Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Kazuya Toriumi"'
Autor:
Koichi Tabata, Shuraku Son, Jun Miyata, Kazuya Toriumi, Mitsuhiro Miyashita, Kazuhiro Suzuki, Masanari Itokawa, Hidehiko Takahashi, Toshiya Murai, Makoto Arai
Publikováno v:
Schizophrenia, Vol 10, Iss 1, Pp 1-7 (2024)
Abstract Several studies have shown white matter (WM) dysconnectivity in people with schizophrenia (SZ). However, the underlying mechanism remains unclear. We investigated the relationship between plasma homocysteine (Hcy) levels and WM microstructur
Externí odkaz:
https://doaj.org/article/4e7d67885dff49229588d0c5a28b2ccc
Autor:
Shuraku Son, Makoto Arai, Kazuya Toriumi, Christina Andica, Daisuke Matsuyoshi, Koji Kamagata, Shigeki Aoki, Takahiko Kawashima, Takanori Kochiyama, Tomohisa Okada, Yasutaka Fushimi, Yuji Nakamoto, Yuko Kobayashi, Toshiya Murai, Masanari Itokawa, Jun Miyata
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Carbonyl stress is a condition featuring increased rich reactive carbonyl compounds, which facilitate the formation of advanced glycation end products including pentosidine. We previously reported the relationship between enhanced carbonyl s
Externí odkaz:
https://doaj.org/article/b38a7acf387843b085269d3e6dd0c75e
Autor:
Kazuya Toriumi, Kyoka Iino, Azuna Ozawa, Mitsuhiro Miyashita, Syudo Yamasaki, Kazuhiro Suzuki, Hikari Sugawa, Koichi Tabata, Satoshi Yamaguchi, Satoshi Usami, Masanari Itokawa, Atsushi Nishida, Ryoji Nagai, Hidenori Kamiguchi, Makoto Arai
Publikováno v:
Redox Biology, Vol 67, Iss , Pp 102876- (2023)
Pentosidine (PEN) is an advanced glycation end-product (AGEs), where a fluorescent cross-link is formed between lysine and arginine residues in proteins. Accumulation of PEN is associated with aging and various diseases. We previously reported that a
Externí odkaz:
https://doaj.org/article/669484f5dbf847fe96284e5f9b8b22ea
Autor:
Kazuhiro Suzuki, Syudo Yamasaki, Mitsuhiro Miyashita, Shuntaro Ando, Kazuya Toriumi, Akane Yoshikawa, Miharu Nakanishi, Yuko Morimoto, Sho Kanata, Shinya Fujikawa, Kaori Endo, Shinsuke Koike, Satoshi Usami, Masanari Itokawa, Shinsuke Washizuka, Mariko Hiraiwa-Hasegawa, Herbert Y. Meltzer, Kiyoto Kasai, Atsushi Nishida, Makoto Arai
Publikováno v:
npj Schizophrenia, Vol 8, Iss 1, Pp 1-6 (2022)
Abstract Muscular strength, assessed by handgrip, is a risk indicator for psychiatric disorders, including psychosis. However, the biological mechanisms underlying this association remain unclear. Since advanced glycation end products (AGEs) play a k
Externí odkaz:
https://doaj.org/article/347c475733634683bbb7d3a26c8b12fe
Autor:
Mitsuhiro Miyashita, Syudo Yamasaki, Shuntaro Ando, Kazuhiro Suzuki, Kazuya Toriumi, Yasue Horiuchi, Akane Yoshikawa, Atsushi Imai, Yukihiro Nagase, Yasuhiro Miyano, Tomoko Inoue, Kaori Endo, Yuko Morimoto, Masaya Morita, Tomoki Kiyono, Satoshi Usami, Yuji Okazaki, Toshiaki A. Furukawa, Mariko Hiraiwa-Hasegawa, Masanari Itokawa, Kiyoto Kasai, Atsushi Nishida, Makoto Arai
Publikováno v:
npj Schizophrenia, Vol 7, Iss 1, Pp 1-6 (2021)
Abstract Case control studies have suggested that advanced glycation end products play a key role in the pathophysiology of chronic schizophrenia. However, the longitudinal association between advanced glycation end products and psychotic symptoms am
Externí odkaz:
https://doaj.org/article/b10fdb1ff4164bd08adf27d9376d72df
Autor:
Kazuya Toriumi, Mitsuhiro Miyashita, Kazuhiro Suzuki, Nao Yamasaki, Misako Yasumura, Yasue Horiuchi, Akane Yoshikawa, Mai Asakura, Noriyoshi Usui, Masanari Itokawa, Makoto Arai
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract We have reported that a subpopulation of patients with schizophrenia have lower levels of vitamin B6 (VB6) in peripheral blood than do healthy controls. In a previous study, we found that VB6 level was inversely proportional to the patient
Externí odkaz:
https://doaj.org/article/81fefeaf328045f896f032d2303bed60
Autor:
Akane Yoshikawa, Itaru Kushima, Mitsuhiro Miyashita, Kazuya Toriumi, Kazuhiro Suzuki, Yasue Horiuchi, Hideya Kawaji, Shunya Takizawa, Norio Ozaki, Masanari Itokawa, Makoto Arai
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Previously, we identified a subpopulation of schizophrenia (SCZ) showing increased levels of plasma pentosidine, a marker of glycation and oxidative stress. However, its causative genetic factors remain largely unknown. Recently, it has been
Externí odkaz:
https://doaj.org/article/344a32de85f94468998e7f083575d27c
Autor:
Hyeonsoo Jeong, Isabel Mendizabal, Stefano Berto, Paramita Chatterjee, Thomas Layman, Noriyoshi Usui, Kazuya Toriumi, Connor Douglas, Devika Singh, Iksoo Huh, Todd M. Preuss, Genevieve Konopka, Soojin V. Yi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
DNA methylation plays an important role in brain development and function. Here, the authors compare whole-genome methylation in neurons and oligodendrocytes in humans, chimpanzees and macaques to reconstruct evolution of DNA methylation at cell-type
Externí odkaz:
https://doaj.org/article/0dd08ea30d88455d976faaba5e8d47c1
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/6654ae52f93f49b9a8b1c1b8e80095f1
Autor:
Yuduki Someya, Sakine Kobayashi, Kazuya Toriumi, Shigeki Takeda, Noritaka Adachi, Aya Kurosawa
Publikováno v:
Genes, Vol 14, Iss 2, p 420 (2023)
Natural antioxidants derived from plants exert various physiological effects, including antitumor effects. However, the molecular mechanisms of each natural antioxidant have not yet been fully elucidated. Identifying the targets of natural antioxidan
Externí odkaz:
https://doaj.org/article/459042abda5f4d4d9df1c502bd3047b1