease in the United States. The Odd-skipped related 1 (Osr1) gene was previously reported to play a critical role in embryonic development and as a
Externí odkaz:
https://doaj.org/article/40a047db849e4f8a82eaf881d7173bfe
Autor:
Yi Xu, Lily Tran, Janet Tang, Vinh Nguyen, Elisabeth Sewell, Jeffrey Xiao, Christopher Hino, Samiksha Wasnik, Olivia L. Francis-Boyle, Ke K. Zhang, Linglin Xie, Jiang F. Zhong, David J. Baylink, Chien-Shing Chen, Mark E. Reeves, Huynh Cao
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11387 (2022)
Acute myeloid leukemia (AML)—the most frequent form of adult blood cancer—is characterized by heterogeneous mechanisms and disease progression. Developing an effective therapeutic strategy that targets metabolic homeostasis and energy production
Externí odkaz:
https://doaj.org/article/6d31cd8f2518422694271464b14a8378
Autor:
Hui Peng, Huiting Xu, Jie Wu, Jiangyuan Li, Xian Wang, Zhimin Liu, Minjee Kim, Minsun S. Jeon, Ke K. Zhang, Linglin Xie
Publikováno v:
Nutrients, Vol 14, Iss 12, p 2545 (2022)
Recent studies have suggested that prevention of obesity and non-alcoholic fatty liver disease (NAFLD) should start with maternal dietary management. We previously reported disrupted methionine cycle, associated with NAFLD, in male offspring liver du
Externí odkaz:
https://doaj.org/article/9bd9682239d64f538477656d88f31bc7
Autor:
Christopher Hino, Bryan Pham, Daniel Park, Chieh Yang, Michael H.K. Nguyen, Simmer Kaur, Mark E. Reeves, Yi Xu, Kevin Nishino, Lu Pu, Sue Min Kwon, Jiang F. Zhong, Ke K. Zhang, Linglin Xie, Esther G. Chong, Chien-Shing Chen, Vinh Nguyen, Dan Ran Castillo, Huynh Cao
Publikováno v:
Biomedicines, Vol 10, Iss 6, p 1410 (2022)
The tumor microenvironment (TME) plays an essential role in the development, proliferation, and survival of leukemic blasts in acute myeloid leukemia (AML). Within the bone marrow and peripheral blood, various phenotypically and functionally altered
Externí odkaz:
https://doaj.org/article/7689272f960f44b0be05cc1d06cf9ad9
Autor:
Huynh Cao, Verena Tadros, Benjamin Hiramoto, Kevin Leeper, Christopher Hino, Jeffrey Xiao, Bryan Pham, Do Hyun Kim, Mark E. Reeves, Chien-Shing Chen, Jiang F. Zhong, Ke K. Zhang, Linglin Xie, Samiksha Wasnik, David J. Baylink, Yi Xu
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1038 (2022)
Disease relapse is a common cause of treatment failure in FMS-like tyrosine kinase 3 (FLT3) mutated acute myeloid leukemia (AML). In this study, to identify therapeutic targets responsible for the survival and proliferation of leukemic cells (blasts)
Externí odkaz:
https://doaj.org/article/a2d89bcac6e7403c81113892bef62085
Autor:
Xin Guo, Chang Shu, Honggui Li, Ya Pei, Shih-Lung Woo, Juan Zheng, Mengyang Liu, Hang Xu, Rachel Botchlett, Ting Guo, Yuli Cai, Xinsheng Gao, Jing Zhou, Lu Chen, Qifu Li, Xiaoqiu Xiao, Linglin Xie, Ke K. Zhang, Jun-Yuan Ji, Yuqing Huo, Fanyin Meng, Gianfranco Alpini, Pingwei Li, Chaodong Wu
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Endogenous cyclic GMP-AMP (cGAMP) binds and activates STING to induce type I interferons. However, whether cGAMP plays any roles in regulating metabolic homeostasis remains unknown. Here we show that exogenous cGAMP ameliorates obesity-assoc
Externí odkaz:
https://doaj.org/article/0eb94b4ac1234b1abef97562d680489e
Autor:
Zehuan Ding, Naomi McCauley, Yushu Qin, Lauren Lawless, Shaodong Guo, Lanjing Zhang, Ke K. Zhang, Linglin Xie
Publikováno v:
Laboratory Investigation. 103:100017
Autor:
Hui Peng, Jiangyuan Li, Huiting Xu, Xian Wang, Leya He, Naomi McCauley, Ke K. Zhang, Linglin Xie
Publikováno v:
The Journal of nutritional biochemistry. 111
Little is known if and how maternal diet affects the liver phospholipid profiles that contribute to non-alcoholic fatty liver disease (NAFLD) development in offspring. We examined NAFLD phenotypes in male offspring mice of either maternal normal-fat
Autor:
Xiaorui R. Xiong, Li I. Zhang, Ke Ke K Zhang, Feixue Liang, Huizhong W. Tao, Lukas Mesik, Daniel B. Polley, Haifu Li, Zhongju Xiao
Publikováno v:
Neuron. 79(4):738-753
Summary Binaural integration in the central nucleus of inferior colliculus (ICC) plays a critical role in sound localization. However, its arithmetic nature and underlying synaptic mechanisms remain unclear. Here, we showed in mouse ICC neurons that