Selecting instruments for Mendelian randomization in the wake of genome-wide association studies

Autor: Di, Swerdlow, Kb, Kuchenbaecker, Shah S, Sofat R, Mv, Holmes, White J, Js, Mindell, Kivimaki M, Ej, Brunner, John Whittaker, Jp, Casas, Ad, Hingorani

Publikováno v: Europe PubMed Central

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::606b2460a332ea14a9f94dfeccd6aa78
http://europepmc.org/abstract/med/27342221

Publisher Correction: Shared heritability and functional enrichment across six solid cancers.

Autor: Jiang X; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, 677 Huntington Ave, Boston, MA, 02115, USA. xiajiang@hsph.harvard.edu.; Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Nobels vagen 13, 17177, Stockholm, Sweden. xiajiang@hsph.harvard.edu., Finucane HK; Department of Epidemiology, Harvard T.H. Chan School of Public Health, 677 Huntington Ave, Boston, MA, 02115, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, 75 Ames St, Cambridge, MA, 02142, USA., Schumacher FR; Department of Population and Quantitative Health Sciences, Case Western Reserve University, 10900 Eucid Avenue, Cleveland, OH, 44106, USA.; Seidman Cancer Center, University Hospitals, Cleveland, OH, 44106, USA., Schmit SL; Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Dr. MRC-CANCONT, Tampa, FL, 33612, USA.; Department of Gastrointestinal Oncology, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Dr. MRC-CANCONT, Tampa, FL, 33612, USA., Tyrer JP; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, 2 Worts' Causeway, Cambridge, CB1 8RN, UK., Han Y; Department of Biomedical Data Science, The Geisel School of Medicine at Dartmouth, 1 Medical Center Drive, Lebanon, NH, 03756, USA., Michailidou K; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, 2 Worts' Causeway, Cambridge, CB1 8RN, UK.; Department of Electron Microscopy/Molecular Pathology, The Cyprus Institute of Neurology and Genetics, 1683, Nicosia, Cyprus., Lesseur C; Genetic Epidemiology Group, International Agency for Research on Cancer, 150 Cours Albert Thomas, 69008, Lyon, France.; Section of Genetics, International Agency for Research on Cancer, 150 cours Albert Thomas, 69008, Lyon, France., Kuchenbaecker KB; Division of Psychiatry, University College London, Maple House, 149 Tottenham Court Road, London, W1T 7NF, UK.; UCL Genetics Institute, University College London, Gower Street, London, WC1E 6BT, UK., Dennis J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, 2 Worts' Causeway, Cambridge, CB1 8RN, UK., Conti DV; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, 48109, USA., Casey G; Public Health Sciences, University of Virginia, P.O. Box 800717, Charlottesville, VI, 22908, USA.; Center for Public Health Genomics, University of Virginia, P.O. Box 800717, Charlottesville, VI, 22908, USA., Gaudet MM; Epidemiology Research Program, American Cancer Society, 250 Williams Street NW, Atlanta, GA, 30303, USA., Huyghe JR; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA, 98109-1024, USA., Albanes D; Division of Cancer Epidemiology and Genetics, National Cancer Institute, 9609 Medical Center Dr, Rockville, MD, 20850, USA., Aldrich MC; Department of Thoracic Surgery, Division of Epidemiology, Vanderbilt University Medical Center, 609 Oxford House, Nashville, TN, 37232, USA., Andrew AS; Department of Neurology, Dartmouth-Hitchcock Medical Center, 7927 Rubin Building, Room 860, One Medical Center Drive, Lebanon, NH, 3756, USA., Andrulis IL; Fred ALitwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, 600 University Avenue, Toronto, ON, M5G1X5, Canada.; Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, ON, M5S1A8, Canada., Anton-Culver H; Department of Epidemiology, Genetic Epidemiology Research Institute, University of California Irvine, 224 Irvine Hall, Irvine, CA, 92617, USA., Antoniou AC; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, 2 Worts' Causeway, Cambridge, CB1 8RN, UK., Antonenkova NN; NNAlexandrov Research Institute of Oncology and Medical Radiology, Settlement of Lesnoy-2, 223040, Minsk, Belarus., Arnold SM; Markey Cancer Center, University of Kentucky, 800 Rose Street, cc445, Lexington, KY, 40508, USA., Aronson KJ; Department of Public Health Sciences, and Cancer Research Institute, Queen's University, 10 Stuart Street, Kingston, ON, K7L 3N6, Canada., Arun BK; Department of Breast Medical Oncology, University of Texas MD Anderson Cancer Center, 1155 Pressler St, Houston, TX, 77030, USA., Bandera EV; Cancer Prevention and Control Program, Rutgers Cancer Institute of New Jersey, 195 Little Albany Street, Room 5568, New Brunswick, NJ, 08903, USA., Barkardottir RB; Department of Pathology, Landspitali University Hospital, Hringbraut, Reykjavik, 101, Iceland.; BMC (Biomedical Centre), Faculty of Medicine, University of Iceland, Vatnsmyrarvegi 16, Reykjavik, 101, Iceland., Barnes DR; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, 2 Worts' Causeway, Cambridge, CB1 8RN, UK., Batra J; Australian Prostate Cancer Research Centre-Qld, Translational Research Institute, 37 Kent St, Woolloongabba, QLD, 4102, Australia.; Institute of Health and Biomedical Innovation and School of Biomedical Science, Queensland University of Technology, 60 Musk Ave, Kelvin Grove, QLD, 4059, Australia., Beckmann MW; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen Nuremberg, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Universitaetsstrasse 21-23, 91054, Erlangen, Germany., Benitez J; Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Calle de Melchor Fernández Almagro, 3, 28029, Madrid, Spain.; Biomedical Network on Rare Diseases (CIBERER), AvMonforte de Lemos, 3-5Pabellón 11Planta 0, 28029, Madrid, Spain., Benlloch S; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, 2 Worts' Causeway, Cambridge, CB1 8RN, UK.; Division of Genetics and Epidemiology, The Institute of Cancer Research, 15 Cotswold Road, London, SM2 5NG, UK., Berchuck A; Department of Obstetrics and Gynecology, Duke University Medical Center, 25171 Morris Bldg, Durham, NC, 27710, USA., Berndt SI; Division of Cancer Epidemiology and Genetics, National Cancer Institute, 9609 Medical Center Dr, Rockville, MD, 20850, USA., Bickeböller H; Department of Genetic Epidemiology, University Medical Center Goettingen, Humboldtallee 32, 37073, Goettingen, Germany., Bien SA; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA, 98109-1024, USA.; School of Public Health, University of Washington, 1959 NE Pacific Street, Health Science Buidling, F-350, Seattle, WA, 98195, USA., Blomqvist C; Department of Oncology, Helsinki University Hospital, University of Helsinki, Haartmaninkatu 4, 00290, Helsinki, Finland.; Department of Oncology, Örebro University Hospital, 70185, Örebro, Sweden., Boccia S; Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168, Roma, Italy.; Università Cattolica del Sacro Cuore, 00168, Roma, Italy., Bogdanova NV; NNAlexandrov Research Institute of Oncology and Medical Radiology, Settlement of Lesnoy-2, 223040, Minsk, Belarus.; Department of Radiation Oncology, Hannover Medical School, Carl-Neuberg-Straße 1, 30625, Hannover, Germany.; Gynaecology Research Unit, Hannover Medical School, Carl-Neuberg-Straße 1, 30625, Hannover, Germany., Bojesen SE; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev Ringvej 75, 2730, Herlev, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev Ringvej 75, 2730, Herlev, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark., Bolla MK; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, 2 Worts' Causeway, Cambridge, CB1 8RN, UK., Brauch H; DrMargarete Fischer-Bosch-Institute of Clinical Pharmacology, Auerbachstr112, 70376, Stuttgart, Germany.; University of Tübingen, Geschwister-Scholl-Platz, 72074, Tübingen, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany., Brenner H; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany., Brenton JD; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, CB2 0RE, Cambridge, UK., Brook MN; Division of Genetics and Epidemiology, The Institute of Cancer Research, 15 Cotswold Road, London, SM2 5NG, UK., Brunet J; Genetic Counseling Unit, Hereditary Cancer Program, IDIBGI (Institut d'Investigació Biomèdica de Girona), Catalan Institute of Oncology, CIBERONC, AvFrança s/n, 17007, Girona, Spain., Brunnström H; Clinical Sciences, Lund University, Box 117, 221 00, Lund, Sweden.; Department of Genetics and Pathology, Division of Laboratory Medicine, 221 85, Lund, Sweden., Buchanan DD; University of Melbourne Centre for Cancer Research, Victorian Comprehensive Cancer Centre, Parkville, VIC, 3010, Australia.; Colorectal Oncogenomics Group, Department of Clinical Pathology, The University of Melbourne, Parkville, VIC, 3010, Australia.; Genomic Medicine and Family Cancer Clinic, Royal Melbourne Hospital, Parkville, VIC, 3010, Australia., Burwinkel B; Department of Obstetrics and Gynecology, University of Heidelberg, Im Neuenheimer Feld 440, 69120, Heidelberg, Germany.; Molecular Epidemiology Group, C080, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany., Butzow R; Department of Pathology, University of Helsinki and Helsinki University Hospital, Biomedicum Helsinki 4th Floor, Haartmaninkatu 8, 00029, Helsinki, Finland., Cadoni G; Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168, Roma, Italy.; Università Cattolica del Sacro Cuore, 00168, Roma, Italy., Caldés T; Medical Oncology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Centro Investigación Biomédica en Red de Cáncer (CIBERONC), Calle del Prof Martín Lagos, 28040, Madrid, Spain., Caligo MA; Section of Genetic Oncology, Department of Laboratory Medicine, University and University Hospital of Pisa, via Roma 67, 56126, Pisa, Italy., Campbell I; Peter MacCallum Cancer Center, 305 Grattan Street, Melbourne, VIC, 3000, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, 305 Grattan Street, Melbourne, VIC, 3000, Australia., Campbell PT; Epidemiology Research Program, American Cancer Society, 250 Williams Street NW, Atlanta, GA, 30303, USA., Cancel-Tassin G; Sorbonne Université, GRC N°5 ONCOTYPE-URO, Tenon Hospital, 75020, Paris, France.; CeRePP, Tenon Hospital, 75020, Paris, France., Cannon-Albright L; Division of Genetic Epidemiology, Department of Medicine, University of Utah School of Medicine, Salt Lake City, UT, 84112, USA.; George EWahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, 84112, USA., Campa D; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.; Department of Biology, University of Pisa, 56126, Pisa, Italy., Caporaso N; Division of Cancer Epidemiology and Genetics, National Cancer Institute, 9609 Medical Center Dr, Rockville, MD, 20850, USA., Carvalho AL; Molecular Oncology Research Center, Barretos Cancer Hospital, Rua Antenor Duarte Villela, 1331, Barretos, SP, 784-400, Brazil.; Head and Neck Surgery Department, Barretos Cancer Hospital, Pio XII, 1331, Antenor Duarte Villela St, Barretos, SP, 14784-400, Brazil., Chan AT; Division of Gastroenterology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA, 02115, USA., Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.; Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany., Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, 9609 Medical Center Dr, Rockville, MD, 20850, USA., Chen C; Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, Seattle, WA, 98109, USA., Christiani DC; Department of Epidemiology, Harvard T.H. Chan School of Public Health, 677 Huntington Ave, Boston, MA, 02115, USA., Claes KBM; Centre for Medical Genetics, Ghent University, De Pintelaan 185, 9000, Gent, Belgium., Claessens F; Molecular Endocrinology Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, 3000, Belgium., Clements J; Australian Prostate Cancer Research Centre-Qld, Translational Research Institute, 37 Kent St, Woolloongabba, QLD, 4102, Australia.; Institute of Health and Biomedical Innovation and School of Biomedical Science, Queensland University of Technology, 60 Musk Ave, Kelvin Grove, QLD, 4059, Australia., Collée JM; Department of Clinical Genetics, Erasmus University Medical Center, Wytemaweg 80, 3015, Rotterdam, CN, The Netherlands., Correa MC; University of Puerto Rico Medical Sciences Campus and Comprehensive Cancer Center, San Juan, PR, 00936, USA., Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First StSW, Rochester, MN, 55905, USA., Cox A; Sheffield Institute for Nucleic Acids (SInFoNiA), Department of Oncology and Metabolism, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK., Cunningham JM; Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First StSW, Rochester, MN, 55905, USA., Cybulski C; International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, ulUnii Lubelskiej 1, 71-252, Szczecin, Poland., Czene K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Karolinska Univ Hospital, 171 76, Stockholm, Sweden., Daly MB; Department of Clinical Genetics, Fox Chase Cancer Center, 333 Cottman Ave, Philadelphia, PA, 19111, USA., deFazio A; Centre for Cancer Research, The Westmead Institute for Medical Research, The University of Sydney, 176 Hawkesbury Rd, Sydney, NSW, 2145, Australia.; Department of Gynaecological Oncology, Westmead Hospital, Hawkesbury Rd & Darcy Rd, Sydney, NSW, 2145, Australia., Devilee P; Department of Pathology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.; Department of Human Genetics, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands., Diez O; Oncogenetics Group, Clinical and Molecular Genetics Area, Vall d'Hebron Institute of Oncology (VHIO), University Hospital, Vall d'Hebron, Passeig de la Vall d'Hebron 119-129, 08035, Barcelona, Spain., Gago-Dominguez M; Genomic Medicine Group, Galician Foundation of Genomic Medicine, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, SERGAS, Travesía da Choupana S/N, 15706, Santiago de Compostela, Spain.; Moores Cancer Center, University of California, San Diego, 3855 Health Sciences Drive, La Jolla, CA, 92037, USA., Donovan JL; School of Social and Community Medicine, University of Bristol, Bristol, BS8 1TH, UK., Dörk T; Gynaecology Research Unit, Hannover Medical School, Carl-Neuberg-Straße 1, 30625, Hannover, Germany., Duell EJ; Unit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO-IDIBELL), AvGran Via 199-203, L'Hospitalet de Llobregat, 08908, Barcelona, Spain., Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, 2 Worts' Causeway, Cambridge, CB1 8RN, UK., Dwek M; Department of Biomedical Sciences, Faculty of Science and Technology, University of Westminster, 309 Regent Street, London, W1B 2HW, UK., Eccles DM; Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Tremona Road, Southampton, SO16 6YD, UK., Edlund CK; Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA., Edwards DRV; Vanderbilt Epidemiology Center, Vanderbilt Genetics Institute, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, 2525 West End Avenue, Suite 600, Nashville, TN, 37203, USA., Ellberg C; Department of Cancer Epidemiology, Clinical Sciences, Lund University, Barngatan 4, Skånes universitetssjukhus, 222 42, Lund, Sweden., Evans DG; Manchester Centre for Genomic Medicine, Division of Evolution and Genomic Sciences, University of Manchester, St Mary's Hospital, Central Manchester University Hospitals NHS Foundation Trust, Oxford Road, Manchester, M13 9WL, UK., Fasching PA; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen Nuremberg, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Universitaetsstrasse 21-23, 91054, Erlangen, Germany.; David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles, 10833 Le Conte Ave, Los Angeles, CA, 90095, USA., Ferris RL; Department of Otolaryngology, UPMC Hillman Cancer Center, Cancer Pavilion, University of Pittsburgh, Suite 500, 5150 Centre Avenue, Pittsburgh, PA, 15232, USA., Liloglou T; Molecular and Clinical Cancer Medicine, Roy Castle Lung Cancer Research Programme, The University of Liverpool Institute of Translational Medicine, The Wiliam Duncan Building, 6 West Derby Street, Liverpool, L69 3BX, UK., Figueiredo JC; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA, 90048, USA.; Keck School of Medicine, University of Southern California, 1450 Biggy Street, Los Angeles, CA, 90033, USA., Fletcher O; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, 123 Old Brompton Road, London, SW7 3RP, UK., Fortner RT; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany., Fostira F; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Neapoleos 10, AgParaskevi, Athens, 15310, Greece., Franceschi S; Section of Infections, International Agency for Research on Cancer, 150 cours Albert Thomas, 69008, Lyon, France., Friedman E; The Susanne Levy Gertner Oncogenetics Unit, Chaim Sheba Medical Center, Emek HaEla St 1, 52621, Ramat Gan, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Haim Levanon 30, 69978, Ramat Aviv, Israel., Gallinger SJ; Department of Surgery, Mount Sinai Hospital, 600 University Avenue, Toronto, ON, M5G 1X5, Canada.; Samuel Lunenfeld Research Institute, 600 University Avenue, Toronto, ON, M5G 1X5, Canada.; University Health Network Toronto General Hospital, 200 Elizabeth St, Toronto, ON, M5G 2C4, Canada., Ganz PA; Schools of Medicine and Public Health, Division of Cancer Prevention & Control Research, Jonsson Comprehensive Cancer Centre, UCLA, 650 Charles Young Drive South, Los Angeles, CA, 90095-6900, USA., Garber J; Cancer Risk and Prevention Clinic, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, 02215, USA., García-Sáenz JA; Medical Oncology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Centro Investigación Biomédica en Red de Cáncer (CIBERONC), Calle del Prof Martín Lagos, 28040, Madrid, Spain., Gayther SA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1975 Zonal Ave, Los Angeles, CA, 90033, USA.; Center for Cancer Prevention and Translational Genomics, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Spielberg Building, 8725 Alden Dr, Los Angeles, CA, 90048, USA.; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Spielberg Building, 8725 Alden Dr, Los Angeles, CA, 90048, USA., Giles GG; Cancer Epidemiology & Intelligence Division, Cancer Council Victoria, 615 St Kilda Road, Melbourne, VIC, 3004, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Level 1, 723 Swanston Street, Melbourne, VIC, 3010, Australia.; Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, VIC, Australia., Godwin AK; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS, 66160, USA., Goldberg MS; Department of Medicine, McGill University, 1001 Decarie Boulevard, Montréal, QC, H4A3J1, Canada.; Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University, 1001 Decarie Boulevard, Montréal, QC, H4A3J1, Canada., Goldgar DE; Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, 2000 Circle of Hope, Salt Lake City, UT, 84112, USA., Goode EL; Department of Health Sciences Research, Mayo Clinic, 200 First StSW, Rochester, MN, 55905, USA., Goodman MT; Cancer Prevention and Control, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, 8700 Beverly Blvd, Room 1S37, Los Angeles, CA, 90048, USA.; Community and Population Health Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, 8700 Beverly Blvd, Room 1S37, Los Angeles, CA, 90048, USA., Goodman G; Public Health Sciences Division, Swedish Cancer Institute, 1221 Madison StSte 300, Seattle, WA, 98109, USA., Grankvist K; Unit of Clinical Chemistry, Department of Medical Biosciences, Umeå University, By 6M van 2, Sjukhusomradet, Umea universitet, 901 85, Umea, Sweden., Greene MH; Clinical Genetics Branch, National Cancer Institute, DCEG, 9609 Medical Center Dr, Bethesda, MD, 20850-9772, USA., Gronberg H; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Karolinska Univ Hospital, 171 76, Stockholm, Sweden., Gronwald J; International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, ulUnii Lubelskiej 1, 71-252, Szczecin, Poland., Guénel P; Cancer & Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University Paris-Saclay, 94805, Villejuif, France., Håkansson N; Department of Environmental Medicine, Division of Nutritional Epidemiology, Karolinska Institutet, Nobels väg 13, SE-171 77, SE-171, Stockholm, Sweden., Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Karolinska Univ Hospital, 171 76, Stockholm, Sweden.; Department of Oncology, Södersjukhuset, Sjukhusbacken 10, 118 83, Stockholm, Sweden., Hamann U; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany., Hamdy FC; Nuffield Department of Surgical Sciences, Faculty of Medical Science, John Radcliffe Hospital, University of Oxford, Oxford, OX1 2JD, UK., Hamilton RJ; Department of Surgical Oncology, Princess Margaret Cancer Centre, 610 University Avenue, Toronto, Ontario, M5G2M9, Canada., Hampe J; Department of Internal Medicine 1, University Hospital Dresden, Technische Universität Dresden (TU Dresden), 01307, Dresden, Germany., Haugen A; National Institute of Occupational Health (STAMI), Gydas vei 8, 0033, Oslo, Norway., Heitz F; Department of Gynecology and Gynecologic Oncology, DrHorst Schmidt Kliniken Wiesbaden, Ludwig-Erhard-Straße 100, 65199, Wiesbaden, Germany.; Department of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte/EvangHuyssens-Stiftung/Knappschaft GmbH, Henricistrasse 92, 45136, Essen, Germany., Herrero R; Early Detection and Prevention Section, International Agency for Research on Cancer, 150 cours Albert Thomas, 69008, Lyon, France., Hillemanns P; Gynaecology Research Unit, Hannover Medical School, Carl-Neuberg-Straße 1, 30625, Hannover, Germany., Hoffmeister M; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany., Høgdall E; Department of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100, Copenhagen, Denmark.; Molecular Unit, Department of Pathology, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, DK-2730, Herlev, Denmark., Hong YC; Preventive Medicine, Seoul National University College of Medicine, 1 Gwanak-ro, Gwanak-gu, Seoul, 151 742, Korea., Hopper JL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Level 1, 723 Swanston Street, Melbourne, VIC, 3010, Australia., Houlston R; German Research Center for Environmental Health, Institute for Cancer Research, Ingolstadter Landstr1, London, SM2 5NG, UK., Hulick PJ; Center for Medical Genetics, NorthShore University HealthSystem, 1000 Central St, Evanston, IL, 60201, USA.; The University of Chicago Pritzker School of Medicine, 924 E 57th St, Chicago, IL, 60637, USA., Hunter DJ; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, 677 Huntington Ave, Boston, MA, 02115, USA., Huntsman DG; British Columbia's Ovarian Cancer Research (OVCARE) Program, Vancouver General Hospital, BC Cancer Agency and University of British Columbia, #3427-600 West 10th Avenue, Vancouver, BC, V5Z 4E6, Canada.; Department of Molecular Oncology, BC Cancer Agency Research Centre, #3427-600 West 10th Avenue, Vancouver, BC, V5Z 4E6, Canada.; Department of Pathology and Laboratory Medicine, University of British Columbia, #3427-600 West 10th Avenue, Vancouver, BC, V5Z 4E6, Canada., Idos G; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, 48109, USA., Imyanitov EN; NNPetrov Institute of Oncology, Leningradskaya ul, 68, StPetersburg, Russia, 197758., Ingles SA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, 48109, USA., Isaacs C; Lombardi Comprehensive Cancer Center, Georgetown University, 3800 Reservoir Road, Washington, DC, 20007, USA., Jakubowska A; International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, ulUnii Lubelskiej 1, 71-252, Szczecin, Poland.; Independent Laboratory of Molecular Biology and Genetic Diagnostics, Pomeranian Medical University, Rybacka 1, 70-204, Szczecin, Poland., James P; Sir Peter MacCallum Department of Oncology, The University of Melbourne, 305 Grattan Street, Melbourne, VIC, 3000, Australia.; Parkville Familial Cancer Centre, Peter MacCallum Cancer Center, 305 Grattan Street, Melbourne, VIC, 3000, Australia., Jenkins MA; University of Melbourne Centre for Cancer Research, Victorian Comprehensive Cancer Centre, Parkville, VIC, 3010, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Level 1, 723 Swanston Street, Melbourne, VIC, 3010, Australia., Johansson M; Section of Genetics, International Agency for Research on Cancer, 150 cours Albert Thomas, 69008, Lyon, France., Johansson M; Department of Radiation Sciences, Umeå University, By 6M van 2, Sjukhusomradet, Umea universitet, 901 85, Umea, Sweden., John EM; Department of Medicine, Division of Oncology and Stanford Cancer Institute, Stanford University School of Medicine, 780 Welch Rd, Stanford, CA, 94304, USA., Joshi AD; Department of Epidemiology, Harvard T.H. Chan School of Public Health, 677 Huntington Ave, Boston, MA, 02115, USA.; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, 02114, Boston, MA, USA., Kaneva R; Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, Medical Faculty, Medical University of Sofia, Sofia, 1504, Bulgaria., Karlan BY; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA, 90048, USA., Kelemen LE; Hollings Cancer Center and Department of Public Health Sciences, Medical University of South Carolina, 68 President Street Bioengineering Building, MSC955, Charleston, SC, 29425, USA., Kühl T; Cancer Epidemiology, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany., Khaw KT; Clinical Gerontology, Department of Public Health and Primary Care, University of Cambridge, 2 Worts' Causeway, Cambridge, CB1 8RN, UK., Khusnutdinova E; Department of Genetics and Fundamental Medicine, Bashkir State University, ulZaki Validi 32, Ufa, Russia, 450076.; Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, 71 prosp Oktyabrya, Ufa, Russia, 450054., Kibel AS; Division of Urologic Surgery, Brigham and Womens Hospital, Boston, Massachusettes, 02115, USA., Kiemeney LA; Radboud Institute for Health Sciences, Radboud University Medical Center, Geert Grooteplein 21, 6525 EZ, Nijmegen, The Netherlands., Kim J; Department of Genitourinary Medical Oncology, University of Texas MD Anderson Cancer Center, 1155 Pressler St, Houston, TX, 77030, USA., Kjaer SK; Department of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100, Copenhagen, Denmark.; Department of Gynaecology, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, DK-2100, Copenhagen, Denmark., Knight JA; Prosserman Centre for Population Health Research, Lunenfeld-Tanenbaum Research Institute, Sinai Health System, 60 Murray Street, Toronto, Ontario, M5T 3L9, Canada.; Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, 155 College Street, Toronto, ON, M5T3M7, Canada., Kogevinas M; Biomedical Network on Rare Diseases (CIBERER), AvMonforte de Lemos, 3-5Pabellón 11Planta 0, 28029, Madrid, Spain.; Centre for Research in Environmental Epidemiology (CREAL), ISGlobal, 08036, Barcelona, Spain.; IMIM (Hospital del Mar Research Institute), Barcelona, 08003, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, 08002, Spain., Kote-Jarai Z; Division of Genetics and Epidemiology, The Institute of Cancer Research, 15 Cotswold Road, London, SM2 5NG, UK., Koutros S; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, National Institutes of Health, 9609 Medical Center Dr, Bethesda, MD, 20892, USA., Kristensen VN; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Ullernchausseen 70, 0379, Oslo, Norway.; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Kirkeveien 166, 0450, Oslo, Norway.; Department of Clinical Molecular Biology, Oslo University Hospital, University of Oslo, Kirkeveien 166, 0450, Oslo, Norway., Kupryjanczyk J; Department of Pathology and Laboratory Diagnostics, the Maria Sklodowska-Curie Institute - Oncology Center, Roentgena 5, 02-781, Warsaw, Poland., Lacko M; Head and Neck Surgery, Department of Otorhinolaryngology, Maastricht University Medical Center, PDebyelaan 25, POBox 5800, 6202 AZ, Maastricht, The Netherlands., Lam S; Department of Integrative Oncology, British Columbia Cancer Agency, Room 10-111 675 West 10th Avenue, Vancouver, BC, V5Z1L3, Canada., Lambrechts D; VIB Center for Cancer Biology, VIB, Herestraat 49, 3001, Leuven, Belgium.; Laboratory for Translational Genetics, Department of Human Genetics, University of Leuven, Oude Markt 13, 3000, Leuven, Belgium., Landi MT; Integrative Tumor Epidemiology Branch, DCEG, National Cancer Institute, 9609 Medical Center Drive, Room SG/7E106, Rockville, MD, 20850, USA., Lazarus P; College of Pharmacy, Washington State University, PBS 431 PO Box 1495, Spokane, WA, 99210-1495, USA., Le ND; Cancer Control Research, BC Cancer Agency, 675 West 10th Avenue, Vancouver, BC, V5Z 1L3, Canada., Lee E; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1975 Zonal Ave, Los Angeles, CA, 90033, USA., Lejbkowicz F; Clalit Health Services, Clalit National Israeli Cancer Control Center, Carmel Medical Center, 2 Horev Street, 3436212, Haifa, Israel., Lenz HJ; Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA., Leslie G; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, 2 Worts' Causeway, Cambridge, CB1 8RN, UK., Lessel D; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany., Lester J; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA, 90048, USA., Levine DA; Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.; Gynecologic Oncology, Laura and Isaac Pearlmutter Cancer Center, NYU Langone Medical Center, 240 East 38th Street 19th Floor, New York, NY, 10016, USA., Li L; Department of Family Medicine and Community Health, Mary Ann Swetland Center for Environmental Health, Case Western Reserve University, Cleveland, OH, 44106, USA.; Servicio Galego de Saude (SERGAS), Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), 15706, Santiago De Compostela, Spain., Li CI; Translational Research Program, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Lindblom A; Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska Univ Hospital, 171 76, Stockholm, Sweden., Lindor NM; Health Sciences Research, Mayo Clinic Arizona, 13400 EShea Blvd, Scottsdale, AZ, 85259, USA., Liu G; Epidemiology Division, Princess Margaret Cancer Centre, 610 University Avenue, Toronto, ON, M5G2M9, Canada., Loupakis F; Unit of Oncology 1, Department of Clinical and Experimental Oncology, Istituto Oncologico Veneto IRCCS, 35122, Padua, Italy., Lubiński J; International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, ulUnii Lubelskiej 1, 71-252, Szczecin, Poland., Maehle L; Department of Medical Genetics, Oslo University Hospital, Kirkeveien 166, 0450, Oslo, Norway., Maier C; Institute of Human Genetics, University Hospital Ulm, Prittwitzstrasse 43, 89075, Ulm, Germany., Mannermaa A; Translational Cancer Research Area, University of Eastern Finland, Yliopistonranta 1, 70210, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Yliopistonranta 1, 70210, Finland.; Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Puijonlaaksontie 2, 70210, Kuopio, Finland., Marchand LL; Epidemiology Program, University of Hawaii Cancer Center, 701 Ilalo St, Honolulu, HI, 96813, USA., Margolin S; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, 17177, Sweden., May T; Division of Gynecologic Oncology, University Health Network, Princess Margaret Hospital, 610 University Avenue, OPG Wing, 6-811, Toronto, ON, M5G 2M9, Canada., McGuffog L; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, 2 Worts' Causeway, Cambridge, CB1 8RN, UK., Meindl A; Division of Gynaecology and Obstetrics, , Technische Universität München, Arcisstraße 21, 80333, Munich, Germany., Middha P; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.; Faculty of Medicine, University of Heidelberg, In Neuenheimer Feld 672, 69120, Heidelberg, Germany., Miller A; NRG Oncology, Statistics and Data Management Center, Roswell Park Cancer Institute, Elm & Carlton Streets, Buffalo, NY, 14263, USA., Milne RL; Cancer Epidemiology & Intelligence Division, Cancer Council Victoria, 615 St Kilda Road, Melbourne, VIC, 3004, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Level 1, 723 Swanston Street, Melbourne, VIC, 3010, Australia., MacInnis RJ; Cancer Epidemiology & Intelligence Division, Cancer Council Victoria, 615 St Kilda Road, Melbourne, VIC, 3004, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Level 1, 723 Swanston Street, Melbourne, VIC, 3010, Australia., Modugno F; Womens Cancer Research Center, Magee-Womens Research Institute and Hillman Cancer Center, Pittsburgh, PA, 15213, USA.; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, 300 Halket Street, Pittsburgh, PA, 15213, USA., Montagna M; Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV - IRCCS, Via Gattamelata 64, Padua, 35128, Italy., Moreno V; Catalan Institute of Oncology, Bellvitge Biomedical Research Institute (IDIBELL), Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP) and University of Barcelona, Barcelona, 08908, Spain., Moysich KB; Division of Cancer Prevention and Control, Roswell Park Cancer Institute, Elm & Carlton Streets, Buffalo, NY, 14263, USA., Mucci L; Department of Epidemiology, Harvard T.H. Chan School of Public Health, 677 Huntington Ave, Boston, MA, 02115, USA., Muir K; Division of Population Health, Health Services Research and Primary Care, University of Manchester, Oxford Road, Manchester, M13 9PL, UK.; Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, CV4 7AL, UK., Mulligan AM; Department of Laboratory Medicine and Pathobiology, University of Toronto, 1 King's College Circle, Toronto, ON, M5S1A8, Canada.; Laboratory Medicine Program, University Health Network, 200 Elizabeth Street, Toronto, ON, M5G2C4, Canada., Nathanson KL; Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA, 19104, USA., Neal DE; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, CB2 0RE, Cambridge, UK.; Nuffield Department of Surgical Sciences, Faculty of Medical Science, John Radcliffe Hospital, University of Oxford, Oxford, OX1 2JD, UK.; Department of Oncology, Addenbrooke's Hospital, University of Cambridge, Cambridge, CB1 8RN, UK., Ness AR; NIHR Bristol Biomedical Research Centre Nutrition Theme, University of Bristol, Upper Maudlin Street, Bristol, BS2 8AE, UK., Neuhausen SL; Department of Population Sciences, Beckman Research Institute of City of Hope, 1500 E Duarte, Duarte, CA, 91010, USA., Nevanlinna H; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Haartmaninkatu 8, 00290, Helsinki, Finland., Newcomb PA; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA, 98109-1024, USA.; School of Public Health, University of Washington, 1959 NE Pacific Street, Health Science Buidling, F-350, Seattle, WA, 98195, USA., Newcomb LF; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA, 98109-1024, USA.; Department of Urology, University of Washington, Seattle, Washington, 98195, USA., Nielsen FC; Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, DK-2100, Copenhagen, Denmark., Nikitina-Zake L; Latvian Biomedical Research and Study Centre, Ratsupites str 1, Riga, LV-1067, Latvia., Nordestgaard BG; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev Ringvej 75, 2730, Herlev, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev Ringvej 75, 2730, Herlev, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark., Nussbaum RL; Cancer Genetics and Prevention Program, University of California San Francisco, 1600 Divisadero St, San Francisco, CA, 94143-1714, USA., Offit K; Clinical Genetics Research Lab, Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.; Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA., Olah E; Department of Molecular Genetics, National Institute of Oncology, Ráth György u7-9, 1122, Budapest, Hungary., Olama AAA; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, 2 Worts' Causeway, Cambridge, CB1 8RN, UK.; Department of Clinical Neurosciences, University of Cambridge, Cambridge, CB2 0QQ, UK., Olopade OI; Center for Clinical Cancer Genetics, The University of Chicago, 5841S Maryland Ave, Chicago, IL, 60637, USA., Olshan AF; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, 135 Dauer Dr, Chapel Hill, NC, 27599-7435, USA.; UNC Lineberger Comprehensive Cancer Center, 450 West Dr, Chapell Hill, NC, 27599, USA., Olsson H; Department of Cancer Epidemiology, Clinical Sciences, Lund University, Barngatan 4, Skånes universitetssjukhus, 222 42, Lund, Sweden., Osorio A; Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Calle de Melchor Fernández Almagro, 3, 28029, Madrid, Spain.; Biomedical Network on Rare Diseases (CIBERER), AvMonforte de Lemos, 3-5Pabellón 11Planta 0, 28029, Madrid, Spain., Pandha H; The University of Surrey, Guildford, Surrey, GU2 7XH, UK., Park JY; Department of Cancer Epidemiology, HLee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL, 33612, USA., Pashayan N; Department of Applied Health Research, University College London, 1-19 Torrington Place, London, WC1E 6BT, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, Strangeways Laboratory, University of Cambridge, Cambridge, CB1 8RN, UK., Parsons MT; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, QLD, 4006, Australia., Pejovic T; Department of Obstetrics and Gynecology, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, L-466, Portland, OR, 97239, USA.; Knight Cancer Institute, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, L-466, Portland, OR, 97239, USA., Penney KL; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA, 02115, USA., Peters WHM; Department of Gastroenterology, Radboud University Nijmegen Medical Center, Geert Grooteplein Zuid 10, Internal BOBox 433, 6525 GA, Nijmegen, The Netherlands., Phelan CM; Department of Cancer Epidemiology, HLee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL, 33612, USA., Phipps AI; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA, 98109-1024, USA.; Department of Epidemiology, University of Washington School of Public Health, 1959 NE Pacific St, Seattle, WA, 98195, USA., Plaseska-Karanfilska D; Research Centre for Genetic Engineering and Biotechnology 'Georgi DEfremov', Macedonian Academy of Sciences and Arts, Boulevard Krste Petkov Misirkov, 1000, Skopje, Republic of Macedonia., Pring M; Bristol Dental School, University of Bristol, Lower Maudlin Street, Bristol, BS1 2LY, UK., Prokofyeva D; Department of Genetics and Fundamental Medicine, Bashkir State University, ulZaki Validi 32, Ufa, Russia, 450076., Radice P; Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Research, Fondazione IRCCS (Istituto Di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale dei Tumori (INT), Via Giacomo Venezian 1, 20133, Milan, Italy., Stefansson K; Decode genetics, Sturlugata 8, IS-101 Reykjavik, Reykjavik, Iceland, Iceland., Ramus SJ; School of Women's and Children's Health, Faculty of Medicine, University of NSW Sydney, 18 High St, Sydney, NSW, 2052, Australia.; The Kinghorn Cancer Centre, Garvan Institute of Medical Research, 384 Victoria Street, Sydney, NSW, 2010, Australia., Raskin L; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, 1161 21st Ave S # D3300, Nashville, TN, 37232, USA., Rennert G; Clalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine, 7 Michal Street, 34362, Haifa, Israel., Rennert HS; Clalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine, 7 Michal Street, 34362, Haifa, Israel., van Rensburg EJ; Department of Genetics, University of Pretoria, Private Bag X323, Arcadia, 0007, South Africa., Riggan MJ; Department of Obstetrics and Gynecology, Duke University Medical Center, 25171 Morris Bldg, Durham, NC, 27710, USA., Risch HA; Department of Chronic Disease Epidemiology, Yale School of Public Health, 60 College St, New Haven, CT, 06510, USA., Risch A; Cancer Center Cluster Salzburg at PLUS, Department of Molecular Biology, University of Salzburg, Billrothstr11, 5020, Salzburg, Austria.; Division of Epigenomics and Cancer Risk Factors, DKFZ - German Cancer Research Center, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.; Member of the German Center for Lung Research (DZL), Translational Lung Research Center Heidelberg (TLRC-H), 69120, Heidelberg, Germany., Roobol MJ; Department of Urology, Erasmus University Medical Center, Wytemaweg 80, 3015 CN, Rotterdam, The Netherlands., Rosenstein BS; Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY, 10029, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY, 10029, USA., Rossing MA; Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, Seattle, WA, 98109, USA.; Department of Epidemiology, University of Washington, M4 C308, 1100 Fairview Ave N, Seattle, WA, 98109, USA., De Ruyck K; Faculty of Medicine and Health Sciences, Basic Medical Sciences, Ghent University, De Pintelaan 185, 9000, Gent, Belgium., Saloustros E; Hereditary Cancer Clinic, University Hospital of Heraklion, Voutes, 711 10, Heraklion, Greece., Sandler DP; Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, 111TWAlexander Drive, Research Triangle Park, NC, 27709, USA., Sawyer EJ; Research Oncology, Guy's Hospital, King's College London, Guy's Hospital Great Maze Pond, London, SE1 9RT, UK., Schabath MB; Department of Cancer Epidemiology, HLee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL, 33612, USA., Schleutker J; Institute of Biomedicine, University of Turku, 20014, Turku, Finland.; Division of Laboratory, Department of Medical Genetics, Turku University Hospital, 20014, Turku, Finland.; Prostate Cancer Research Center, Faculty of Medicine and Life Sciences and BioMediTech Institute, University of Tampere, 33014, Tampere, Finland., Schmidt MK; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.; Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek hospital, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands., Setiawan VW; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1450 Biggy Street, Los Angeles, CA, 90033, USA., Shen H; Department of Epidemiology and Biostatistics, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, 101 Longmian Ave, Jiangning District, 211166, Nanjing, People's Republic of China., Siegel EM; Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Dr. MRC-CANCONT, Tampa, FL, 33612, USA., Sieh W; Department of Genetics and Genomic Sciences, Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, 2nd floor, New York, NY, 10029, USA., Singer CF; Dept of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria., Slattery ML; Department of Internal Medicine, University of Utah Health Sciences Center, 295 Chipeta Way, Salt Lake City, UT, 84132, USA., Sorensen KD; Department of Molecular Medicine, Aarhus University Hospital, DK-8200, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, DK-8200, Aarhus, Denmark., Southey MC; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, 246 Clayton Road, Clayton, VIC, 3168, Australia.; Department of Clinical Pathology, The University of Melbourne, Cnr Grattan Street and Royal Parade, Melbourne, VIC, 3010, Australia., Spurdle AB; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, QLD, 4006, Australia., Stanford JL; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA, 98109-1024, USA.; Department of Epidemiology, University of Washington School of Public Health, 1959 NE Pacific St, Seattle, WA, 98195, USA., Stevens VL; Epidemiology Research Program, American Cancer Society, 250 Williams Street NW, Atlanta, GA, 30303, USA., Stintzing S; Department of Medicine III, University Hospital, LMU Munich, Marchioninistr15, 81377, Munich, Germany., Stone J; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Level 1, 723 Swanston Street, Melbourne, VIC, 3010, Australia.; The Curtin UWA Centre for Genetic Origins of Health and Disease, Curtin University and University of Western Australia, 35 Stirling Hwy, Perth, WA, 6000, Australia., Sundfeldt K; Department of Obstetrics and Gynecology, Sahlgrenska Cancer Center, Inst Clinical Scienses, University of Gothenburg, Blå stråket 6, 41345, Gothenburg, Sweden., Sutphen R; Epidemiology Center, College of Medicine, University of South Florida, 3650 Spectrum Blvd, Suite 100, Tampa, FL, 33612, USA., Swerdlow AJ; Division of Genetics and Epidemiology, The Institute of Cancer Research, 15 Cotswold Road, London, SM2 5NG, UK.; Division of Breast Cancer Research, The Institute of Cancer Research, London, SW7 3RP, UK., Tajara EH; Department of Molecular Biology, School of Medicine of São José do Rio Preto, Av Brig Faria Lima 5416 Vila São Pedro, São José do Rio Preto, SP, 15090-000, Brazil.; Department of Genetics and Evolutive Biology, Institute of Biosciences, University of São Paulo, Rua do Matão, 321, São Paulo, SP, 05508-090, Brazil., Tangen CM; SWOG Statistical Center, Fred Hutchinson Cancer Research Center, Seattle, Washington, 98109, USA., Tardon A; Faculty of Medicine, University of Oviedo and CIBERESP, Campus del Cristo s/n, 33006, Oviedo, Spain., Taylor JA; Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, 111TWAlexander Drive, Research Triangle Park, NC, 27709, USA.; Epigenetic and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, NIH, 111TWAlexander Drive, Research Triangle Park, NC, 27709, USA., Teare MD; Medical Statistics Group, School of Health and Related Research (ScHARR), University of Sheffield, Regent Court, 30 Regent Street, Sheffield, S1 4DA, UK., Teixeira MR; Department of Genetics, Portuguese Oncology Institute, Rua DrAntónio Bernardino de Almeida 62, 4220-072, Porto, Portugal.; Biomedical Sciences Institute (ICBAS), University of Porto, RJorge de Viterbo Ferreira 228, 4050-013, Porto, Portugal., Terry MB; Department of Epidemiology, Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY, 10032, USA., Terry KL; Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital, 221 Longwood Avenue RFB 368, Boston, MA, 02115, USA.; Harvard THChan School of Public Health, 221 Longwood Avenue RFB 368, Boston, MA, 02115, USA., Thibodeau SN; Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First StSW, Rochester, MN, 55905, USA., Thomassen M; Department of Clinical Genetics, Odense University Hospital, Sonder Boulevard 29, 5000, Odence C, Denmark., Bjørge L; Department of Gynecology and Obstetrics, Haukeland University Hospital, 5021, Bergen, Norway.; Centre for Cancer Biomarkers CCBIO, Department of Clinical Science, University of Bergen, 5021, Bergen, Norway., Tischkowitz M; Program in Cancer Genetics, Departments of Human Genetics and Oncology, McGill University, 1001 Decarie Boulevard, Montréal, QC, H4A3J1, Canada.; Department of Medical Genetics, Cambridge University, Hills Road, Cambridge, CB2 0QQ, UK., Toland AE; Department of Cancer Biology and Genetics, The Ohio State University, 460W12th Avenue, Columbus, OH, 43210, USA., Torres D; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany.; Institute of Human Genetics, Pontificia Universidad Javeriana, Carrera 7 No40-90, Bogota, Colombia., Townsend PA; Division of Cancer Sciences, Manchester Cancer Research Centre, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, NIHR Manchester Biomedical Research Centre, Health Innovation Manchester, University of Manchester, Manchester, M20 4GJ, UK., Travis RC; Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK., Tung N; Department of Medical Oncology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA, 02215, USA., Tworoger SS; Department of Epidemiology, Harvard T.H. Chan School of Public Health, 677 Huntington Ave, Boston, MA, 02115, USA.; Department of Cancer Epidemiology, HLee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL, 33612, USA., Ulrich CM; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA, 98109-1024, USA.; Huntsman Cancer Institute and Department of Population Health Sciences, University of Utah, 2000 Circle of Hope, Rm 4125, Salt Lake City, UT, 84112, USA., Usmani N; Department of Oncology, Cross Cancer Institute, University of Alberta, 116 St & 85 Ave, Edmonton, AB T6G 2R3, Canada.; Division of Radiation Oncology, Cross Cancer Institute, University of Alberta, 116 St & 85 Ave, Edmonton, AB T6G 2R3, Canada., Vachon CM; Department of Health Sciences Research, Mayo Clinic, 200 First StSW, Rochester, MN, 55905, USA., Van Nieuwenhuysen E; Division of Gynecologic Oncology, Department of Obstetrics and Gynaecology and Leuven Cancer Institute, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium., Vega A; Biomedical Network on Rare Diseases (CIBERER), AvMonforte de Lemos, 3-5Pabellón 11Planta 0, 28029, Madrid, Spain.; Fundación Pública Galega Medicina Xenómica & Instituto de Investigación Sanitaria de Santiago de Compostela, calle Choupana s/n, 15706, Santiago De Compostela, Spain., Aguado-Barrera ME; Fundación Pública Galega Medicina Xenómica & Instituto de Investigación Sanitaria de Santiago de Compostela, calle Choupana s/n, 15706, Santiago De Compostela, Spain., Wang Q; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, 2 Worts' Causeway, Cambridge, CB1 8RN, UK., Webb PM; Population Health Department, QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, QLD, 4006, Australia., Weinberg CR; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, NIH, 111TWAlexander Drive, Research Triangle Park, NC, 27709, USA., Weinstein S; Division of Cancer Epidemiology and Genetics, National Cancer Institute, 9609 Medical Center Dr, Rockville, MD, 20850, USA., Weissler MC; Department of Otolaryngology/Head and Neck Surgery, University of North Carolina at Chapel Hill, Chapel Hill, 27514, NC, USA., Weitzel JN; City of Hope Clinical Cancer Genomics Community Research Network, 1500 East Duarte Road, Duarte, CA, 91010, USA., West CML; Division of Cancer Sciences, University of Manchester, Manchester Cancer Research Centre, Manchester Academic Health Science Centre,, The Christie Hospital NHS Foundation Trust, Manchester, M13 9PL, UK., White E; Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, Seattle, WA, 98109, USA.; Department of Epidemiology, University of Washington, 1100 Fairview Ave N, Seattle, WA, 98109, USA., Whittemore AS; Department of Health Research and Policy - Epidemiology, Stanford University School of Medicine, 259 Campus Drive, Stanford, CA, 94305, USA.; Department of Biomedical Data Science, Stanford University School of Medicine, 259 Campus Drive, Stanford, CA, 94305, USA., Wichmann HE; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology, Ludwig Maximilians University, Neuherberg D-85764, Munich, 803539, Bavaria, Germany.; Helmholtz Zentrum Munchen, German Research Center for Environmental Health (GmbH), Institute of Epidemiology, Ingolstadter Landstr1, 85764, Neuherberg, Germany.; Institute of Medical Statistics and Epidemiology, Technical University Munich, Munich, 80333, Germany., Wiklund F; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Karolinska Univ Hospital, 171 76, Stockholm, Sweden., Winqvist R; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Aapistie 5A, 90220, Oulu, Finland.; Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre Oulu, Aapistie 5A, 90220, Oulu, Finland., Wolk A; Department of Environmental Medicine, Division of Nutritional Epidemiology, Karolinska Institutet, Nobels väg 13, SE-171 77, SE-171, Stockholm, Sweden.; Department of Surgical Sciences, Uppsala University, 751 85, Uppsala, Sweden., Woll P; Academic Unit of Clinical Oncology, University of Sheffield, Weston Park Hospital, Whitham Road, Sheffield, S10 2SJ, UK., Woods M; 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Publikováno v: Nature communications [Nat Commun] 2019 Sep 23; Vol. 10 (1), pp. 4386. Date of Electronic Publication: 2019 Sep 23.

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.

Autor: Milne RL; Cancer Epidemiology and Intelligence Division, Cancer Council Victoria, Melbourne, Victoria, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Kuchenbaecker KB; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Michailidou K; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Electron Microscopy/Molecular Pathology, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus., Beesley J; Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Kar S; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Lindström S; Department of Epidemiology, University of Washington School of Public Health, Seattle, Washington, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Hui S; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada., Lemaçon A; Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Québec, Canada., Soucy P; Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Québec, Canada., Dennis J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Jiang X; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Rostamianfar A; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada., Finucane H; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.; Department of Mathematics, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., Bolla MK; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., McGuffog L; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Wang Q; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Aalfs CM; Department of Clinical Genetics, Academic Medical Center, Amsterdam, the Netherlands., Adams M; Center for Inherited Disease Research (CIDR), Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Adlard J; Yorkshire Regional Genetics Service, Chapel Allerton Hospital, Leeds, UK., Agata S; Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto (IOV), IRCCS, Padua, Italy., Ahmed S; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Ahsan H; Center for Cancer Epidemiology and Prevention, University of Chicago, Chicago, Illinois, USA., Aittomäki K; Department of Clinical Genetics, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Al-Ejeh F; Personalised Medicine Team, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Allen J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Ambrosone CB; Roswell Park Cancer Institute, Buffalo, New York, USA., Amos CI; Center for Genomic Medicine, Department of Biomedical Data Science, Geisel School of Medicine, Dartmouth College, Lebanon, New Hampshire, USA., Andrulis IL; Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada., Anton-Culver H; Department of Epidemiology, University of California, Irvine, Irvine, California, USA., Antonenkova NN; N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus., Arndt V; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany., Arnold N; Institute of Clinical Molecular Biology / Department of Gynecology and Obstetrics, University Hospital of Schleswig-Holstein, Campus Kiel, Christian-Albrechts University Kiel, Kiel, Germany., Aronson KJ; Department of Public Health Sciences and Cancer Research Institute, Queen's University, Kingston, Ontario, Canada., Auber B; Institute of Human Genetics, Hannover Medical School, Hannover, Germany., Auer PL; Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.; Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA., Ausems MGEM; Department of Medical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands., Azzollini J; Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), Istituto Nazionale dei Tumori (INT), Milan, Italy., Bacot F; McGill University and Génome Québec Innovation Centre, Montréal, Québec, Canada., Balmaña J; Department of Medical Oncology, University Hospital, Vall d'Hebron, Barcelona, Spain., Barile M; Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia, Milan, Italy., Barjhoux L; Bâtiment Cheney D, Centre Léon Bérard, Lyon, France., Barkardottir RB; Laboratory of Cell Biology, Department of Pathology, Landspitali, Reykjavik, Iceland.; BMC (Biomedical Centre), Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Barrdahl M; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Barnes D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Barrowdale D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Baynes C; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Beckmann MW; Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany., Benitez J; Human Genotyping Unit -Centro Nacional de Genotipado (CEGEN), Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.; Human Genetics Group, Human Cancer Genetics Programme, Spanish National Cancer Centre (CNIO), Madrid, Spain.; Spanish Network on Rare Diseases (CIBERER), Madrid, Spain., Bermisheva M; Institute of Biochemistry and Genetics, Ufa Scientific Center of the Russian Academy of Sciences, Ufa, Russian Federation., Bernstein L; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California, USA., Bignon YJ; Université Clermont Auvergne, INSERM, U1240, Imagerie Moléculaire et Stratégies Théranostiques, Centre Jean Perrin, Clermont-Ferrand, France., Blazer KR; Clinical Cancer Genetics, City of Hope, Duarte, California, USA., Blok MJ; Department of Clinical Genetics, Maastricht University Medical Center, Maastricht, the Netherlands., Blomqvist C; Department of Oncology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Blot W; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; International Epidemiology Institute, Rockville, Maryland, USA., Bobolis K; City of Hope Clinical Cancer Genomics Community Research Network, Duarte, California, USA., Boeckx B; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory for Translational Genetics, Department of Oncology, University of Leuven, Leuven, Belgium., Bogdanova NV; N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus.; Department of Radiation Oncology, Hannover Medical School, Hannover, Germany.; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Bojesen A; Department of Clinical Genetics, Vejle Hospital, Vejle, Denmark., Bojesen SE; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bonanni B; Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia, Milan, Italy., Børresen-Dale AL; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway., Bozsik A; Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary., Bradbury AR; Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Brand JS; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Brauch H; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.; University of Tübingen, Tübingen, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany., Bressac-de Paillerets B; Gustave Roussy, Biopathology Department, Villejuif, France., Brewer C; Department of Clinical Genetics, Royal Devon and Exeter Hospital, Exeter, UK., Brinton L; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA., Broberg P; Department of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden., Brooks-Wilson A; Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada.; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, British Columbia, Canada., Brunet J; Genetic Counseling Unit, Hereditary Cancer Program, IDIBGI (Institut d'Investigació Biomèdica de Girona), Catalan Institute of Oncology, Girona, Spain., Brüning T; Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum (IPA), Bochum, Germany., Burwinkel B; Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany.; Molecular Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany., Buys SS; Department of Medicine, Huntsman Cancer Institute, Salt Lake City, Utah, USA., Byun J; Center for Genomic Medicine, Department of Biomedical Data Science, Geisel School of Medicine, Dartmouth College, Lebanon, New Hampshire, USA., Cai Q; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Caldés T; Medical Oncology Department, CIBERONC, Hospital Clínico San Carlos, Madrid, Spain., Caligo MA; Section of Molecular Genetics, Department of Laboratory Medicine, University of Pisa and University Hospital of Pisa, Pisa, Italy., Campbell I; Research Department, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia., Canzian F; Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany., Caron O; Gustave Roussy, Biopathology Department, Villejuif, France., Carracedo A; Genomic Medicine Group, Galician Foundation of Genomic Medicine, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, Servizo Galego de Saúde SERGAS, Santiago de Compostela, Spain.; Centro de Investigación en Red de Enfermedades Raras (CIBERER) and Centro Nacional de Genotipado (CEGEN-PRB2), Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Carter BD; Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA., Castelao JE; Oncology and Genetics Unit, Instituto de Investigación Biomédica (IBI) de Orense-Pontevedra-Vigo, Xerencia de Xestión Integrada de Vigo, Servizo Galego de Saúde SERGAS, Vigo, Spain., Castera L; Centre François Baclesse, Caen, France., Caux-Moncoutier V; Service de Génétique Oncologique and INSERM U830, Institut Curie, Paris, France - Université Paris Descartes, Sorbonne Paris Cité., Chan SB, Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA., Chen X; Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Cheng TD; Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Buffalo, New York, USA., Chiquette J; Unité de Recherche en Santé des Populations, Centre des Maladies du Sein Deschênes-Fabia, Hôpital du Saint-Sacrement, Québec City, Québec, Canada., Christiansen H; Department of Radiation Oncology, Hannover Medical School, Hannover, Germany., Claes KBM; Center for Medical Genetics, Ghent University, Ghent, Belgium., Clarke CL; Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia., Conner T; Huntsman Cancer Institute, Salt Lake City, Utah, USA., Conroy DM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Cook J; Sheffield Clinical Genetics Service, Sheffield Children's Hospital, Sheffield, UK., Cordina-Duverger E; Cancer and Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University Paris-Saclay, Villejuif, France., Cornelissen S; Division of Molecular Pathology, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands., Coupier I; Unité d'Oncogénétique, CHU Arnaud de Villeneuve, Montpellier, France., Cox A; Academic Unit of Molecular Oncology, Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK., Cox DG; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; INSERM U1052, Cancer Research Center of Lyon, Lyon, France., Cross SS; Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, Sheffield, UK., Cuk K; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany., Cunningham JM; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Czene K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Daly MB; Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA., Damiola F; Bâtiment Cheney D, Centre Léon Bérard, Lyon, France., Darabi H; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Davidson R; Department of Clinical Genetics, South Glasgow University Hospitals, Glasgow, UK., De Leeneer K; Center for Medical Genetics, Ghent University, Ghent, Belgium., Devilee P; Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands., Dicks E; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Diez O; Oncogenetics Group, Vall d'Hebron Institute of Oncology (VHIO), Clinical and Molecular Genetics Area, Vall d'Hebron University Hospital, Barcelona, Spain., Ding YC; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California, USA., Ditsch N; Department of Gynecology and Obstetrics, Ludwig Maximilians University of Munich, Munich, Germany., Doheny KF; Center for Inherited Disease Research (CIDR), Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Domchek SM; Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Dorfling CM; Cancer Genetics Laboratory, Department of Genetics, University of Pretoria, Arcadia, South Africa., Dörk T; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Dos-Santos-Silva I; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK., Dubois S; Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Québec, Canada., Dugué PA; Cancer Epidemiology and Intelligence Division, Cancer Council Victoria, Melbourne, Victoria, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Dumont M; Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Québec, Canada., Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Durcan L; Southampton Clinical Trials Unit, Faculty of Medicine, University of Southampton, Southampton, UK.; Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK., Dwek M; Department of Biomedical Sciences, Faculty of Science and Technology, University of Westminster, London, UK., Dworniczak B; Institute of Human Genetics, University of Münster, Münster, Germany., Eccles D; Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK., Eeles R; Oncogenetics Team, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, UK., Ehrencrona H; Department of Clinical Genetics, Lund University Hospital, Lund, Sweden., Eilber U; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Ejlertsen B; Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Ekici AB; Institute of Human Genetics, University Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany., Eliassen AH; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Department of Epidemiology, Harvard T.H. 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Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada., Godwin AK; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA., Goldberg MS; Department of Medicine, McGill University, Montréal, Québec, Canada.; Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University, Montréal, Québec, Canada., Goldgar DE; Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA., González-Neira A; Human Genotyping Unit -Centro Nacional de Genotipado (CEGEN), Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Goodfellow P; Department of Obstetrics and Gynecology, Ohio State University James Comprehensive Cancer Center, Columbus, Ohio, USA., Greene MH; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA., Alnæs GIG; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway., Grip M; Department of Surgery, Oulu University Hospital, University of Oulu, Oulu, Finland., Gronwald J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Grundy A; Centre de Recherche du Centre Hospitalier de Université de Montréal (CHUM), Montréal, Québec, Canada., Gschwantler-Kaulich D; Department of Obstetrics and Gynaecology and Comprehensive Cancer Centre, Medical University of Vienna, Vienna, Austria., Guénel P; Cancer and Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University Paris-Saclay, Villejuif, France., Guo Q; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Haeberle L; Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany., Hahnen E; Center for Familial Breast and Ovarian Cancer, University Hospital of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO), University Hospital of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany., Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Håkansson N; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Hallberg E; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA., Hamann U; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Hamel N; McGill University and Génome Québec Innovation Centre, Montréal, Québec, Canada., Hankinson S; Department of Biostatistics and Epidemiology, University of Massachusetts, Amherst, Amherst, Massachusetts, USA., Hansen TVO; Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Harrington P; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Hart SN; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA., Hartikainen JM; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland.; Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland., Healey CS; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Hein A; Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany., Helbig S; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Henderson A; Institute of Genetic Medicine, Centre for Life, Newcastle-upon-Tyne Hospitals NHS Trust, Newcastle-upon-Tyne, UK., Heyworth J; School of Population Health, University of Western Australia, Perth, Western Australia, Australia., Hicks B; Cancer Genomics Research Laboratory (CGR), Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA., Hillemanns P; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Hodgson S; Medical Genetics Unit, St George's, University of London, London, UK., Hogervorst FB; Family Cancer Clinic, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands., Hollestelle A; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, the Netherlands., Hooning MJ; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, the Netherlands., Hoover B; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA., Hopper JL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Hu C; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Huang G; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Hulick PJ; Center for Medical Genetics, NorthShore University HealthSystem, Evanston, Illinois, USA.; Pritzker School of Medicine, University of Chicago, Evanston, Illinois, USA., Humphreys K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Hunter DJ; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Imyanitov EN; N.N. Petrov Institute of Oncology, St. Petersburg, Russian Federation., Isaacs C; Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA., Iwasaki M; Division of Epidemiology, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan., Izatt L; Clinical Genetics, Guy's and St Thomas' NHS Foundation Trust, London, UK., Jakubowska A; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., James P; Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia.; Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Janavicius R; State Research Institute Centre for Innovative Medicine, Vilnius, Lithuania., Janni W; Department of Gynaecology and Obstetrics, University of Ulm, Ulm, Germany., Jensen UB; Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark., John EM; Department of Epidemiology, Cancer Prevention Institute of California, Fremont, California, USA.; Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California, USA., Johnson N; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Jones K; Cancer Genomics Research Laboratory (CGR), Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA., Jones M; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Jukkola-Vuorinen A; Department of Oncology, Oulu University Hospital, University of Oulu, Oulu, Finland., Kaaks R; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Kabisch M; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Kaczmarek K; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Kang D; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.; Cancer Research Institute, Seoul National University, Seoul, Republic of Korea., Kast K; Department of Gynecology and Obstetrics, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Keeman R; Division of Molecular Pathology, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands., Kerin MJ; School of Medicine, National University of Ireland, Galway, Ireland., Kets CM; Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands., Keupers M; Leuven Multidisciplinary Breast Center, Department of Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium., Khan S; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Khusnutdinova E; Institute of Biochemistry and Genetics, Ufa Scientific Center of the Russian Academy of Sciences, Ufa, Russian Federation.; Department of Genetics and Fundamental Medicine, Bashkir State University, Ufa, Russian Federation., Kiiski JI; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Kim SW; Department of Obstetrics and Gynaecology and Comprehensive Cancer Centre, Medical University of Vienna, Vienna, Austria., Knight JA; Prosserman Centre for Health Research, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada.; Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada., Konstantopoulou I; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Athens, Greece., Kosma VM; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland.; Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland., Kristensen VN; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Department of Clinical Molecular Biology, Oslo University Hospital, University of Oslo, Oslo, Norway., Kruse TA; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark., Kwong A; Hong Kong Hereditary Breast Cancer Family Registry, Hong Kong.; Department of Surgery, University of Hong Kong, Hong Kong.; Department of Surgery, Hong Kong Sanatorium and Hospital, Hong Kong., Lænkholm AV; Department of Pathology, University Hospital of Region Zealand, Division Slagelse, Slagelse, Denmark., Laitman Y; Susanne Levy Gertner Oncogenetics Unit, Institute of Human Genetics, Chaim Sheba Medical Center, Ramat Gan, Israel., Lalloo F; Genetic Medicine, Manchester Academic Health Sciences Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK., Lambrechts D; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory for Translational Genetics, Department of Oncology, University of Leuven, Leuven, Belgium., Landsman K; Clalit National Cancer Control Center, Haifa, Israel., Lasset C; Unité de Prévention et d'Epidémiologie Génétique, Centre Léon Bérard, Lyon, France., Lazaro C; Molecular Diagnostic Unit, Hereditary Cancer Program, IDIBELL (Bellvitge Biomedical Research Institute), Catalan Institute of Oncology, Barcelona, Spain., Le Marchand L; University of Hawaii Cancer Center, Honolulu, Hawaii, USA., Lecarpentier J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Lee A; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Lee E; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Lee JW; Department of Surgery, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Republic of Korea., Lee MH; Department of Surgery, Soonchunhyang University and Hospital, Seoul, Republic of Korea., Lejbkowicz F; Clalit National Cancer Control Center, Haifa, Israel., Lesueur F; Institut Curie, Paris, France.; PSL Research University, Paris, France.; INSERM U900, Paris, France.; Mines Paris Tech, Fontainebleau, France., Li J; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Lilyquist J; Department of Health Sciences Research, Mayo Clinic, Scottsdale, Arizona, USA., Lincoln A; Clinical Genetics Research Laboratory, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Lindblom A; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden., Lissowska J; Department of Cancer Epidemiology and Prevention, M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland., Lo WY; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.; University of Tübingen, Tübingen, Germany., Loibl S; German Breast Group, Neu Isenburg, Germany., Long J; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Loud JT; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA., Lubinski J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Luccarini C; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Lush M; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., MacInnis RJ; Cancer Epidemiology and Intelligence Division, Cancer Council Victoria, Melbourne, Victoria, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Maishman T; Southampton Clinical Trials Unit, Faculty of Medicine, University of Southampton, Southampton, UK.; Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK., Makalic E; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Kostovska IM; Research Centre for Genetic Engineering and Biotechnology 'Georgi D. Efremov', Macedonian Academy of Sciences and Arts, Skopje, Macedonia., Malone KE; Division of Public Health Sciences, Epidemiology Program, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Manoukian S; Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), Istituto Nazionale dei Tumori (INT), Milan, Italy., Manson JE; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Margolin S; Department of Oncology, Pathology, Karolinska Institutet, Stockholm, Sweden., Martens JWM; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, the Netherlands., Martinez ME; Moores Cancer Center, University of California, San Diego, La Jolla, California, USA.; Department of Family Medicine and Public Health, University of California, San Diego, La Jolla, California, USA., Matsuo K; Division of Molecular and Clinical Epidemiology, Aichi Cancer Center Research Institute, Nagoya, Japan.; Department of Epidemiology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Mavroudis D; Department of Medical Oncology, University Hospital of Heraklion, Heraklion, Greece., Mazoyer S; Lyon Neuroscience Research Center-CRNL, INSERM U1028, CNRS UMR 5292, University of Lyon, Lyon, France., McLean C; Anatomical Pathology, Alfred Hospital, Melbourne, Victoria, Australia., Meijers-Heijboer H; Department of Clinical Genetics, Academic Medical Center, Amsterdam, the Netherlands.; Department of Clinical Genetics, VU University Medical Centre, Amsterdam, the Netherlands., Menéndez P; Servicio de Anatomía Patológica, Hospital Monte Naranco, Oviedo, Spain., Meyer J; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Miao H; Saw Swee Hock School of Public Health, National University of Singapore, Singapore., Miller A; NRG Oncology, Statistics and Data Management Center, Roswell Park Cancer Institute, Buffalo, New York, USA., Miller N; School of Medicine, National University of Ireland, Galway, Ireland., Mitchell G; Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia.; Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Montagna M; Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto (IOV), IRCCS, Padua, Italy., Muir K; Institute of Population Health, University of Manchester, Manchester, UK.; Division of Health Sciences, Warwick Medical School, Warwick University, Coventry, UK., Mulligan AM; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.; Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada., Mulot C; Université Paris Sorbonne Cité, INSERM UMRS 1147, Paris, France., Nadesan S; City of Hope Clinical Cancer Genomics Community Research Network, Duarte, California, USA., Nathanson KL; Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Neuhausen SL; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California, USA., Nevanlinna H; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Nevelsteen I; Leuven Multidisciplinary Breast Center, Department of Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium., Niederacher D; Department of Gynecology and Obstetrics, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Nielsen SF; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Nordestgaard BG; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Norman A; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA., Nussbaum RL; Department of Medicine, University of California, San Francisco,San Francisco, California, USA., Olah E; Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary., Olopade OI; Center for Clinical Cancer Genetics and Global Health, University of Chicago, Chicago, Illinois, USA., Olson JE; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA., Olswold C; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA., Ong KR; West Midlands Regional Genetics Service, Birmingham Women's Hospital Healthcare NHS Trust, Edgbaston, Birmingham, UK., Oosterwijk JC; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Orr N; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Osorio A; Human Genetics Group, Human Cancer Genetics Programme, Spanish National Cancer Centre (CNIO), Madrid, Spain.; Spanish Network on Rare Diseases (CIBERER), Madrid, Spain., Pankratz VS; University of New Mexico Health Sciences Center, University of New Mexico, Albuquerque, New Mexico, USA., Papi L; Unit of Medical Genetics, Department of Biomedical, Experimental and Clinical Sciences, University of Florence, Florence, Italy., Park-Simon TW; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Paulsson-Karlsson Y; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Lloyd R; Curtin UWA Centre for Genetic Origins of Health and Disease, Curtin University and University of Western Australia, Perth, Western Australia, Australia., Pedersen IS; Section of Molecular Diagnostics, Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark., Peissel B; Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), Istituto Nazionale dei Tumori (INT), Milan, Italy., Peixoto A; Department of Genetics, Portuguese Oncology Institute, Porto, Portugal., Perez JIA; Servicio de Cirugía General y Especialidades, Hospital Monte Naranco, Oviedo, Spain., Peterlongo P; IFOM, FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan, Italy., Peto J; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK., Pfeiler G; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Phelan CM; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, USA., Pinchev M; Clalit National Cancer Control Center, Haifa, Israel., Plaseska-Karanfilska D; Research Centre for Genetic Engineering and Biotechnology 'Georgi D. Efremov', Macedonian Academy of Sciences and Arts, Skopje, Macedonia., Poppe B; Center for Medical Genetics, Ghent University, Ghent, Belgium., Porteous ME; South East of Scotland Regional Genetics Service, Western General Hospital, Edinburgh, UK., Prentice R; Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Presneau N; Department of Biomedical Sciences, Faculty of Science and Technology, University of Westminster, London, UK., Prokofieva D; Department of Genetics and Fundamental Medicine, Bashkir State University, Ufa, Russian Federation., Pugh E; Center for Inherited Disease Research (CIDR), Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Pujana MA; ProCURE, Catalan Institute of Oncology, IDIBELL (Bellvitge Biomedical Research Institute), Barcelona, Spain., Pylkäs K; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland.; Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre Oulu, Oulu, Finland., Rack B; Department of Gynecology and Obstetrics, Ludwig Maximilians University of Munich, Munich, Germany.; Department of Gynaecology and Obstetrics, University of Ulm, Ulm, Germany., Radice P; Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), Istituto Nazionale dei Tumori (INT), Milan, Italy., Rahman N; Section of Cancer Genetics, The Institute of Cancer Research, London, UK., Rantala J; Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden., Rappaport-Fuerhauser C; Department of Obstetrics and Gynaecology and Comprehensive Cancer Centre, Medical University of Vienna, Vienna, Austria., Rennert G; Clalit National Cancer Control Center, Haifa, Israel.; Carmel Medical Center and B. Rappaport Faculty of Medicine-Technion, Haifa, Israel., Rennert HS; Clalit National Cancer Control Center, Haifa, Israel.; Carmel Medical Center and B. Rappaport Faculty of Medicine-Technion, Haifa, Israel., Rhenius V; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Rhiem K; Center for Familial Breast and Ovarian Cancer, University Hospital of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO), University Hospital of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany., Richardson A; Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Rodriguez GC; Division of Gynecologic Oncology, NorthShore University HealthSystem, University of Chicago, Evanston, Illinois, USA., Romero A; Medical Oncology Department, CIBERONC, Hospital Clínico San Carlos, Madrid, Spain.; Medical Oncology Department, Hospital Universitario Puerta de Hierro, Madrid, Spain., Romm J; Center for Inherited Disease Research (CIDR), Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Rookus MA; Department of Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands., Rudolph A; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Ruediger T; Institute of Pathology, Staedtisches Klinikum Karlsruhe, Karlsruhe, Germany., Saloustros E; Hereditary Cancer Clinic, University Hospital of Heraklion, Heraklion, Greece., Sanders J; Department of Pathology, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands., Sandler DP; Epidemiology Branch, National Institute of Environmental Health Sciences, US National Institutes of Health, Research Triangle Park, North Carolina, USA., Sangrajrang S; National Cancer Institute, Bangkok, Thailand., Sawyer EJ; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, Ohio, USA., Schmidt DF; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Schoemaker MJ; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Schumacher F; Research Oncology, Guy's Hospital, King's College London, London, UK., Schürmann P; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Schwentner L; Department of Gynaecology and Obstetrics, University of Ulm, Ulm, Germany., Scott C; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA., Scott RJ; Division of Molecular Medicine, Pathology North, John Hunter Hospital, Newcastle, New South Wales, Australia.; Discipline of Medical Genetics, School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle, Callaghan, New South Wales, Australia., Seal S; Section of Cancer Genetics, The Institute of Cancer Research, London, UK., Senter L; Clinical Cancer Genetics Program, Division of Human Genetics, Department of Internal Medicine, Comprehensive Cancer Center, Ohio State University, Columbus, Ohio, USA., Seynaeve C; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, the Netherlands., Shah M; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Sharma P; Department of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA., Shen CY; School of Public Health, China Medical University, Taichung, Taiwan.; Taiwan Biobank, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan., Sheng X; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Shimelis H; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Shrubsole MJ; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Side LE; North East Thames Regional Genetics Service, Great Ormond Street Hospital for Children NHS Trust, London, UK., Singer CF; Department of Obstetrics and Gynaecology and Comprehensive Cancer Centre, Medical University of Vienna, Vienna, Austria., Sohn C; National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany., Southey MC; Department of Pathology, University of Melbourne, Melbourne, Victoria, Australia., Spinelli JJ; Cancer Control Research, BC Cancer Agency, Vancouver, British Columbia, Canada.; School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada., Spurdle AB; Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Stegmaier C; Saarland Cancer Registry, Saarbrücken, Germany., Stoppa-Lyonnet D; Service de Génétique Oncologique and INSERM U830, Institut Curie, Paris, France - Université Paris Descartes, Sorbonne Paris Cité., Sukiennicki G; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Surowy H; Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany.; Molecular Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany., Sutter C; Institute of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany., Swerdlow A; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.; Division of Breast Cancer Research, The Institute of Cancer Research, London, UK., Szabo CI; National Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA., Tamimi RM; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Tan YY; Department of Obstetrics and Gynaecology and Comprehensive Cancer Centre, Medical University of Vienna, Vienna, Austria., Taylor JA; Epidemiology Branch, National Institute of Environmental Health Sciences, US National Institutes of Health, Research Triangle Park, North Carolina, USA.; Epigenetic and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, US National Institutes of Health, Research Triangle Park, North Carolina, USA., Tejada MI; Molecular Genetics Laboratory, Clinical Genetics Service, Cruces University Hospital and BioCruces Health Research Institute, Barakaldo, Spain., Tengström M; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.; Cancer Center, Kuopio University Hospital, Kuopio, Finland.; Institute of Clinical Medicine, Oncology, University of Eastern Finland, Kuopio, Finland., Teo SH; Cancer Research Malaysia, Subang Jaya, Malaysia.; Breast Cancer Research Unit, Cancer Research Institute, University Malaya Medical Centre, Kuala Lumpur, Malaysia., Terry MB; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA., Tessier DC; McGill University and Génome Québec Innovation Centre, Montréal, Québec, Canada., Teulé A; Genetic Counseling Unit, Hereditary Cancer Program, IDIBELL (Bellvitge Biomedical Research Institute), Catalan Institute of Oncology, Barcelona, Spain., Thöne K; Department of Cancer Epidemiology, Clinical Cancer Registry, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Thull DL; Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Tibiletti MG; Ospedale di Circolo ASST Settelaghi, Varese, Italy., Tihomirova L; Latvian Biomedical Research and Study Centre, Riga, Latvia., Tischkowitz M; Program in Cancer Genetics, Departments of Human Genetics and Oncology, McGill University, Montréal, Québec, Canada.; Department of Medical Genetics, Addenbrooke's Treatment Centre, Addenbrooke's Hospital, Cambridge, UK., Toland AE; Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, Ohio State University, Columbus, Ohio, USA., Tollenaar RAEM; Department of Surgery, Leiden University Medical Center, Leiden, the Netherlands., Tomlinson I; Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, UK., Tong L; Center for Cancer Epidemiology and Prevention, University of Chicago, Chicago, Illinois, USA., Torres D; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Institute of Human Genetics, Pontificia Universidad Javeriana, Bogotá, Colombia., Tranchant M; Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Québec, Canada., Truong T; Cancer and Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University Paris-Saclay, Villejuif, France., Tucker K; Hereditary Cancer Clinic, Department of Medical Oncology, Prince of Wales Hospital, Randwick, New South Wales, Australia., Tung N; Department of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Tyrer J; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Ulmer HU; Frauenklinik der Stadtklinik Baden Baden, Baden Baden, Germany., Vachon C; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA., van Asperen CJ; Department of Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands., Van Den Berg D; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., van den Ouweland AMW; Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, the Netherlands., van Rensburg EJ; Cancer Genetics Laboratory, Department of Genetics, University of Pretoria, Arcadia, South Africa., Varesco L; Unit of Hereditary Cancer, Department of Epidemiology, Prevention and Special Functions, IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) AOU San Martino, IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy., Varon-Mateeva R; Institute of Human Genetics, Campus Virchov Klinikum, Charite Berlin, Berlin, Germany., Vega A; Fundación Pública Galega de Medicina Xenómica, Servizo Galego de Saúde SERGAS, Instituto de Investigaciones Sanitarias (IDIS), Santiago de Compostela, Spain.; Grupo de Medicina Xenómica, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Viel A; Unit of Functional Onco-genomics and Genetics, CRO Aviano, National Cancer Institute, Aviano, Italy., Vijai J; Clinical Genetics Research Laboratory, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Vincent D; McGill University and Génome Québec Innovation Centre, Montréal, Québec, Canada., Vollenweider J; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Walker L; Oxford Regional Genetics Service, Churchill Hospital, Oxford, UK., Wang Z; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Wang-Gohrke S; Department of Gynaecology and Obstetrics, University of Ulm, Ulm, Germany., Wappenschmidt B; Center for Familial Breast and Ovarian Cancer, University Hospital of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO), University Hospital of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany., Weinberg CR; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, US National Institutes of Health, Research Triangle Park, North Carolina, USA., Weitzel JN; Clinical Cancer Genetics, City of Hope, Duarte, California, USA., Wendt C; Department of Oncology, Pathology, Karolinska Institutet, Stockholm, Sweden., Wesseling J; Division of Molecular Pathology, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.; Department of Pathology, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands., Whittemore AS; Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California, USA.; Department of Biomedical Data Sciences, Stanford University School of Medicine, Stanford, California, USA., Wijnen JT; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands.; Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, the Netherlands., Willett W; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Winqvist R; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland.; Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre Oulu, Oulu, Finland., Wolk A; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Wu AH; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Xia L; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Yang XR; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA., Yannoukakos D; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Athens, Greece., Zaffaroni D; Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), Istituto Nazionale dei Tumori (INT), Milan, Italy., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Zhu B; Cancer Genomics Research Laboratory (CGR), Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA., Ziogas A; Department of Epidemiology, University of California, Irvine, Irvine, California, USA., Ziv E; Department of Medicine, Institute for Human Genetics, UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California, USA., Zorn KK; Ospedale di Circolo ASST Settelaghi, Varese, Italy., Gago-Dominguez M; Genomic Medicine Group, Galician Foundation of Genomic Medicine, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, Servizo Galego de Saúde SERGAS, Santiago de Compostela, Spain.; Moores Cancer Center, University of California, San Diego, La Jolla, California, USA., Mannermaa A; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland.; Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland., Olsson H; Department of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden., Teixeira MR; Department of Genetics, Portuguese Oncology Institute, Porto, Portugal.; Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal., Stone J; Curtin UWA Centre for Genetic Origins of Health and Disease, Curtin University and University of Western Australia, Perth, Western Australia, Australia.; Department of Obstetrics and Gynaecology, University of Melbourne and the Royal Women's Hospital, Melbourne, Victoria, Australia., Offit K; Clinical Genetics Research Laboratory, Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Ottini L; Department of Molecular Medicine, University La Sapienza, Rome, Italy., Park SK; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.; Cancer Research Institute, Seoul National University, Seoul, Republic of Korea., Thomassen M; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark., Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Department of Oncology, South General Hospital, Stockholm, Sweden., Meindl A; Division of Gynaecology and Obstetrics, Technische Universität München, Munich, Germany., Schmutzler RK; Center for Familial Breast and Ovarian Cancer, University Hospital of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany., Droit A; Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Québec, Canada., Bader GD; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada., Pharoah PDP; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Kraft P; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Chenevix-Trench G; Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., García-Closas M; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA., Schmidt MK; Division of Molecular Pathology, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.; Division of Psychosocial Research and Epidemiology, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands., Antoniou AC; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Simard J; Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Québec, Canada.

Publikováno v: Nature genetics [Nat Genet] 2017 Dec; Vol. 49 (12), pp. 1767-1778. Date of Electronic Publication: 2017 Oct 23.

Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers.

Autor: Kuchenbaecker KB; The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., McGuffog L; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Barrowdale D; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Lee A; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Soucy P; Genomics Center, Centre Hospitalier Universitaire de Québec Research Center and Laval University, Quebec City, Quebec, Canada., Dennis J; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Domchek SM; Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA., Robson M; Clinical Genetics, Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Spurdle AB; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia., Ramus SJ; School of Women's and Children's Health, University of New South Wales, Australia; The Kinghorn Cancer Centre, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst NSW 2010, Australia., Mavaddat N; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Terry MB; Department of Epidemiology, Columbia University, New York, NY, USA., Neuhausen SL; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA., Schmutzler RK; Center for Hereditary Breast and Ovarian Cancer and Center for Integrated Oncology, Medical Faculty, University Hospital Cologne, Germany., Simard J; Genomics Center, Centre Hospitalier Universitaire de Québec Research Center and Laval University, Quebec City, Quebec, Canada., Pharoah PDP; Department of Oncology, University of Cambridge, Cambridge, UK., Offit K; Clinical Genetics Research Laboratory, Department of Medicine, Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA., Couch FJ; Department of Laboratory Medicine and Pathology, and Health Sciences Research, Mayo Clinic, Rochester, MN, USA., Chenevix-Trench G; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia., Easton DF; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Antoniou AC; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

Publikováno v: Journal of the National Cancer Institute [J Natl Cancer Inst] 2017 Jul 01; Vol. 109 (7).

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

Autor: Phelan CM; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, USA.; Department of Gynecologic Oncology, Moffitt Cancer Center, Tampa, Florida, USA., Kuchenbaecker KB; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK., Tyrer JP; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK., Kar SP; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK., Lawrenson K; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Winham SJ; Division of Biomedical Statistics and Informatics, Department of Health Science Research, Mayo Clinic, Rochester, Minnesota, USA., Dennis J; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK., Pirie A; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK., Riggan MJ; Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina, USA., Chornokur G; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, USA., Earp MA; Department of Health Science Research, Division of Epidemiology, Mayo Clinic, Rochester, Minnesota, USA., Lyra PC Jr; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, USA., Lee JM; Center for Bioinformatics and Functional Genomics, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Coetzee S; Center for Bioinformatics and Functional Genomics, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Beesley J; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., McGuffog L; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Soucy P; Genomics Center, Centre Hospitalier Universitaire de Québec Research Center and Laval University, Quebec City, Quebec, Canada., Dicks E; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK., Lee A; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Barrowdale D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Lecarpentier J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Leslie G; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Aalfs CM; Department of Clinical Genetics, Academic Medical Center, Amsterdam, the Netherlands., Aben KKH; Radboud University Medical Center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, the Netherlands.; Netherlands Comprehensive Cancer Organisation, Utrecht, the Netherlands., Adams M; Center for Inherited Disease Research, Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Adlard J; Yorkshire Regional Genetics Service, Chapel Allerton Hospital, Leeds, UK., Andrulis IL; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital and Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Anton-Culver H; Genetic Epidemiology Research Institute, UCI Center for Cancer Genetics Research and Prevention, School of Medicine, University of California-Irvine, Irvine, California, USA.; Department of Epidemiology, University of California-Irvine, Irvine, California, USA., Antonenkova N; N.N. Alexandrov National Cancer Centre of Belarus, Minsk, Belarus., Aravantinos G; 'Agii Anargiri' Cancer Hospital, Athens, Greece., Arnold N; Department of Gynaecology and Obstetrics, University Hospital of Schleswig-Holstein, Campus Kiel, Christian Albrechts University Kiel, Kiel, Germany., Arun BK; Department of Breast Medical Oncology and Clinical Cancer Genetics Program, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Arver B; Department of Oncology and Pathology, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden., Azzollini J; Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale Tumori (INT), Milan, Italy., Balmaña J; Department of Medical Oncology, University Hospital, Vall d'Hebron, Barcelona, Spain., Banerjee SN; Gynaecology Unit, Royal Marsden Hospital, London, UK., Barjhoux L; Bâtiment Cheney D, Centre Léon Bérard, Lyon, France., Barkardottir RB; Laboratory of Cell Biology, Department of Pathology, Landspitali, Reykjavik, Iceland.; BMC (Biomedical Centre), Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Bean Y; Department of Gynecologic Oncology, Oregon Health &Science University, Portland, Oregon, USA.; Knight Cancer Institute, Oregon Health &Science University, Portland, Oregon, USA., Beckmann MW; Department of Gynecology and Obstetrics, Universtiy Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-Nuremberg, Erlangen, Germany., Beeghly-Fadiel A; Division of Epidemiology, Department of Medicine, Vanderbilt School of Medicine, Nashville, Tennessee, USA.; Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt Medical School, Nashville, Tennessee, USA.; Institute for Medicine and Public Health, Vanderbilt School of Medicine, Nashville, Tennessee, USA.; Vanderbilt-Ingram Cancer Center, Vanderbilt School of Medicine, Nashville, Tennessee, USA., Benitez J; Human Genetics Group, Spanish National Cancer Centre (CNIO), Madrid, Spain.; Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain., Bermisheva M; Institute of Biochemistry and Genetics, Ufa Science Center, Russian Academy of Sciences, Ufa, Russian Federation., Bernardini MQ; Division of Gynecologic Oncology, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada., Birrer MJ; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA., Bjorge L; Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway.; Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Bergen, Norway., Black A; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA., Blankstein K; Clinical Cancer Genetics for the City of Hope, Clinical Cancer Genetics Community Research Network, Duarte, California, USA., Blok MJ; Department of Clinical Genetics, Maastricht University Medical Center, Maastricht, the Netherlands., Bodelon C; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA., Bogdanova N; Radiation Oncology Research Unit, Hannover Medical School, Hannover, Germany., Bojesen A; Department of Clinical Genetics, Vejle Hospital, Vejle, Denmark., Bonanni B; Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia (IEO), Milan, Italy., Borg Å; Department of Oncology, Clinical Sciences, Lund University and Skåne University Hospital, Lund, Sweden., Bradbury AR; Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Brenton JD; Cancer Research UK (CRUK) Cambridge Institute, University of Cambridge, Cambridge, UK., Brewer C; Department of Clinical Genetics, Royal Devon and Exeter Hospital, Exeter, UK., Brinton L; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA., Broberg P; Department of Cancer Epidemiology, University Hospital, Lund, Lund University, Lund, Sweden., Brooks-Wilson A; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada., Bruinsma F; Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria, Australia., Brunet J; Genetic Counseling Unit, Hereditary Cancer Program, IDIBGI (Institut d'Investigació Biomèdica de Girona), Catalan Institute of Oncology, Girona, Spain., Buecher B; Service de Génétique Oncologique, Institut Curie, Paris, France., Butzow R; Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Buys SS; Department of Medicine, Huntsman Cancer Institute, Salt Lake City, Utah, USA., Caldes T; Molecular Oncology Laboratory, Hospital Clínico San Carlos, IdISSC (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos), Madrid, Spain., Caligo MA; Section of Genetic Oncology, Department of Laboratory Medicine, University and University Hospital of Pisa, Pisa, Italy., Campbell I; Cancer Genetics Laboratory, Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Department of Pathology, University of Melbourne, Parkville, Victoria, Australia., Cannioto R; Cancer Pathology and Prevention, Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Buffalo, New York, USA., Carney ME; Department of Obstetrics and Gynecology, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, USA., Cescon T; Clinical Cancer Genetics for the City of Hope, Clinical Cancer Genetics Community Research Network, Duarte, California, USA., Chan SB; Cancer Risk Program, University of California, San Francisco, San Francisco, California, USA., Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Chanock S; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA., Chen XQ; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Chiew YE; Centre for Cancer Research, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.; Department of Gynaecological Oncology, Westmead Hospital, Sydney, New South Wales, Australia., Chiquette J; Unité de Recherche en Santé des Populations, Centre des Maladies du Sein Deschênes-Fabia, Centre de Recherche FRSQ du Centre Hospitalier Affilié Universitaire de Québec, Quebec City, Quebec, Canada., Chung WK; Departments of Pediatrics and Medicine, Columbia University, New York, New York, USA., Claes KBM; Center for Medical Genetics, Ghent University, Ghent, Belgium., Conner T; Department of Medicine, Huntsman Cancer Institute, Salt Lake City, Utah, USA., Cook LS; Division of Epidemiology, Biostatistics and Preventative Medicine, Department of Internal Medicine, University of New Mexico, Albuquerque, New Mexico, USA., Cook J; Sheffield Clinical Genetics Service, Sheffield Children's Hospital, Sheffield, UK., Cramer DW; Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Cunningham JM; Division of Experimental Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., D'Aloisio AA; Social &Scientific Systems, Inc., Durham, North Carolina, USA., Daly MB; Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA., Damiola F; Bâtiment Cheney D, Centre Léon Bérard, Lyon, France., Damirovna SD; Department of Genetics and Fundamental Medicine, Bashkir State University, Ufa, Russian Federation., Dansonka-Mieszkowska A; Department of Pathology and Laboratory Diagnostics, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland., Dao F; Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Davidson R; Department of Clinical Genetics, South Glasgow University Hospitals, Glasgow, UK., DeFazio A; Centre for Cancer Research, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.; Department of Gynaecological Oncology, Westmead Hospital, Sydney, New South Wales, Australia., Delnatte C; Unité d'Oncogénétique, ICO-Centre René Gauducheau, Nantes, France., Doheny KF; Center for Inherited Disease Research, Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Diez O; Oncogenetics Group, Vall d'Hebron Institute of Oncology, Barcelona, Spain.; Clinical and Molecular Genetics Area, Vall d'Hebron University Hospital. Barcelona, Spain., Ding YC; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California, USA., Doherty JA; Department of Epidemiology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA., Domchek SM; Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Dorfling CM; Cancer Genetics Laboratory, Department of Genetics, University of Pretoria, Pretoria, South Africa., Dörk T; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Dossus L; Nutrition and Metabolism Section, International Agency for Research on Cancer (IARC-WHO), Lyon, France., Duran M; Institute of Biology and Molecular Genetics, Universidad de Valladolid (IBGM-UVA), Valladolid, Spain., Dürst M; Department of Gynecology, Jena University Hospital-Friedrich Schiller University, Jena, Germany., Dworniczak B; Institute of Human Genetics, Münster, Germany., Eccles D; University of Southampton Faculty of Medicine, Southampton University Hospitals NHS Trust, Southampton, UK., Edwards T; Division of Epidemiology, Department of Medicine, Vanderbilt School of Medicine, Nashville, Tennessee, USA.; Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt Medical School, Nashville, Tennessee, USA.; Institute for Medicine and Public Health, Vanderbilt School of Medicine, Nashville, Tennessee, USA.; Vanderbilt-Ingram Cancer Center, Vanderbilt School of Medicine, Nashville, Tennessee, USA., Eeles R; Oncogenetics Team, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, UK., Eilber U; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Ejlertsen B; Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Ekici AB; Institute of Human Genetics, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany., Ellis S; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Elvira M; Department of Genetics and Fundamental Medicine, Bashkir State University, Ufa, Russian Federation., Eng KH; Department of Biostatistics and Bioinformatics, Roswell Park Institute, Buffalo, New York, USA., Engel C; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany., Evans DG; Genomic Medicine, Manchester Academic Health Sciences Centre, University of Manchester, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK., Fasching PA; Department of Gynecology and Obstetrics, Universtiy Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-Nuremberg, Erlangen, Germany.; Division of Hematology and Oncology, Department of Medicine, UCLA David Geffen School of Medicine, Los Angeles, California, USA., Ferguson S; Division of Gynecologic Oncology, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada., Ferrer SF; Laboratoire de Génétique Chromosomique, Hôtel Dieu Centre Hospitalier, Chambéry, France., Flanagan JM; Department of Surgery and Cancer, Imperial College London, London, UK., Fogarty ZC; Division of Biomedical Statistics and Informatics, Department of Health Science Research, Mayo Clinic, Rochester, Minnesota, USA., Fortner RT; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Fostira F; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Aghia Paraskevi Attikis, Athens, Greece., Foulkes WD; Program in Cancer Genetics, Departments of Human Genetics and Oncology, McGill University, Montreal, Quebec, Canada., Fountzilas G; Department of Medical Oncology, Papageorgiou, Hospital, Aristotle University of Thessaloniki School of Medicine, Thessaloniki, Greece., Fridley BL; Biostatistics and Informatics Shared Resource, University of Kansas Medical Center, Kansas City, Kansas, USA., Friebel TM; Harvard T.H. Chan School of Public Health and Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Friedman E; Susanne Levy Gertner Oncogenetics Unit, Institute of Human Genetics, Chaim Sheba Medical Center, Ramat Gan, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel., Frost D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Ganz PA; Division of Cancer Prevention and Control Research, Jonsson Comprehensive Cancer Center, UCLA Schools of Medicine and Public Health, Los Angeles, California, USA., Garber J; Cancer Risk and Prevention Clinic, Dana-Farber Cancer Institute, Boston, Massachusetts, USA., García MJ; Human Genetics Group, Spanish National Cancer Centre (CNIO), Madrid, Spain.; Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain., Garcia-Barberan V; Molecular Oncology Laboratory, Hospital Clínico San Carlos, IdISSC (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos), Madrid, Spain., Gehrig A; Centre of Familial Breast and Ovarian Cancer, Department of Medical Genetics, Institute of Human Genetics, University Würzburg, Würzburg, Germany., Gentry-Maharaj A; Women's Cancer, Institute for Women's Health, University College London, London, UK., Gerdes AM; Department of Clinical Genetics, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Giles GG; Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria, Australia.; Centre for Epidemiology and Biostatistics, School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia.; Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia., Glasspool R; Beatson West of Scotland Cancer Centre, Glasgow, UK., Glendon G; Ontario Cancer Genetics Network: Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada., Godwin AK; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA., Goldgar DE; Department of Dermatology, University of Utah School of Medicine, Salt Lake City, Utah, USA., Goranova T; Cancer Research UK (CRUK) Cambridge Institute, University of Cambridge, Cambridge, UK., Gore M; Department of Medicine, Royal Marsden Hospital, London, UK., Greene MH; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA., Gronwald J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Gruber S; Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA., Hahnen E; Center for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO) and Center for Molecular Medicine Cologne (CMMC), University Hospital Cologne, Cologne, Germany., Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA., Håkansson N; Division of Nutritional Epidemiology, Department of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Hamann U; Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany., Hansen TVO; Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Harrington PA; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK., Harris HR; Division of Nutritional Epidemiology, Department of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Hauke J; Center for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO) and Center for Molecular Medicine Cologne (CMMC), University Hospital Cologne, Cologne, Germany., Hein A; Department of Gynecology and Obstetrics, Universtiy Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-Nuremberg, Erlangen, Germany., Henderson A; Institute of Genetic Medicine, Centre for Life, Newcastle-upon-Tyne Hospitals NHS Trust, Newcastle-upon-Tyne, UK., Hildebrandt MAT; Department of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Hillemanns P; Clinics of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany., Hodgson S; Medical Genetics Unit, St George's University of London, London, UK., Høgdall CK; Department of Gynecology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Høgdall E; Department of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark.; Molecular Unit, Department of Pathology, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark., Hogervorst FBL; Family Cancer Clinic, Netherlands Cancer Institute, Amsterdam, the Netherlands., Holland H; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Hooning MJ; Department of Medical Oncology, Family Cancer Clinic, Erasmus University Medical Center, Rotterdam, the Netherlands., Hosking K; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK., Huang RY; Center for Immunotherapy, Roswell Park Cancer Institute, Buffalo, New York, USA., Hulick PJ; Center for Medical Genetics, NorthShore University HealthSystem, University of Chicago Pritzker School of Medicine, Evanston, Illinois, USA., Hung J; Centre for Cancer Research, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.; Department of Gynaecological Oncology, Westmead Hospital, Sydney, New South Wales, Australia., Hunter DJ; Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Huntsman DG; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; British Columbia Cancer Agency, Vancouver, British Columbia, Canada., Huzarski T; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Imyanitov EN; N.N. Petrov Institute of Oncology, St. Petersburg, Russian Federation., Isaacs C; Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA., Iversen ES; Department of Statistical Science, Duke University, Durham, North Carolina, USA., Izatt L; Clinical Genetics, Guy's and St Thomas' NHS Foundation Trust, London, UK., Izquierdo A; Genetic Counseling Unit, Hereditary Cancer Program, IDIBGI (Institut d'Investigació Biomèdica de Girona), Catalan Institute of Oncology, Girona, Spain., Jakubowska A; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., James P; Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia., Janavicius R; Department of Molecular and Regenerative Medicine, Hematology, Oncology and Transfusion Medicine Center, Vilnius University Hospital Santariskiu Clinics, Vilnius, Lithuania.; State Research Institute Centre for Innovative Medicine, Vilnius, Lithuania., Jernetz M; Department of Obstetrics and Gynecology, Lund University Hospital, Lund, Sweden., Jensen A; Department of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark., Jensen UB; Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark., John EM; Department of Epidemiology, Cancer Prevention Institute of California, Fremont, California, USA., Johnatty S; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Jones ME; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK., Kannisto P; Department of Obstetrics and Gynecology, Lund University Hospital, Lund, Sweden., Karlan BY; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Karnezis A; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; British Columbia Cancer Agency, Vancouver, British Columbia, Canada., Kast K; Department of Gynaecology and Obstetrics, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany., Kennedy CJ; Centre for Cancer Research, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.; Department of Gynaecological Oncology, Westmead Hospital, Sydney, New South Wales, Australia., Khusnutdinova E; Institute of Biochemistry and Genetics, Ufa Science Center, Russian Academy of Sciences, Ufa, Russian Federation., Kiemeney LA; Radboud University Medical Center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, the Netherlands., Kiiski JI; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland., Kim SW; Department of Surgery, Breast Care Center, Daerim St. Mary's Hospital, Seoul, Republic of Korea., Kjaer SK; Department of Gynecology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.; Department of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark., Köbel M; Department of Pathology, University of Calgary, Calgary, Alberta, Canada., Kopperud RK; Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway.; Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Bergen, Norway., Kruse TA; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark., Kupryjanczyk J; Department of Pathology and Laboratory Diagnostics, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland., Kwong A; Hong Kong Hereditary Breast Cancer Family Registry, Hong Kong.; Department of Surgery, University of Hong Kong, Hong Kong.; Cancer Genetics Center and Department of Surgery, Hong Kong Sanatorium and Hospital, Hong Kong., Laitman Y; Susanne Levy Gertner Oncogenetics Unit, Institute of Human Genetics, Chaim Sheba Medical Center, Ramat Gan, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel., Lambrechts D; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory for Translational Genetics, Department of Oncology, KU Leuven, Leuven, Belgium., Larrañaga N; Public Health Division of Gipuzkoa, Regional Government of the Basque Country, Donostia-San Sebastian, Spain.; CIBER of Epidemiology and Public Health, Madrid, Spain., Larson MC; Division of Biomedical Statistics and Informatics, Department of Health Science Research, Mayo Clinic, Rochester, Minnesota, USA., Lazaro C; Molecular Diagnostic Unit, Hereditary Cancer Program, IDIBELL-Catalan Institute of Oncology, Barcelona, Spain., Le ND; Cancer Control Research, BC Cancer Agency, Vancouver, British Columbia, Canada., Le Marchand L; Cancer Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, USA., Lee JW; Department of Surgery, Ulsan College of Medicine and Asan Medical Center, Seoul, Republic of Korea., Lele SB; Department of Gynecological Oncology, Roswell Park Cancer Institute, Buffalo, New York, USA., Leminen A; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland., Leroux D; Département de Génétique, Centre Hospitalier Universitaire de Grenoble, Grenoble, France., Lester J; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Lesueur F; Institut Curie, PSL Research Unviersity and INSERM U900, Paris, France.; Mines Paris Tech, Fontainebleau, France., Levine DA; Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Liang D; College of Pharmacy and Health Sciences, Texas Southern University, Houston, Texas, USA., Liebrich C; Cancer Center Wolfsburg, Clinics of Gynaecology, Wolfsburg, Germany., Lilyquist J; Department of Health Sciences Research, Division of Epidemiology, Mayo Clinic, Rochester, Minnesota, USA., Lipworth L; Division of Epidemiology, Department of Medicine, Vanderbilt School of Medicine, Nashville, Tennessee, USA.; Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt Medical School, Nashville, Tennessee, USA.; Vanderbilt-Ingram Cancer Center, Vanderbilt School of Medicine, Nashville, Tennessee, USA., Lissowska J; Department of Cancer Epidemiology and Prevention, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland., Lu KH; Department of Gynecologic Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Lubinński J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Luccarini C; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK., Lundvall L; Juliane Marie Centre, Department of Gynecology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Mai PL; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA., Mendoza-Fandiño G; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, USA., Manoukian S; Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale Tumori (INT), Milan, Italy., Massuger LFAG; Radboud University Medical Center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, the Netherlands., May T; Division of Gynecologic Oncology, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada., Mazoyer S; INSERM U1052, CNRS UMR 5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Centre Léon Bérard, Lyon, France., McAlpine JN; Ovarian Cancer Research (OVCARE) Program-Gynecologic Tissue Bank, Vancouver General Hospital and BC Cancer Agency, Vancouver, British Columbia, Canada., McGuire V; Department of Health Research and Policy-Epidemiology, Stanford University School of Medicine, Stanford, California, USA., McLaughlin JR; Public Health Ontario, Toronto, Ontario, Canada., McNeish I; Institute of Cancer Sciences, University of Glasgow, Wolfson Wohl Cancer Research Centre, Beatson Institute for Cancer Research, Glasgow, UK., Meijers-Heijboer H; Department of Clinical Genetics, VU University Medical Centre, Amsterdam, the Netherlands., Meindl A; Department of Gynaecology and Obstetrics, Division of Tumor Genetics, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany., Menon U; Women's Cancer, Institute for Women's Health, University College London, London, UK., Mensenkamp AR; Department of Human Genetics, Radboud University Medical Centre, Nijmegen, the Netherlands., Merritt MA; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Milne RL; Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria, Australia.; Centre for Epidemiology and Biostatistics, School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Mitchell G; Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia., Modugno F; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA.; Ovarian Cancer Center of Excellence, Womens Cancer Research Program, Magee-Womens Research Institute and University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA., Moes-Sosnowska J; Department of Pathology and Laboratory Diagnostics, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland., Moffitt M; Knight Cancer Institute, Oregon Health &Science University, Portland, Oregon, USA.; Department of Obstetrics and Gynecology, Oregon Health &Science University, Portland, Oregon, USA., Montagna M; Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy., Moysich KB; Cancer Pathology and Prevention, Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Buffalo, New York, USA., Mulligan AM; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Keenan Research Centre of the Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada., Musinsky J; Clinical Genetics Research Laboratory, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Nathanson KL; Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Nedergaard L; Department of Pathology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Ness RB; University of Texas School of Public Health, Houston, Texas, USA., Neuhausen SL; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California, USA., Nevanlinna H; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland., Niederacher D; Department of Gynaecology and Obstetrics, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Nussbaum RL; Invitae Corporation, San Francisco, California, USA.; Department of Medicine, University of California, San Francisco, San Francisco, California, USA., Odunsi K; Department of Gynecological Oncology, Roswell Park Cancer Institute, Buffalo, New York, USA., Olah E; Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary., Olopade OI; Center for Clinical Cancer Genetics and Global Health, University of Chicago Medical Center, Chicago, Illinois, USA., Olsson H; Department of Cancer Epidemiology, University Hospital, Lund, Lund University, Lund, Sweden.; Department of Oncology, Lund University Hospital, Lund, Sweden., Olswold C; Department of Health Sciences Research, Division of Epidemiology, Mayo Clinic, Rochester, Minnesota, USA., O'Malley DM; Department of Obstetrics and Gynecology, Ohio State University and the James Cancer Center, Columbus, Ohio, USA., Ong KR; West Midlands Regional Genetics Service, Birmingham Women's Hospital Healthcare NHS Trust, Edgbaston, Birmingham, UK., Onland-Moret NC; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands., Orr N; Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London, UK., Orsulic S; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Osorio A; Human Genetics Group, Spanish National Cancer Centre (CNIO), Madrid, Spain., Palli D; Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute-ISPO, Florence, Italy., Papi L; Unit of Medical Genetics, Department of Biomedical, Experimental and Clinical Sciences, University of Florence, Florence, Italy., Park-Simon TW; Clinics of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany., Paul J; Cancer Research UK Clinical Trials Unit, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Pearce CL; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA.; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., Pedersen IS; Section of Molecular Diagnostics, Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark., Peeters PHM; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands., Peissel B; Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale Tumori (INT), Milan, Italy., Peixoto A; Department of Genetics, Portuguese Oncology Institute, Porto, Portugal., Pejovic T; Knight Cancer Institute, Oregon Health &Science University, Portland, Oregon, USA.; Department of Obstetrics and Gynecology, Oregon Health &Science University, Portland, Oregon, USA., Pelttari LM; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland., Permuth JB; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, USA., Peterlongo P; IFOM, FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan, Italy., Pezzani L; Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale Tumori (INT), Milan, Italy., Pfeiler G; Department of Obstetrics and Gynecology, Medical University of Vienna and Comprehensive Cancer Center, Vienna, Austria., Phillips KA; Centre for Epidemiology and Biostatistics, School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia.; Division of Cancer Medicine, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia., Piedmonte M; NRG Oncology, Statistics and Data Management Center, Roswell Park Cancer Institute, Buffalo, New York, USA., Pike MC; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA.; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Piskorz AM; Cancer Research UK (CRUK) Cambridge Institute, University of Cambridge, Cambridge, UK., Poblete SR; Department of Gynecological Oncology, Roswell Park Cancer Institute, Buffalo, New York, USA., Pocza T; Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary., Poole EM; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Poppe B; Center for Medical Genetics, Ghent University, Ghent, Belgium., Porteous ME; South East of Scotland Regional Genetics Service, Western General Hospital, Edinburgh, UK., Prieur F; Service de Génétique Clinique Chromosomique et Moléculaire, Centre Hospitalier Universitaire de St Etienne, St Etienne, France., Prokofyeva D; Department of Genetics and Fundamental Medicine, Bashkir State University, Ufa, Russian Federation., Pugh E; Center for Inherited Disease Research, Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Pujana MA; Translational Research Laboratory, IDIBELL (Bellvitge Biomedical Research Institute), Catalan Institute of Oncology, Barcelona, Spain., Pujol P; Unité d'Oncogénétique, Centre Hospitalier Universitaire Arnaud de Villeneuve, Montpellier, France., Radice P; Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale Tumori (INT), Milan, Italy., Rantala J; Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden., Rappaport-Fuerhauser C; Department of Obstetrics and Gynecology, Medical University of Vienna and Comprehensive Cancer Center, Vienna, Austria., Rennert G; Clalit National Israeli Cancer Control Center, Haifa, Israel.; Department of Community Medicine and Epidemiology, Carmel Medical Center and B. Rappaport Faculty of Medicine, Haifa, Israel., Rhiem K; Center for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO) and Center for Molecular Medicine Cologne (CMMC), University Hospital Cologne, Cologne, Germany., Rice P; Clinical Cancer Genetics for the City of Hope, Clinical Cancer Genetics Community Research Network, Duarte, California, USA., Richardson A; Department of Pathology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Robson M; Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Rodriguez GC; Division of Gynecologic Oncology, NorthShore University HealthSystem, University of Chicago, Evanston, Illinois, USA., Rodríguez-Antona C; Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain.; Hereditary Endocrine Cancer Group, Spanish National Cancer Research Center (CNIO), Madrid, Spain., Romm J; Center for Inherited Disease Research, Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Rookus MA; Department of Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands., Rossing MA; Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Rothstein JH; Department of Health Research and Policy-Epidemiology, Stanford University School of Medicine, Stanford, California, USA., Rudolph A; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Runnebaum IB; Department of Gynecology, Jena University Hospital-Friedrich Schiller University, Jena, Germany., Salvesen HB; Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway.; Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Bergen, Norway., Sandler DP; Epidemiology Branch, Division of Intramural Research, National Institute of Environmental Health Sciences, US National Institutes of Health, Research Triangle Park, North Carolina, USA., Schoemaker MJ; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK., Senter L; Clinical Cancer Genetics Program, Division of Human Genetics, Department of Internal Medicine, Comprehensive Cancer Center, Ohio State University, Columbus, Ohio, USA., Setiawan VW; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA., Severi G; Facultés de Médecin, Université Paris-Sud, Villejuif, France.; Institut Gustave Roussy, Villejuif, France.; Human Genetics Foundation (HuGeF), Turin, Italy.; Facultés de Médecin, Université Paris-Saclay, Paris, France., Sharma P; Department of Hematology and Oncology, University of Kansas Medical Center, Kansas City, Kansas, USA., Shelford T; Center for Inherited Disease Research, Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Siddiqui N; Department of Gynaecological Oncology, Glasgow Royal Infirmary, Glasgow, UK., Side LE; North East Thames Regional Genetics Service, Great Ormond Street Hospital for Children NHS Trust, London, UK., Sieh W; Department of Health Research and Policy-Epidemiology, Stanford University School of Medicine, Stanford, California, USA., Singer CF; Department of Obstetrics and Gynecology, Medical University of Vienna and Comprehensive Cancer Center, Vienna, Austria., Sobol H; Département Oncologie Génétique, Institut Paoli-Calmettes, Marseille, France., Song H; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK., Southey MC; Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne, Parkville, Victoria, Australia., Spurdle AB; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Stadler Z; Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Steinemann D; Institute of Human Genetics, Hannover Medical School, Hannover, Germany., Stoppa-Lyonnet D; Service de Génétique Oncologique, Institut Curie, Paris, France., Sucheston-Campbell LE; Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York, USA., Sukiennicki G; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Sutphen R; Epidemiology Center, College of Medicine, University of South Florida, Tampa, Florida, USA., Sutter C; Institute of Human Genetics, Department of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany., Swerdlow AJ; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.; Division of Breast Cancer Research, Institute of Cancer Research, London, UK., Szabo CI; National Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA., Szafron L; Department of Pathology and Laboratory Diagnostics, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland., Tan YY; Department of Obstetrics and Gynecology, Medical University of Vienna and Comprehensive Cancer Center, Vienna, Austria., Taylor JA; Epidemiology Branch, Division of Intramural Research, National Institute of Environmental Health Sciences, US National Institutes of Health, Research Triangle Park, North Carolina, USA., Tea MK; Department of Obstetrics and Gynecology, Medical University of Vienna and Comprehensive Cancer Center, Vienna, Austria., Teixeira MR; Department of Genetics, Portuguese Oncology Institute, Porto, Portugal.; Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal., Teo SH; Cancer Research Initiatives Foundation, Sime Darby Medical Centre, Subang Jaya, Malaysia.; University Malaya Cancer Research Institute, Faculty of Medicine, University Malaya Medical Centre, University Malaya, Kuala Lumpur, Malaysia., Terry KL; Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Thompson PJ; Cancer Prevention and Control, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Thomsen LCV; Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway.; Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Bergen, Norway., Thull DL; Magee-Womens Hospital of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Tihomirova L; Latvian Biomedical Research and Study Centre, Riga, Latvia., Tinker AV; Ovarian Cancer Research (OVCARE) Program-Cheryl Brown Ovarian Cancer Outcomes Unit (CBOCOU), BC Cancer Agency, Vancouver, British Columbia, Canada., Tischkowitz M; Program in Cancer Genetics, Departments of Human Genetics and Oncology, McGill University, Montreal, Quebec, Canada.; Department of Medical Genetics, Addenbrooke's Treatment Centre, Addenbrooke's Hospital, Cambridge, UK., Tognazzo S; Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy., Toland AE; Division of Human Cancer Genetics, Departments of Internal Medicine and Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, Ohio State University, Columbus, Ohio, USA., Tone A; Division of Gynecologic Oncology, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada., Trabert B; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA., Travis RC; Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Trichopoulou A; Hellenic Health Foundation, Athens, Greece.; WHO Collaborating Center for Nutrition and Health, Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Athens, Greece., Tung N; Department of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Tworoger SS; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., van Altena AM; Division of Gynecologic Oncology, Department of Obstetrics and Gynaecology, Radboud University Medical Centre, Nijmegen, the Netherlands., Van Den Berg D; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA., van der Hout AH; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., van der Luijt RB; Department of Medical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands., Van Heetvelde M; Center for Medical Genetics, Ghent University, Ghent, Belgium., Van Nieuwenhuysen E; Division of Gynecologic Oncology, Department of Obstetrics and Gynaecology and Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium., van Rensburg EJ; Cancer Genetics Laboratory, Department of Genetics, University of Pretoria, Pretoria, South Africa., Vanderstichele A; Division of Gynecologic Oncology, Department of Obstetrics and Gynaecology and Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium., Varon-Mateeva R; Institute of Medical and Human Genetics, Charité Universitätsmedizin, Campus Virchov Klinikum, Berlin, Germany., Vega A; Fundación Pública Galega de Medicina Xenómica, Servizo Galego de Saúde (SERGAS), Instituto de Investigación Sanitaria (IDIS), Santiago de Compostela, Spain.; Grupo de Medicina Xenómica, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Universidade de Santiago de Compostela (USC), Santiago de Compostela, Spain., Edwards DV; Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt Medical School, Nashville, Tennessee, USA.; Vanderbilt-Ingram Cancer Center, Vanderbilt School of Medicine, Nashville, Tennessee, USA.; Vanderbilt Genetics Institute and Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Vergote I; Division of Gynecologic Oncology, Department of Obstetrics and Gynaecology and Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium., Vierkant RA; 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Publikováno v: Nature genetics [Nat Genet] 2017 May; Vol. 49 (5), pp. 680-691. Date of Electronic Publication: 2017 Mar 27.