Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kazuyoshi Yamaoka"'
Publikováno v:
Bulletin of the Chemical Society of Japan. 81:1599-1604
Affinity chromatography is widely utilized as a tool in biomedical research and biotechnology. This purification method provides increased sensitivity for various kinds of analyses, such as mass sp...
Publikováno v:
Current Opinion in Nephrology & Hypertension. 16:297-304
Vitamin D has diverse biological actions, and consequently the mechanisms behind how it regulates gene transcription are diverse. Unlike its well described positive effects on gene transcription, little is known about how vitamin D induces transcript
Autor:
Yoko Yamamoto, Kazuyoshi Yamaoka, Shigeaki Kato, Ikuko Yamaoka, Hirochika Kitagawa, Kei Iwasaki, Masayo Shindo
Publikováno v:
Archives of Biochemistry and Biophysics. 460:166-171
Vitamin D receptor (VDR) mediates a wide variety of vitamin D actions through transcriptional controls of target genes as a ligand-dependent transcription factor. The transactivation by VDR is known to associate with two co-activator complexes, DRIP/
Autor:
Yanfei Ma, Qing Q. Zeng, Berket Khalifa, William W. Chin, Keith R. Stayrook, Ai Memezawa, Kazuyoshi Yamaoka, Subba R. Chintalacharuvu, Shigeaki Kato, Srinivasan Chandrasekhar, Jianfen Lu, Kelli S. Bramlett, Sunil Nagpal, Xiao-Peng Yu, Ying K. Yee, Yoko Yamamoto, Stephen J. Iturria, Thomas P. Burris, Linebarger Jared Harris, Rajesh S. Savkur
Publikováno v:
Journal of Clinical Investigation. 116:892-904
Vitamin D receptor (VDR) ligands are therapeutic agents for the treatment of psoriasis, osteoporosis, and secondary hyperparathyroidism. VDR ligands also show immense potential as therapeutic agents for autoimmune diseases and cancers of skin, prosta
Autor:
Yasuharu Nishimura, Masatake Oiso, Sho Matsushita, Kenji Yone, Tohru Nishi, Takayuki Kanai, Kazuyoshi Yamaoka
Publikováno v:
International Immunology. 8:757-764
The frequency of the HLA-DR4-DQ4 haplotype (DRB1(*)0405-DQA1(*)0302-DQB1(*)0401) is significantly increased in Japanese patients with rheumatoid arthritis (RA) and DRB1(*)0405-binding peptide motifs were identified in our previous studies. To clarify
Autor:
Katsutoshi Hori, Kazuo Shishido, Kazuyoshi Yamaoka, Takeshi Saito, Susumu Kajiwara, Tetsuya Kanno, Hiroshi Miyazawa
Publikováno v:
Gene. 114:173-178
Screening for gene(s) homologous to v-Ha-ras (Harvey rat sarcoma viral ras gene) in the basidiomycete, Lentinus edodes, resulted in the isolation of a novel gene (designated priA), in addition to a ras gene homologue [Hori et al., Gene 105 (1991) 91-
Autor:
Yoshihiro Mezaki, Takashi Kamimura, Shun Sawatsubashi, Ken-ichi Takeyama, Ichiro Takada, Eiji Ochiai, Kazuyoshi Yamaoka, Yoshiaki Azuma, Mi Sun Kim, Shigeaki Kato, Hirochika Kitagawa, Yu Tsushima, Sally Fujiyama, Ken Ichiro Takagi
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 25(5)
Vitamin D plays an important role in regulating bone and calcium metabolism. The actions of vitamin D are mediated through the nuclear vitamin D receptor (VDR), and gene disruption of the VDR in mice causes skeletal disorders. However, the precise ro
Autor:
Shigeaki Kato, Akiko Murayama, Ken-ichi Takeyama, Hirochika Kitagawa, Masatomo Mihara, Mi Sun Kim, Kazuyoshi Yamaoka, Ryoji Fujiki, Yoko Yamamoto
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 21(2)
Although transactivation by the liganded vitamin D receptor (VDR) is well described at the molecular level, the precise molecular mechanism of negative regulation by the liganded VDR remains to be elucidated. We have previously reported a novel class
Autor:
Kazuyoshi, Yamaoka, Masayo, Shindo, Kei, Iwasaki, Ikuko, Yamaoka, Yoko, Yamamoto, Hirochika, Kitagawa, Shigeaki, Kato
Publikováno v:
Archives of biochemistry and biophysics. 460(2)
Vitamin D receptor (VDR) mediates a wide variety of vitamin D actions through transcriptional controls of target genes as a ligand-dependent transcription factor. The transactivation by VDR is known to associate with two co-activator complexes, DRIP/
Autor:
Yasumasa Sasaki, Kazuyoshi Yamaoka, Shinichiro Takezawa, Takashi Nakamura, Shigeaki Kato, Masahiko Kishimoto, Ryoji Fujiki, Hirochika Kitagawa
Publikováno v:
Endocrine journal. 53(2)
Nuclear steroid/thyroid vitamin A/D receptor genes form a gene superfamily and encode DNA-binding transcription factors that control the transcription of target genes in a ligand-dependent manner. It has become clear that chromatin remodeling and the