Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Ke‐Zheng Dai"'
Autor:
Saskia Meyer, Isaac Blaas, Ravi Chand Bollineni, Marina Delic-Sarac, Trung T. Tran, Cathrine Knetter, Ke-Zheng Dai, Torfinn Støve Madssen, John T. Vaage, Alice Gustavsen, Weiwen Yang, Lise Sofie Haug Nissen-Meyer, Karolos Douvlataniotis, Maarja Laos, Morten Milek Nielsen, Bernd Thiede, Arne Søraas, Fridtjof Lund-Johansen, Even H. Rustad, Johanna Olweus
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111995- (2023)
Summary: The emergence of SARS-CoV-2 variants of concern (VOC) is driven by mutations that mediate escape from neutralizing antibodies. There is also evidence that mutations can cause loss of T cell epitopes. However, studies on viral escape from T c
Externí odkaz:
https://doaj.org/article/8f80035bd4194790bb08bebf65988c88
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Measuring degranulation through CD107a expression has become an advantageous tool for testing the functional capacity of cytotoxic cells. Such functional studies have been hampered in the rat by the lack of a suitable anti-rat CD107a antibody. In thi
Externí odkaz:
https://doaj.org/article/5d20a56d2c4d4ef58491964c89933015
Autor:
Jon Riise, Saskia Meyer, Isaac Blaas, Adity Chopra, Trung T. Tran, Marina Delic‐Sarac, Malu Lian Hestdalen, Ellen Brodin, Even Holth Rustad, Ke‐Zheng Dai, John Torgils Vaage, Lise Sofie Haug Nissen‐Meyer, Fredrik Sund, Karin F. Wader, Anne T. Bjornevik, Peter A. Meyer, Gro O. Nygaard, Marton König, Sigbjørn Smeland, Fridtjof Lund‐Johansen, Johanna Olweus, Arne Kolstad
Publikováno v:
British Journal of Haematology
B-cell depletion induced by anti-cluster of differentiation 20 (CD20) monoclonal antibody (mAb) therapy of patients with lymphoma is expected to impair humoral responses to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) vaccination, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::734eb99dd6ec166edc365c141fd1ed99
http://hdl.handle.net/10852/97611
http://hdl.handle.net/10852/97611
Autor:
Karolos Douvlataniotis, Fridtjof Lund-Johansen, Bernd Thiede, Alice Gustavsen, Saskia Meyer, Morten Milek Nielsen, Maarja Laos, Ke-Zheng Dai, Torfinn Støve Madssen, Cathrine Knetter, Trung Tran, Even H. Rustad, Weiwen Yang, Arne Søraas, Lise Sofie H. Nissen-Meyer, Isaac Blaas, Ravi Chand Bollineni, Johanna Olweus, Marina Delic-Sarac, John T. Vaage
T-cell epitopes with broad population coverage may form the basis for a new generation of SARS-CoV-2 vaccines. However, published studies on immunoprevalence are limited by small test cohorts, low frequencies of antigen-specific cells and lack of dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9212d3d4e3e178bc4d2d86c3d22ee41f
https://doi.org/10.1101/2021.10.13.463911
https://doi.org/10.1101/2021.10.13.463911
Publikováno v:
The Journal of Immunology. 200:2847-2859
Early studies indicate that rats may have a repertoire of MHC class Ib–reactive Ly49 stimulatory receptors capable of mounting memory-like NK cell alloresponses. In this article, we provide molecular and functional evidence for this assumption. Pai
Autor:
James C. Ryan, Michael R. Daws, Ke-Zheng Dai, Christian Naper, Hamid Shegarfi, Bent Rolstad, John T. Vaage
Publikováno v:
Journal of Leukocyte Biology. 89:617-623
Ly49 receptors in rodents, like KIRs in humans, regulate NK cell activity. Although inhibitory Ly49 receptors clearly recognize MHC-I molecules, ligands for the activating Ly49 receptors are less well defined. Here, we show that the activating Ly49s4
Autor:
Anne Spurkland, Monika Forsbring, Øyvind Molberg, Vibeke Sundvold-Gjerstad, Karl Schenck, Hans Christian Aasheim, Kristin M. Kolltveit, Karoline W. Schjetne, B. Bogen, Stine Granum, Ke Zheng Dai, Finn-Eirik Johansen, Virginia Smith Shapiro
Publikováno v:
Molecular Immunology. 45:2380-2390
The T-cell specific adapter protein (TSAd) encoded by the SH2D2A gene is up-regulated in activated human CD4+ T-cells in a cAMP-dependent manner. Expression of SH2D2A is important for proper activation of T-cells. Here, we show that SH2D2A expression
Autor:
Anton Martens, Haakon B. Benestad, Bente K. Omdal, John T. Vaage, Janne Nestvold, Ke-Zheng Dai, Bent Rolstad
Publikováno v:
Transplantation. 85:102-111
We have employed a rat model for human acute myeloid leukemia, a promyelocytic leukemia in the BN rat strain (BNML), to develop new protocols for immunotherapy in combination with allogeneic bone marrow transplantation (alloBMT). The status of mixed
Autor:
Lise Kveberg, Christian Naper, James C. Ryan, Marit Inngjerdingen, Ke-Zheng Dai, Camilla J. Bäck, Bent Rolstad, John T. Vaage
Publikováno v:
The Journal of Immunology. 176:4133-4140
The proximal region of the NK gene complex encodes the NKR-P1 family of killer cell lectin-like receptors which in mice bind members of the genetically linked C-type lectin-related family, while the distal region encodes Ly49 receptors for polymorphi
Autor:
Frode Vartdal, Finn-Eirik Johansen, Kristin M. Kolltveit, Ke-Zheng Dai, Zlatko Dembic, Anne Spurkland, Hans Christian Aasheim
Publikováno v:
The Journal of Immunology. 172:6144-6151
The SH2D2A gene, encoding the T cell-specific adapter protein (TSAd), is rapidly induced in activated T cells. In this study we investigate the regulation of the SH2D2A gene in Jurkat T cells and in primary T cells. Reporter gene assays demonstrated