Výsledky vyhledávání - "Kazuyuki Naitoh"

Roles of Cx43-associated protein kinases in suppression of gap junction-mediated chemical coupling by ischemic preconditioning

Autor: Kazuyuki Naitoh, Yoshiaki Terashima, T Sato, Tetsuji Miura, Takahito Itoh, Toshiyuki Yano, Masaya Tanno, Takayuki Miki, Kazuaki Shimamoto, Hiroyuki Hotta

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 296:H396-H403

Ischemic preconditioning (PC) suppresses chemical coupling of cardiomyocytes via gap junctions (GJs) during ischemia, which is an adjunct mechanism of protection. The aim of this study was to characterize roles of protein kinases in PC-induced GJ mod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b591f64b3b3d1f39daded1f3ebb1a0b2
https://doi.org/10.1152/ajpheart.00448.2008

Zobrazit plný text záznamu

δ-Opioid receptor activation before ischemia reduces gap junction permeability in ischemic myocardium by PKC-ε-mediated phosphorylation of connexin 43

Autor: Kazuaki Shimamoto, Kazuyuki Naitoh, Tetsuji Miura, Takayuki Miki, Masahiro Nishihara, Toshiyuki Yano, Masaya Tanno

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 293:H1425-H1431

The aim of this study was to examine the hypothesis that δ-opioid receptor activation before ischemia suppresses gap junction (GJ) permeability by PKC-mediated connexin 43 (Cx43) modulation, which contributes to infarct size limitation afforded by t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51bd95dbf702e1f609cf36e50d34c70f
https://doi.org/10.1152/ajpheart.01115.2006

Zobrazit plný text záznamu

Impairment of cardioprotective PI3K-Akt signaling by post-infarct ventricular remodeling is compensated by an ERK-mediated pathway

Autor: Masahiro Nishihara, Kazuaki Shimamoto, Kazuyuki Naitoh, Masaya Tanno, Takayuki Miki, T Sato, Tetsuji Miura, Akari Takahashi

Publikováno v: Basic Research in Cardiology. 102:163-170

Recently we found that post-infarct remodeling disrupts PI3KAkt signaling triggered by erythropoietin (EPO) but an unknown compensatory mechanism preserves EPO-induced protection against infarction in those hearts. In this study, we examined the poss

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e71d777d40d80a4b98e5bd79c94a73
https://doi.org/10.1007/s00395-006-0622-3

Zobrazit plný text záznamu

MitoKATP channel activation suppresses gap junction permeability in the ischemic myocardium by an ERK-dependent mechanism

Autor: Masahiro Nishihara, Yoshihiko Ichikawa, Yuichi Nakamura, Yoshihiro Ikeda, Hironori Kobayashi, Tetsuji Miura, Takayuki Miki, Katsuhiko Ohori, Kazuaki Shimamoto, Kazuyuki Naitoh

Publikováno v: Cardiovascular Research. 70:374-383

Ischemic preconditioning accelerates suppression of gap junction (GJ) permeability during myocardial ischemia, and GJ blockers reduce infarct size. We hypothesized that the mitochondrial ATP-sensitive K+ (mitoKATP) channel is one of the mechanisms re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1b8e67cf4f09d8d2b951d77bd58757a
https://doi.org/10.1016/j.cardiores.2006.01.023

Zobrazit plný text záznamu

Alteration in Erythropoietin-Induced Cardioprotective Signaling by Postinfarct Ventricular Remodeling

Autor: Akari Takahashi, Takayuki Miki, Hironori Kobayashi, Kazuaki Shimamoto, Kazuyuki Naitoh, Masahiro Nishihara, Tetsuji Miura, Jun Sakamoto, Yoshihiro Ikeda, Masaya Tanno, Katsuhiko Ohori, Toshiyuki Yano

Publikováno v: Journal of Pharmacology and Experimental Therapeutics. 317:68-75

Postinfarct remodeling impairs mechanisms of ischemic preconditioning. We examined whether myocardial response to activation of the erythropoietin (EPO) receptor is modified by postinfarct remodeling. Four weeks after induction of myocardial infarcti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac940bcfec3f56b8f8c71e0d4b6ac07e
https://doi.org/10.1124/jpet.105.095745

Zobrazit plný text záznamu

Autor: Yoshinori Ito, Nobuhiko Noda, Hiroshi Sao, Kazuyuki Naitoh, Hiroshi Kimura, Hiroatsu Iida, Akane Kunitomi

Publikováno v: ResearcherID

We present a case of life-threatening Epstein-Barr virus (EBV)-associated hemophagocytic lymphohistiocytosis (HLH) with severe hepatitis that was successfully treated by allogeneic stem cell transplantation from an unrelated donor. A 26-year-old woma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58bdee53084b41061ae6c42c399bfec7
https://pubmed.ncbi.nlm.nih.gov/21628862

Zobrazit plný text záznamu

Modulation of the mitochondrial permeability transition pore complex in GSK-3beta-mediated myocardial protection

Autor: Hiroyuki Hotta, Katsuhiko Ohori, Toshiyuki Yano, Takayuki Miki, Yoshiaki Terashima, Masahiro Nishihara, Masaya Tanno, Tetsuji Miura, Kazuaki Shimamoto, Kazuyuki Naitoh

Publikováno v: Journal of molecular and cellular cardiology. 43(5)

Recently we found that the level of anti-infarct tolerance afforded by ischemic preconditioning (IPC) and erythropoietin (EPO) infusion was closely correlated with the level of Ser9-phospho-GSK-3beta upon reperfusion in the heart. To get an insight i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e3b1218f8d4a9f56770a8cea642ae01
https://pubmed.ncbi.nlm.nih.gov/17931653

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání