Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Kazuyuki Fuji"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 123, Iss 4, Pp 402-406 (2013)
Several lines of evidence indicate that serotonin type 7 (5-HT7) receptors play a critical role for non-photic resetting of the mammalian circadian clock; however, the contributions of other types of 5-HT receptors to non-photic entrainment are not y
Externí odkaz:
https://doaj.org/article/a59a50b3405f40408bcd8f5320355226
Autor:
Kiyotaka Mukasa, Yusuke Nuruki, Hayato Kubo, Yoshihide Narahara, Motohiro Umehara, Kazuyuki Fujie
Publikováno v:
IEEE Transactions on Quantum Engineering, Vol 5, Pp 1-4 (2024)
Sapphire substrates have recently been recognized for their potential to improve the coherence time of superconducting qubits. However, due to challenges in via fabrication, silicon substrates have been predominantly used for qubits. In this study, w
Externí odkaz:
https://doaj.org/article/f57436eec1614becab56e9b61e282bfe
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114262- (2024)
Summary: The anaphase-promoting complex/cyclosome (APC/C) is a critical and tightly regulated E3 ligase that orchestrates the cellular life cycle by controlling the degradation of cell cycle regulators. An intriguing feature of this complex is an aut
Externí odkaz:
https://doaj.org/article/f9c736b7e15a4c4bab2cc12d41aaa0f8
Autor:
Kim Hou Chia, Hiroko Takaki, Kazuyuki Fujimitsu, Sarah Darling, Juan Zou, Juri Rappsilber, Hiroyuki Yamano
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114155- (2024)
Summary: Cell cycle control relies on a delicate balance of phosphorylation with CDK1 and phosphatases like PP1 and PP2A-B55. Yet, identifying the primary substrate responsible for cell cycle oscillations remains a challenge. We uncover the pivotal r
Externí odkaz:
https://doaj.org/article/35866ab49860443e8550a7f6c98ee1ba
Publikováno v:
Journal of Pharmacological Sciences, Vol 123, Iss 4, Pp 402-406 (2013)
Several lines of evidence indicate that serotonin type 7 (5-HT7) receptors play a critical role for non-photic resetting of the mammalian circadian clock; however, the contributions of other types of 5-HT receptors to non-photic entrainment are not y
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
ObjectiveTo elucidate the functional role of gamma-aminobutyric acid (GABA)-ergic inhibition in suppressing epileptic brain activities such as spike-wave discharge (SWD), we recorded electroencephalogram (EEG) in knockout rats for Glutamate decarboxy
Externí odkaz:
https://doaj.org/article/d6f639ea46da4c14a887146e11c78add
Autor:
Kazuyuki Fujihara
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Abnormalities in the γ-aminobutyric acid (GABA) system have been reported in the postmortem brains of individuals with schizophrenia. In particular, the reduction of one of the GABA-synthesizing enzymes, the 67-kDa isoform of glutamate decarboxylase
Externí odkaz:
https://doaj.org/article/b70b22497eeb4becad2dc862ab7a8a36
Autor:
Kazuki Komiyama, Keiya Iijima, Reika Kawabata-Iwakawa, Kazuyuki Fujihara, Toshikazu Kakizaki, Yuchio Yanagawa, Yuhei Yoshimoto, Shigeo Miyata
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Patients with glioma often demonstrate epilepsy. We previously found burst discharges in the peritumoral area in patients with malignant brain tumors during biopsy. Therefore, we hypothesized that the peritumoral area may possess an epilepti
Externí odkaz:
https://doaj.org/article/2a9fc90b7c3f4773a9541386570ff426
Autor:
Isao Kato, Haruyasu Yamaguchi, Masatoshi Fujishima, Shunsaku Hirai, Takatoshi Ishikawa, Yoshiaki Komiya, Kenji Toba, Kei Maruyama, Takaaki Hasegawa, Hideaki Oda, Hideo Kawano, Yutaka Kiyohara, Ken Nakagawa, Seikoh Horiuchi, Eiju Tsuchiya, Yasuhide Nakashima, Taketo Yoshitake, Norie Araki, Nobuo Nemoto, Tsuneo Yamazaki, Kazuyuki Fuji, Thomas N. Tulenko, Xaoyan Sun, Yoshihiro Kumagae, Atsumi Nitta, Kazuhito Yamashita, Mihoko Usami, Yasuyoshi Ouchi, Shoichi Ishiura, Yasujirou Sakai, Tsuyoshi Kawarabayashi, Jing Liang, Yumiko Saito, Hiromi Tasaki, Kunihiko Obata, Yoko Nakatsuru, Toshitaka Nabeshima, Takao Ohmura, Tomoko Tashiro, Kazuo Ueda, Masahiro Akishita, Wakako Yamao-Harigaya, Seiichi Kawashima, Hajime Orimo, Tsutomu Kameyama, Akio Kuroiwa
Publikováno v:
Gerontology. 40:I-IV
Publikováno v:
Neuroscience Letters. 150:99-102
Basal forebrain (BF) lesions induced by ibotenic acid produced increases in the Bmax and Kd values of [3H]QNB binding sites in the frontal cortex, parietal cortex, and hippocampus. Twenty-eight-day successive administration of propentofylline (10 and