Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Kazuyuki Ohbo"'
Autor:
Kuniko Nakajima, Michio Ono, Uroš Radović, Selma Dizdarević, Shin-ichi Tomizawa, Kazushige Kuroha, Go Nagamatsu, Ikue Hoshi, Risa Matsunaga, Takayuki Shirakawa, Takeyuki Kurosawa, Yasunari Miyazaki, Masahide Seki, Yutaka Suzuki, Haruhiko Koseki, Masataka Nakamura, Toshio Suda, Kazuyuki Ohbo
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 11 (2019)
Respiratory failure is a life-threatening problem for pre-term and term infants, yet many causes remain unknown. Here, we present evidence that whey acidic protein (WAP) four-disulfide core domain protease inhibitor 2 (Wfdc2), a protease inhibitor pr
Externí odkaz:
https://doaj.org/article/c5db7c6824344c40bb55ac34c501e550
Autor:
Shin-ichi Tomizawa, Fellows, Rachel, Michio Ono, Kazushige Kuroha, Dočkal, Ivana, Yuki Kobayashi, Keisuke Minamizawa, Koji Natsume, Kuniko Nakajima, Ikue Hoshi, Shion Matsuda, Masahide Seki, Yutaka Suzuki, Kazushi Aoto, Hirotomo Saitsu, Kazuyuki Ohbo
Publikováno v:
Development (09501991); Sep2024, Vol. 151 Issue 18, p1-15, 15p
Autor:
Yasushi Yabuki, Takeshi Mizuguchi, Hiromi Fukuda, Jun Sone, Satoko Miyatake, Satomi Mitsuhashi, Eriko Koshimizu, Kohei Hamanaka, Yuji Takahashi, Kazuyuki Ohbo, Aaron M. Wenger, Fumiaki Tanaka, Ken Saida, Naomichi Matsumoto, Naomi Tsuchida, Daisuke Yamaguchi, Yuri Uchiyama, Yuki Satake, Keisuke Morihara, Hiroshi Doi, Atsushi Fujita, Kristofor Nyquist, Tomoko Okamoto, Norifumi Shioda
Publikováno v:
Clinical Epigenetics
Background GGC repeat expansions in NOTCH2NLC are associated with neuronal intranuclear inclusion disease. Very recently, asymptomatic carriers with NOTCH2NLC repeat expansions were reported. In these asymptomatic individuals, the CpG island in NOTCH
Autor:
Ruken Yaman-Deveci, Kuniko Nakajima, Takashi Ito, Takayuki Shirakawa, Kei-ichiro Ishiguro, Fuyuko Shiotani, Yuki Takada, Fumihito Miura, Shin-ichi Tomizawa, Haruhiko Koseki, Jafar Sharif, Yoko Koseki, Michio Ono, Kazuyuki Ohbo
Publikováno v:
Development. 148
Heterochromatin-related epigenetic mechanisms, such as DNA methylation, facilitate pairing of homologous chromosomes during the meiotic prophase of mammalian spermatogenesis. In pro-spermatogonia, de novo DNA methylation plays a key role in completin
Autor:
Tatsukata Kawagoe, Hiromitsu Tanaka, Narumi Ogonuki, Kazuyuki Ohbo, Kimiko Inoue, Shin-ichi Tomizawa, Yuki Kobayashi, Michio Ono, Ivana Dočkal, Yutaka Suzuki, Shogo Matoba, Keisuke Minamizawa, Kazushige Kuroha, Konstantinos Anastassiadis, Atsuo Ogura, Koji Natsume, Selma Dizdarević, Masahide Seki, Nobuhisa Mizuki
Publikováno v:
Development (Cambridge, England). 148(8)
During spermatogenesis, intricate gene expression is coordinately regulated by epigenetic modifiers, which are required for differentiation of spermatogonial stem cells (SSCs) contained among undifferentiated spermatogonia. We have previously found t
Autor:
Yasunari Miyazaki, Mitsuhiro Kishino, Yoshihisa Nukui, Ukihide Tateishi, Masahiro Masuo, Kaori Morota, Tomoya Tateishi, Naoki Nishiyama, Kazuyuki Ohbo
BACKGROUND The clinical course and prognosis of progressive fibrosing interstitial lung diseases ( PF-ILDs) vary from individual to individual. Predictive serum biomarkers for the management of the disease are needed. Serum human epididymis protein 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c2919507a42b8d96bed5b7dfa4c1b2
https://doi.org/10.21203/rs.3.rs-18084/v1
https://doi.org/10.21203/rs.3.rs-18084/v1
Autor:
Yutaka Suzuki, Shin-ichi Tomizawa, Kazuyuki Ohbo, Selma Dizdarević, Masahide Seki, Kuniko Nakajima, Takayuki Shirakawa, Kazushige Kuroha, Risa Matsunaga, Haruhiko Koseki, Yasunari Miyazaki, Uroš Radović, Michio Ono, Takeyuki Kurosawa, Ikue Hoshi, Masataka Nakamura, Toshio Suda, Go Nagamatsu
Publikováno v:
Disease Models & Mechanisms.
Respiratory failure is a life-threatening problem for pre-term and term infants, yet many causes remain unknown. Here, we present evidence that whey acidic protein (WAP) four-disulfide core domain protease inhibitor 2 (Wfdc2), a protease inhibitor pr
Autor:
A. Francis Stewart, Shin-ichi Tomizawa, Sukhdeep Singh, Dimitra Alexopoulou, Yuki Kobayashi, Konstantinos Anastassiadis, Keita Mizoguchi, Ikue Hoshi, Hélène Royo, Kuniko Nakajima, Antoine H.F.M. Peters, Jun Nakabayashi, Takayuki Shirakawa, Yutaka Suzuki, Kazuyuki Ohbo, Kumiko Watanabe, Andreas Dahl, Masahide Seki
Publikováno v:
Development. 145
The mammalian male germline is sustained by a pool of spermatogonial stem cells (SSCs) that can transmit both genetic and epigenetic information to offspring. However, the mechanisms underlying epigenetic transmission remain unclear. The histone meth
Autor:
Kazuteru Hasegawa, Rie Saba, Takayuki Shirakawa, Aiko Sada, Kazuyuki Ohbo, Yumiko Saga, Quan Wu, Zhi Zhou
Publikováno v:
Developmental Cell. 34:96-107
SummaryIn many adult tissues, homeostasis relies on self-renewing stem cells that are primed for differentiation. The reconciliation mechanisms of these characteristics remain a fundamental question in stem cell biology. We propose that regulation at
Autor:
Shin-ichi Tomizawa, Kazuyuki Ohbo
Publikováno v:
Biomolecular Concepts, Vol 6, Iss 1, Pp 1-9 (2015)
Stem cells are identified classically by an in vivo transplantation assay plus additional characterization, such as marker analysis, linage-tracing and in vitro/ex vivo differentiation assays. Stem cell lines have been derived, in vitro, from adult t