Zobrazeno 1 - 10
of 406
pro vyhledávání: '"Kazuyuki SUGAHARA"'
Autor:
Wing Lee Chan, Magdalena Steiner, Tomasz Witkos, Johannes Egerer, Björn Busse, Shuji Mizumoto, Jan M Pestka, Haikuo Zhang, Ingrid Hausser, Layal Abo Khayal, Claus-Eric Ott, Mateusz Kolanczyk, Bettina Willie, Thorsten Schinke, Chiara Paganini, Antonio Rossi, Kazuyuki Sugahara, Michael Amling, Petra Knaus, Danny Chan, Martin Lowe, Stefan Mundlos, Uwe Kornak
Publikováno v:
PLoS Genetics, Vol 14, Iss 3, p e1007242 (2018)
Gerodermia osteodysplastica (GO) is characterized by skin laxity and early-onset osteoporosis. GORAB, the responsible disease gene, encodes a small Golgi protein of poorly characterized function. To circumvent neonatal lethality of the GorabNull full
Externí odkaz:
https://doaj.org/article/d57661c1748c402db63c5dbeb8b9b7d0
Publikováno v:
Molecules, Vol 20, Iss 3, Pp 3527-3548 (2015)
With recent advances in the construction of synthetic glycans, selective targeting of the extracellular matrix (ECM) as a potential treatment for a wide range of diseases has become increasingly popular. The use of compounds that mimic the structure
Externí odkaz:
https://doaj.org/article/8e1b58d55ae34f699e1ab235649335ca
Autor:
Kenji Suzuki, Somasundaram Arumugam, Junji Yokoyama, Yusuke Kawauchi, Yutaka Honda, Hiroki Sato, Yutaka Aoyagi, Shuji Terai, Kazuichi Okazaki, Yasuo Suzuki, Shuji Mizumoto, Kazuyuki Sugahara, Raja Atreya, Markus F Neurath, Kenichi Watanabe, Taishi Hashiguchi, Hiroyuki Yoneyama, Hitoshi Asakura
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158967 (2016)
Induction of mucosal healing (MH) is an important treatment goal in inflammatory bowel disease (IBD). Although the molecular mechanisms underlying MH in IBD is not fully explored, local fibrosis would contribute to interfere mucosal repair. Carbohydr
Externí odkaz:
https://doaj.org/article/bdc39cdabfa94c89bba24d1bfc1d6290
Publikováno v:
Biomolecules, Vol 2, Iss 4, Pp 549-563 (2012)
Chondroitin sulfate (CS) chains are involved in the regulation of various biological processes. However, the mechanism underlying the catabolism of CS is not well understood. Hyaluronan (HA)-degrading enzymes, the hyaluronidases, are assumed to act a
Externí odkaz:
https://doaj.org/article/8e94d2c40b28475b9d70a24f6bfa4778
Publikováno v:
Pharmaceuticals, Vol 10, Iss 2, p 34 (2017)
The indispensable roles of dermatan sulfate-proteoglycans (DS-PGs) have been demonstrated in various biological events including construction of the extracellular matrix and cell signaling through interactions with collagen and transforming growth fa
Externí odkaz:
https://doaj.org/article/037fcdc379f5493cacd5226b53c770cf
Autor:
Kazuyuki Sugahara, Kuntebommanahalli N. Thimmaiah, Hemant K. Bid, Peter J. Houghton, Kanchugarakoppal S. Rangappa
Publikováno v:
PLoS ONE, Vol 7, Iss 10 (2012)
Externí odkaz:
https://doaj.org/article/b3bbf651e07a4120ae72fc21b2634622
Anti-tumor activity of a novel HS-mimetic-vascular endothelial growth factor binding small molecule.
Autor:
Basappa, Kazuyuki Sugahara, Kuntebommanahalli N Thimmaiah, Hemant K Bid, Peter J Houghton, Kanchugarakoppal S Rangappa
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e39444 (2012)
The angiogenic process is controlled by variety of factors of which the vascular endothelial growth factor (VEGF) pathway plays a major role. A series of heparan sulfate mimetic small molecules targeting VEGF/VEGFR pathway has been synthesized. Among
Externí odkaz:
https://doaj.org/article/20817d342bac4f34b366d6a77947dedf
Publikováno v:
Encyclopedia of Marine Biotechnology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f61211ea48732bcb69522dd4b6916cf3
https://doi.org/10.1002/9781119143802.ch94
https://doi.org/10.1002/9781119143802.ch94
Autor:
Yuya, Hirata, Kazuyuki, Sugahara, Hiroki, Hanaiwa, Yumiko, Funashima, Kenichi, Sato, Zenzo, Nagasawa, Tsukuru, Umemura
Publikováno v:
Rinsho Biseibutsu Jinsoku Shindan Kenkyukai shi = JARMAM : Journal of the Association for Rapid Method and Automation in Microbiology. 29(2)
Genetic testing is widely used as a rapid diagnostic method to identify microorganisms and detect antibiotic resistance genes. The nucleic acid to be analyzed is located inside the cell wall, the cell membrane or nuclear envelope. Therefore, it is es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::befb884fb944e5f293c8ce7ed6417b76
https://pubmed.ncbi.nlm.nih.gov/32312079
https://pubmed.ncbi.nlm.nih.gov/32312079
Autor:
Susanne Greber-Platzer, Nicholas Katsanis, Marie T. McDonald, Andrea Superti-Furga, Kazuyuki Sugahara, Azita Sadeghpour, Sheila Unger, Shuji Mizumoto, Shuhei Yamada, Gundula Povysil, Erica E. Davis, Andreas R. Janecke, Kristen L. Deak, Julia Vodopiutz
Publikováno v:
Human mutation, vol. 41, no. 3, pp. 655-667
Human Mutation
Human Mutation
Congenital disorders of glycosylation (CDGs) comprise a large number of inherited metabolic defects that affect the biosynthesis and attachment of glycans. CDGs manifest as a broad spectrum of disease, most often including neurodevelopmental and skel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbedb42bb51947847e8b5ad0946ac2c2
https://serval.unil.ch/resource/serval:BIB_CED95552EEA3.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_CED95552EEA3.P001/REF.pdf
