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Akademický článek

Fungal melanin suppresses airway epithelial chemokine secretion through blockade of calcium fluxing

Autor: Jennifer L. Reedy, Kirstine Nolling Jensen, Arianne J. Crossen, Kyle J. Basham, Rebecca A. Ward, Christopher M. Reardon, Hannah Brown Harding, Olivia W. Hepworth, Patricia Simaku, Geneva N. Kwaku, Kazuya Tone, Janet A. Willment, Delyth M. Reid, Mark H. T. Stappers, Gordon D. Brown, Jayaraj Rajagopal, Jatin M. Vyas

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Abstract Respiratory infections caused by the human fungal pathogen Aspergillus fumigatus are a major cause of mortality for immunocompromised patients. Exposure to these pathogens occurs through inhalation, although the role of the respiratory epith

Externí odkaz: https://doaj.org/article/e6887f3ec8884f338db33021a03541eb

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Akademický článek

Iliopsoas gravity abscess secondary to a tuberculous empyema

Autor: Kazuya Tone, Yuta Hirano, Kazuyoshi Kuwano

Publikováno v: International Journal of Mycobacteriology, Vol 10, Iss 3, Pp 335-337 (2021)

A 29-year-old Japanese man with a history of right-sided tuberculous pleurisy presented with fever and right flank pain. Computed tomography images revealed a right pleural effusion and an area of low attenuation in the right iliopsoas muscle. Percut

Externí odkaz: https://doaj.org/article/7bbc26282a2643f28d09ad23bfabc4c3

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Akademický článek

MelLec Exacerbates the Pathogenesis of Aspergillus fumigatus-Induced Allergic Inflammation in Mice

Autor: Kazuya Tone, Mark H. T. Stappers, Remi Hatinguais, Ivy M. Dambuza, Fabián Salazar, Carol Wallace, Raif Yuecel, Petruta L. Morvay, Kazuyoshi Kuwano, Janet A. Willment, Gordon D. Brown

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

Environmental factors, particularly fungi, influence the pathogenesis of allergic airway inflammation, but the mechanisms underlying these effects are still unclear. Melanin is one fungal component which is thought to modulate pulmonary inflammation.

Externí odkaz: https://doaj.org/article/2dc87d39964f46f59290f2b8ae8998df

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Mucus plugs and bronchial wall thickening on three-dimensional computed tomography in patients with unexplained chronic cough whose sputum yielded filamentous Basidiomycetes

Autor: Wataru Koda, Kenichiro Okumura, Takahiro Nadamura, Satoshi Kobayashi, Toshifumi Gabata, Haruhiko Ogawa, Teturo Igarashi, Yuichi Yoshie, Kazuya Tone, Kazuto Kozaka

Publikováno v: European Radiology. 30:3268-3276

This study was conducted in order to identify imaging features on three-dimensional computed tomography (CT) of unexplained chronic cough (UCC) patients with positive sputum cultures for filamentous Basidiomycetes (f-BM). UCC outpatients who had been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fbc30b4ff73463afff47689e9e1b583
https://doi.org/10.1007/s00330-020-06664-5

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