Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Kazuya Togashi"'
Autor:
Ryota Nakahama, Aika Saito, Sensho Nobe, Kazuya Togashi, Ikuo K. Suzuki, Akira Uematsu, Kazuo Emoto
Publikováno v:
Molecular Brain, Vol 15, Iss 1, Pp 1-9 (2022)
Abstract Adeno-associated virus (AAV) vector is a critical tool for gene delivery through its durable transgene expression and safety profile. Among many serotypes, AAV2-retro is typically utilized for dissecting neural circuits with its retrograde f
Externí odkaz:
https://doaj.org/article/d259030ff549453896290520c467b619
Autor:
Kazuya Togashi, Masato Tsuji, Shunsuke Takeuchi, Ryota Nakahama, Hiroyuki Koizumi, Kazuo Emoto
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Neurons typically remodel axons/dendrites for functional refinement of neural circuits in the developing brain. Mitral cells in the mammalian olfactory system remodel their dendritic arbors in the perinatal development, but the underlying molecular a
Externí odkaz:
https://doaj.org/article/9d3b4c049e8b47948f8acba3ab1d040e
Autor:
Yasuko Kitatani, Akane Tezuka, Eri Hasegawa, Satoyoshi Yanagi, Kazuya Togashi, Masato Tsuji, Shu Kondo, Jay Z Parrish, Kazuo Emoto
Publikováno v:
PLoS Genetics, Vol 16, Iss 8, p e1008942 (2020)
To remodel functional neuronal connectivity, neurons often alter dendrite arbors through elimination and subsequent regeneration of dendritic branches. However, the intrinsic mechanisms underlying this developmentally programmed dendrite regeneration
Externí odkaz:
https://doaj.org/article/1ec37522304b4df0bd278ccc10dae8ea
Na+/H+ exchangers induce autophagy in neurons and inhibit polyglutamine-induced aggregate formation.
Autor:
Kazuya Togashi, Shuji Wakatsuki, Akiko Furuno, Shinji Tokunaga, Yoshitaka Nagai, Toshiyuki Araki
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81313 (2013)
In polyglutamine diseases, an abnormally elongated polyglutamine results in protein misfolding and accumulation of intracellular aggregates. Autophagy is a major cellular degradative pathway responsible for eliminating unnecessary proteins, including
Externí odkaz:
https://doaj.org/article/927628d3b37e4d47b4b246f92f5401d8
Autor:
Kazuya Togashi, Kazuo Emoto, Masato Tsuji, Hiroyuki Koizumi, Ikuo K. Suzuki, Shunsuke Takeuchi, Emilia Bergoglio
Publikováno v:
Neuroscience Research. 170:154-165
Doublecortin-like kinase 1 (DCLK1) is a Doublecortin family kinase involved in a range of brain development processes including cell migration, axon/dendrite growth, and synapse development. The Dclk1 gene potentially generates multiple splicing isof
Autor:
Eri Hasegawa, Yasuko Kitatani, Shu Kondo, Jay Z. Parrish, Akane Tezuka, Kazuya Togashi, Satoyoshi Yanagi, Kazuo Emoto, Masato Tsuji
Publikováno v:
PLoS Genetics, Vol 16, Iss 8, p e1008942 (2020)
PLoS Genetics
PLoS Genetics
To remodel functional neuronal connectivity, neurons often alter dendrite arbors through elimination and subsequent regeneration of dendritic branches. However, the intrinsic mechanisms underlying this developmentally programmed dendrite regeneration
Autor:
Joseph G. Gleeson, Hiroyuki Koizumi, Kazuya Togashi, Kazuo Emoto, James Thompson, John R. Yates, Hiromi Fujioka
Publikováno v:
Developmental Neurobiology. 77:493-510
Doublecortin-like kinase 1 (DCLK1) is a member of the neuronal microtubule-associated doublecortin (DCX) family and functions in multiple stages of neural development including radial migration and axon growth of cortical neurons. DCLK1 is suggested
Autor:
Akane Tezuka, Yusuke Dairyo, Natsuko Ishikawa, Kazuya Togashi, Kazuo Emoto, Kei-ichiro Yasunaga, Hiroyuki Koizumi
Publikováno v:
Genes & Development. 29:1763-1775
Sensory neurons with common functions are often nonrandomly arranged and form dendritic territories in stereotypic spatial patterns throughout the nervous system, yet molecular mechanisms of how neurons specify dendritic territories remain largely un
Autor:
Hiroyuki, Koizumi, Hiromi, Fujioka, Kazuya, Togashi, James, Thompson, John R, Yates, Joseph G, Gleeson, Kazuo, Emoto
Publikováno v:
Developmental neurobiology. 77(4)
Doublecortin-like kinase 1 (DCLK1) is a member of the neuronal microtubule-associated doublecortin (DCX) family and functions in multiple stages of neural development including radial migration and axon growth of cortical neurons. DCLK1 is suggested
Publikováno v:
Dendrites ISBN: 9784431560487
Dendrites are the entry site of neural signals into neurons. Once formed, dendrites do not maintain their structure, rather are dynamically remodeled in vivo: some dendrites are pruned away, while others lengthen and branch out. Dendritic remodeling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d7a7f9a5b38750931d2d72cd45a8c98
https://doi.org/10.1007/978-4-431-56050-0_12
https://doi.org/10.1007/978-4-431-56050-0_12