Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Kazuyoshi Kumagai"'
Autor:
Zhishan Wang, Ping Yang, Jie Xie, Hsuan-Pei Lin, Kazuyoshi Kumagai, Jack Harkema, Chengfeng Yang
Publikováno v:
Environment International, Vol 137, Iss , Pp - (2020)
Arsenic and benzo[a]pyrene (BaP) are among the most common environmental carcinogens causing lung cancer. Millions of people are exposed to arsenic through consuming arsenic-contaminated drinking water. High levels of BaP are found in well-done barbe
Externí odkaz:
https://doaj.org/article/70a3d05e335541d5be4bd32eebbcf4c0
Autor:
Kelly A. Fader, Rance Nault, Chen Zhang, Kazuyoshi Kumagai, Jack R. Harkema, Timothy R. Zacharewski
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Abstract 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a persistent environmental contaminant which elicits hepatotoxicity through activation of the aryl hydrocarbon receptor (AhR). Male C57BL/6 mice orally gavaged with TCDD (0.01–30 µg/kg) every
Externí odkaz:
https://doaj.org/article/dfa70fdef3ce4540b2a3007793bde343
Autor:
Melissa A Bates, Christina Brandenberger, Ingeborg M Langohr, Kazuyoshi Kumagai, Adam L Lock, Jack R Harkema, Andrij Holian, James J Pestka
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0220469 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0160622.].
Externí odkaz:
https://doaj.org/article/3b06caeb631a4695a96d6d144cbb67ab
Autor:
Melissa A Bates, Christina Brandenberger, Ingeborg M Langohr, Kazuyoshi Kumagai, Adam L Lock, Jack R Harkema, Andrij Holian, James J Pestka
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171877 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0160622.].
Externí odkaz:
https://doaj.org/article/fbe944e60187448f820489221fcf2ecc
Autor:
Melissa A Bates, Christina Brandenberger, Ingeborg I Langohr, Kazuyoshi Kumagai, Adam L Lock, Jack R Harkema, Andrij Holian, James J Pestka
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160622 (2016)
Occupational exposure to respirable crystalline silica (cSiO2, quartz) is etiologically linked to systemic lupus erythematosus (lupus) and other human autoimmune diseases (ADs). In the female NZBWF1 mouse, a widely used animal model that is genetical
Externí odkaz:
https://doaj.org/article/8ff0158e2cdd4fb68ddc38eebcfa45e6
Publikováno v:
Journal of Pharmacological Sciences, Vol 110, Iss 1, Pp 47-54 (2009)
Abstract.: It is largely unknown whether hyperlipidemia is involved in the pathobiology of renal ischemia–reperfusion (I/R) injury that is an important cause of acute kidney injury. Here we studied the effect of experimental dyslipidemia on renal I
Externí odkaz:
https://doaj.org/article/5e10e11bec5c4728b4e0add157248cb4
Autor:
Melissa A Bates, Christina Brandenberger, Ingeborg Langohr, Kazuyoshi Kumagai, Jack R Harkema, Andrij Holian, James J Pestka
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125481 (2015)
Genetic predisposition and environmental factors influence the development of human autoimmune disease. Occupational exposure to crystalline silica (cSiO2) has been etiologically linked to increased incidence of autoimmunity, including systemic lupus
Externí odkaz:
https://doaj.org/article/a3e5d5d2ba0e423fa2ac41745bf9eb6a
Autor:
Toshinori Agatsuma, Yuki Abe, Takashi Nakada, Ichiro Hayakawa, Tetsuo Aida, Tomoko Shibutani, Yumi Nishiya, Akiko Watanabe, Kazuyoshi Kumagai, Chiharu Hattori, Takanori Maejima, Jun Hasegawa, Michiko Yamato
Supplementary Data from DS-7300a, a DNA Topoisomerase I Inhibitor, DXd-Based Antibody–Drug Conjugate Targeting B7-H3, Exerts Potent Antitumor Activities in Preclinical Models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2555c866d4671115aaf3d352455d62eb
https://doi.org/10.1158/1535-7163.22521898.v1
https://doi.org/10.1158/1535-7163.22521898.v1
Autor:
Toshinori Agatsuma, Yuki Abe, Takashi Nakada, Ichiro Hayakawa, Tetsuo Aida, Tomoko Shibutani, Yumi Nishiya, Akiko Watanabe, Kazuyoshi Kumagai, Chiharu Hattori, Takanori Maejima, Jun Hasegawa, Michiko Yamato
B7-H3 is overexpressed in various solid tumors and has been considered as an attractive target for cancer therapy. Here, we report the development of DS-7300a, a novel B7-H3–targeting antibody–drug conjugate with a potent DNA topoisomerase I inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a31bd9f9c43f7e981e6be14ca30c4b1
https://doi.org/10.1158/1535-7163.c.6543217
https://doi.org/10.1158/1535-7163.c.6543217
Autor:
Michiko Yamato, Jun Hasegawa, Takanori Maejima, Chiharu Hattori, Kazuyoshi Kumagai, Akiko Watanabe, Yumi Nishiya, Tomoko Shibutani, Tetsuo Aida, Ichiro Hayakawa, Takashi Nakada, Yuki Abe, Toshinori Agatsuma
Publikováno v:
Molecular Cancer Therapeutics. 21:635-646
B7-H3 is overexpressed in various solid tumors and has been considered as an attractive target for cancer therapy. Here, we report the development of DS-7300a, a novel B7-H3–targeting antibody–drug conjugate with a potent DNA topoisomerase I inhi