Zobrazeno 1 - 10
of 343
pro vyhledávání: '"Ke Jian Liu"'
Autor:
Rachel M. Speer, Shuvro P. Nandi, Karen L. Cooper, Xixi Zhou, Hui Yu, Yan Guo, Laurie G. Hudson, Ludmil B. Alexandrov, Ke Jian Liu
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Arsenic enhances the carcinogenicity of ultraviolet radiation (UVR). However, the mechanisms of arsenic-driven oncogenesis are not well understood. Here, we utilize experimental systems to investigate the carcinogenic and mutagenic propertie
Externí odkaz:
https://doaj.org/article/f2b3976df61a4e12854326502c2e7c85
Publikováno v:
Heliyon, Vol 10, Iss 2, Pp e25052- (2024)
Background: and Purpose: Hemorrhagic transformation (HT) is one of the severe complications in acute ischemic stroke, especially for the patients who undergo recanalization treatment. It is crucial to screen patients who have high risk of HT before r
Externí odkaz:
https://doaj.org/article/85afe4d6ad8e4f08ae2821c6bd150ca6
Autor:
Guanghua Wan, Sebastian Medina, Haikun Zhang, Rong Pan, Xixi Zhou, Alicia M. Bolt, Li Luo, Scott W. Burchiel, Ke Jian Liu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Arsenic exposure poses numerous threats to human health. Our previous work in mice has shown that arsenic causes anemia by inhibiting erythropoiesis. However, the impacts of arsenic exposure on human erythropoiesis remain largely unclear. We
Externí odkaz:
https://doaj.org/article/e38830cfb8fd47e49acfa75a5b9e5b86
Publikováno v:
Brain Hemorrhages, Vol 2, Iss 2, Pp 63-70 (2021)
Although recanalization via thrombolysis and/or thrombectomy has proven to be a beneficial treatment for ischemic stroke, their application are severely limited due to increased risk of symptomatic intracerebral hemorrhage (ICH) as a result of ongoin
Externí odkaz:
https://doaj.org/article/e44280db94274712886374e551776fc1
Autor:
Weili Li, Jiayue Ding, Xueqin Sui, Zhifeng Qi, Longfei Wu, Chenghe Sun, Kangxiang Ji, Qingfeng Ma, Xunming Ji, Ke Jian Liu
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 4, Pp 420-428 (2020)
Abstract Objective This study evaluates reocclusion prognostic outcomes and explores reocclusion risk factors after mechanical thrombectomy (MT) in Chinese stroke patients. Methods Altogether, 614 patients with AIS with successful recanalization afte
Externí odkaz:
https://doaj.org/article/3ae2a1e0cb2f41268691e79141d685e7
Publikováno v:
Brain Circulation, Vol 6, Iss 3, Pp 152-162 (2020)
Occludin is a key structural component of the blood–brain barrier (BBB) that has recently become an important focus of research in BBB damages. Many studies have demonstrated that occludin could regulate the integrity and permeability of the BBB. T
Externí odkaz:
https://doaj.org/article/87f7c059d8104fb38ab93779cbb392e5
Autor:
Sebastian Medina, Haikun Zhang, Laura V. Santos-Medina, Zachary A. Yee, Kaitlin J. Martin, Guanghua Wan, Alicia M. Bolt, Xixi Zhou, Miroslav Stýblo, Ke Jian Liu
Publikováno v:
Water, Vol 15, Iss 3, p 448 (2023)
Chronic arsenic exposures via the consumption of contaminated drinking water are clearly associated with many deleterious health outcomes, including anemia. Following exposure, trivalent inorganic arsenic (AsIII) is methylated through a series of ars
Externí odkaz:
https://doaj.org/article/1797031524214ca48b0ec40f367bb054
Autor:
Shuhua Yuan, Weili Li, Chengbei Hou, Huining Kang, Qingfeng Ma, Xunming Ji, Zhifeng Qi, Ke Jian Liu
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Hemorrhagic transformation (HT) is a severe complication following acute ischemic stroke, particularly with reperfusion interventions, leading to poor prognosis. Serum occludin level is related with blood brain barrier disruption, and the National In
Externí odkaz:
https://doaj.org/article/7dbf7351c7b8466ca85b5b137d35673c
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Hemorrhagic transformation (HT), which occurs with or without reperfusion treatments (thrombolysis and/or thrombectomy), deteriorates the outcomes of ischemic stroke patients. It is essential to find clinically reliable biomarkers that can predict HT
Externí odkaz:
https://doaj.org/article/8e6cced5c3e84f94bb545d16a0d04a20
Publikováno v:
Brain Circulation, Vol 4, Iss 4, Pp 145-152 (2018)
Ischemic stroke is a leading cause of death and disability. Fear of intracranial hemorrhage (ICH) has been the primary reason for withholding tissue plasminogen activator (tPA) and thrombectomy, the only two widely accepted treatments for ischemic st
Externí odkaz:
https://doaj.org/article/a7eec09e9c9c402682e12b9979c6e86b