Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kazuyuki Akane"'
Autor:
Yan Xing, Shigeo Murata, Keiji Tanaka, Haruhiko Suzuki, Stephen C. Jameson, Alfred Singer, Yousuke Takahama, François Van Laethem, Kazuyuki Akane, Kensuke Takada
Publikováno v:
Nature Immunology. 16:1069-1076
In the thymus, low-affinity T cell antigen receptor (TCR) engagement facilitates positive selection of a useful T cell repertoire. Here we report that TCR responsiveness of mature CD8(+) T cells is fine tuned by their affinity for positively selectin
Publikováno v:
Immunology. 139:309-317
We identified CD8(+) CD122(+) regulatory T cells (CD8(+) CD122(+) Treg cells) and reported their importance in maintaining immune homeostasis. The absence of CD8(+) CD122(+) Treg cells has been shown to lead to severe systemic autoimmunity in several
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 113(9)
The Fas/FasL (CD95/CD178) system is required for immune regulation; however, it is unclear in which cells, when, and where Fas/FasL molecules act in the immune system. We found that CD8(+)CD122(+) cells, which are mostly composed of memory T cells in
Autor:
Muhaimin Rifa'i, Ken-ichi Isobe, Zhe Shi, Haruhiko Suzuki, Kazuyuki Akane, Agustina Tri Endharti, Yusuke Okuno
Publikováno v:
European Journal of Immunology. 39:2106-2119
The importance of CD8(+)CD122(+) Treg in the maintenance of immune homeostasis has been previously demonstrated in mice. Because the expression pattern of CD8 and CD122 in humans is different from that in mice, human CD8(+) Treg that correspond to th
Autor:
Asahito Hama, Seiji Kojima, Itzel Bustos Villalobos, Taichi Kato, Kazuyuki Akane, Yinyan Xu, Yusuke Okuno, Hideki Muramatsu, Yu Hirabayashi, Shinji Hasegawa, Yoshiyuki Takahashi
Publikováno v:
European journal of pediatrics. 172(6)
The aim of this study was to investigate changes in CD4(+)CD25(+)FOXP3(+) regulatory T cells (Tregs) throughout the clinical course of Kawasaki disease (KD) and correlations with response to intravenous immunoglobulin (IVIg) therapy. Participants com
Autor:
Zhe, Shi, Yusuke, Okuno, Muhaimin, Rifa'i, Agustina Tri, Endharti, Kazuyuki, Akane, Ken-Ichi, Isobe, Haruhiko, Suzuki
Publikováno v:
European journal of immunology. 39(8)
The importance of CD8(+)CD122(+) Treg in the maintenance of immune homeostasis has been previously demonstrated in mice. Because the expression pattern of CD8 and CD122 in humans is different from that in mice, human CD8(+) Treg that correspond to th
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 3/1/2016, Vol. 113 Issue 9, p2460-2465, 6p