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pro vyhledávání: '"Kazuyuki Kitazawa"'
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Kitazawa et al. show that chondroitin 6-sulfate represses keratinocyte proliferation in skin. They find that mice deficient in chondroitin-6-O-sulfotransferase-1 (C6st-1), which synthesizes chondroitin 6-sulfate, exhibit keratinocyte hyperproliferati
Externí odkaz:
https://doaj.org/article/f5ee692e9c0645bdbe1c36a9b082fc46
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications Biology
Communications Biology
Chondroitin sulfates are implicated in epidermal biology, but functional significance of chondroitin sulfates remains unclear. Here, we report that chondroitin 6-sulfate is important for the maintenance of epidermal homeostasis. Mice deficient in cho
Autor:
Mina Musashi, Nanako Nagasawa-Shimura, Yoshiki Kubota, Teruaki Nagasawa, Kazuyuki Kitazawa, Yoko Yamaguchi, Kazunori Tanaka
Publikováno v:
Biologicalpharmaceutical bulletin. 44(11)
Acetylcholine (ACh), a quaternary ammonium cation, is known as one of the itch inducer in atopic dermatitis (AD), an inflammatory skin disease with intense itching. Previous research has reported accumulation of ACh in lesional site of AD patients. G